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T4962Zingibroside R1Human immunodeficiency virus,Zingibroside R 1,Zingibroside R-1,Zingibroside R1,Inhibi
Zingibroside R1 has anti-HIV-1 activity.
价 格:¥电议型 号:T4962产 地:中国大陆
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TN1525Convallatoxinpsoriasis,Nuclear factor-κB,P-gp,Inhibitor,anti-proliferative,colitic,anti-inflammatory
Convallatoxin is a natural product.
价 格:¥电议型 号:TN1525产 地:中国大陆
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T10696CB2 modulator 1CB2 modulator 1,ischemia,CB-2 modulator 1,osteoporosis,CB2,inflammation,immunedisorde
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
价 格:¥电议型 号:T10696产 地:中国大陆
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T9263cim0216cim-0216,cim0216,inflammation,inhibit,TRP Channel,Transient receptor potential channels,senso
CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.
价 格:¥电议型 号:T9263产 地:中国大陆
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T9570Enpatoraninhibit,M5049,Inhibitor,Toll-like Receptor (TLR),M-5049,autoimmunity,M 5049,TLR7/8,selectiv
Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM). Enpatoran was found to be inactive against TLR3, TLR4, and TLR9 in vitro and in vivo.
价 格:¥电议型 号:T9570产 地:中国大陆
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TWA2417Sodium taurocholateI nterleukin-1β,Tumor necrosis factor-α,inhibit,Sodium taurocholate hydrate,Immun
Taurocholic acid is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and deoxycholic acid.[3] These are reabsorbed by the liver via a carrier-mediated process and converted by liver enzymes to taurocholic acid.
价 格:¥电议型 号:TWA2417产 地:中国大陆
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T6S1027TussilagoneTussilagone,anti-inflammatory,puncture,dextran,murine,ligation,colitis,cecal,inhibit,sulp
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human colon cancer. 3. Tussilagone has anti-oxidant and anti-inflammatory activities, may be an effective oxygenase-1 inducer and a valuable compound for modulating inflammatory conditions. 4. Tussilagone has potential treatment of neuro-inflammatory diseases through the inhibition of ov
价 格:¥电议型 号:T6S1027产 地:中国大陆
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T7166GNE-493GNE493,Mammalian target of Rapamycin,PI3K,Inhibitor,inhibit,GNE-493,Phosphoinositide 3-kinase
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR,respectively.
价 格:¥电议型 号:T7166产 地:中国大陆
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T8768MM-102 TFAMM102,HMTase Inhibitor IX,MM-102,MM 102 TFA,MM 102,inhibit,MM102 TFA,Histone Methyltransfe
MM-102 TFA is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM. MM-102 compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5) and results in the inhibition of MLL1 H3K4 histone methyltransferase (HMT) activity. Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embry
价 格:¥电议型 号:T8768产 地:中国大陆
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TN2244Sulfuretininflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregati
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.
价 格:¥电议型 号:TN2244产 地:中国大陆
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T9926Omalizumabhumanized,asthma,IgE,CD40,allergic,IL-4,IL-6,FcγRIIb,Olizumab,Inhibitor,immunoglobulin,Fcε
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)
价 格:¥电议型 号:T9926产 地:中国大陆
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T6731WYE-354inhibit,Apoptosis,WYE354,WYE-354,WYE 354,Inhibitor,Autophagy,Mammalian target of Rapamycin,mT
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格:¥电议型 号:T6731产 地:中国大陆
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T7210Guanosine 5’-diphosphateanemia,inhibit,hepcidin,inflammation,Guanosine 5’-diphosphate,Potassium Chan
Guanosine 5´-diphosphate as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.
价 格:¥电议型 号:T7210产 地:中国大陆
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T6S0444Salvianolic acid AMatrix metalloproteinases,Salvianolic acid A,inhibit,MMP,Inhibitor
Salvianolic acid A could protect the blood brain barrier through inhibition of matrix metallopeptidase 9 (MMP-9) and anti-inflammation.
价 格:¥电议型 号:T6S0444产 地:中国大陆
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T7503UpadacitinibUpadacitinib,ABT 494,inhibit,Inhibitor,autoimmune,orally active,JAK,JAK1,ABT494,Janus ki
Upadacitinib (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM.
价 格:¥电议型 号:T7503产 地:中国大陆
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T6474Divalproex SodiumMitophagy,Notch,Apoptosis,Histone deacetylases,Autophagy,hepatic fat accumulation,H
Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC inhibitor. Divalproex Sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex may also work by suppressing r
价 格:¥电议型 号:T6474产 地:中国大陆
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T6S0117Avicularininhibit,inflammation,COX,Peroxisome proliferator-activated receptors,GLUT,oxidative stress
1. Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. 2. Avicularin inhibits the accumulation of the intracellular lipids by decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase.
价 格:¥电议型 号:T6S0117产 地:中国大陆
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TQ0297CenicrivirocCC chemokine receptor,inhibit,HIV,TBR 652,TAK 652,TBR652,Inhibitor,Human immunodeficienc
Cenicriviroc is an orally active, dual antagonist of CCR2/CCR5. It also inhibits both HIV-1 and HIV-2, and displays potent anti-infective and anti-inflammatory activity.
价 格:¥电议型 号:TQ0297产 地:中国大陆
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T7595L-DABAGamma-aminobutyric acid Receptor,Inhibitor,inhibit,LDABA,GABA Receptor,L DABA,Endogenous Metab
L-DAB HBR is an inhibitor of GABA transaminase (IC50 > 500 μM).
价 格:¥电议型 号:T7595产 地:中国大陆
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T9862Pseudocoptisine chlorideIsocoptisine,anti-amnestic,Pseudocoptisine chloride,cytokines,anti-inflammat
Pseudocoptisine chloride is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μM).
价 格:¥电议型 号:T9862产 地:中国大陆