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产品数:86101
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T7860SM-324405Inhibitor,Toll-like Receptor (TLR),low toxicity,TLR7,SM-324405,cytokine,diseases,immunother
SM 324405 is an agonist of TLR7.
价 格:¥电议型 号:T7860产 地:中国大陆
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T7136AZD-6280γ-Aminobutyric acid Receptor,GABA Receptor,inhibit,Gamma-aminobutyric acid Receptor,AZD6280,
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
价 格:¥电议型 号:T7136产 地:中国大陆
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T6574LumiracoxibCyclooxygenase,Inhibitor,bone cancer,osteoarthritis,inflammatory,COX189,inhibit,hyperalge
Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
价 格:¥电议型 号:T6574产 地:中国大陆
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T6420BMS-707035BMS 707035,HIV-1 integrase strand transfer,HIV,Human immunodeficiency virus,antiviral,BMS7
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:中国大陆
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TL0007Bisdemethoxycurcumininhibit,Inhibitor,Bisdemethoxycurcumin,antiinflammatory,curcuminoid,antioxidant,
Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expres
价 格:¥电议型 号:TL0007产 地:中国大陆
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T6418BMS-378806BMS 378806,BMS 806,Human immunodeficiency virus,inhibit,HIV,BMS-378806,BMS806,Inhibitor
BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
价 格:¥电议型 号:T6418产 地:中国大陆
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T8313HCH6-1inhibit,inflammatory,FPR1,HCH6-1,cell infiltration,HCH6 1,antagonist,pulmonary,acute lung inju
HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist.
价 格:¥电议型 号:T8313产 地:中国大陆
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T9080PlecanatideInhibitor,Guanylate Cyclase,chronic,inhibit,anti-inflammatory,Plecanatide,idiopathic,GC-C
Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.
价 格:¥电议型 号:T9080产 地:中国大陆
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T6403Siponimodinflammation,BAF312,Lysophospholipid Receptor,S1P receptor,inhibit,neurodegeneration,S1P1 a
BAF312 (Siponimod), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibits >1000-fold over S1P2, S1P3 and S1P4 receptors.
价 格:¥电议型 号:T6403产 地:中国大陆
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T6246CobicistatInhibitor,HIV,Human immunodeficiency virus,antiviral,HIV-1,Cytochrome P450,CYPs,CYP3A,Cobi
Cobicistat is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS.
价 格:¥电议型 号:T6246产 地:中国大陆
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T9831MKC-1inhibit,mTOR,Apoptosis,Protein kinase B,PKB,MKC 1,renal cell cancer,Caki-1,Mammalian target of
MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in
价 格:¥电议型 号:T9831产 地:中国大陆
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T8705BOT-64IL-6,BOT64,I kappa B kinase,inhibit,inflammatory,BOT-64,NF-κb,RAW 264.7,IKK,IκB kinase,Inhibit
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase´s activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound
价 格:¥电议型 号:T8705产 地:中国大陆
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T8564BC-1382interaction,Anti-inflammatory,ligase,Inhibitor,lung,Ubiquitin,E1 activating enzyme,Ubiquitin
BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5 nM).
价 格:¥电议型 号:T8564产 地:中国大陆
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T6559Rhamnose monohydrateRhamnose monohydrate,Rhamnose,Inhibitor,immunotherapies,cancer,monosaccharide,in
L(+)-Rhamnose (Rham) is a naturally-occurring deoxy sugar that is found primarily in plants and some bacteria.
价 格:¥电议型 号:T6559产 地:中国大陆
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TN2290Uvaolantioxidant,allergy,Pleuritis,Inhibitor,Endogenous Metabolite,inflammation,inhibit,eosinophilic
Uvaol is present in olives and virgin olive oil with anti-inflammatory, anti-proliferative, and vasorelaxant activities.
价 格:¥电议型 号:TN2290产 地:中国大陆
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TN4893Rapanoneantioxidant,anti-inflammatory,Bacterial,inhibit,anti-tumor,Phospholipase,antiparasiti,synovi
Rapanone is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.
价 格:¥电议型 号:TN4893产 地:中国大陆
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T7282Tenofovir alafenamide hemifumarateInhibitor,Human immunodeficiency virus,inhibit,Tenofovir alafenami
Tenofovir alafenamide fumarate (TAF) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV)
价 格:¥电议型 号:T7282产 地:中国大陆
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T9039HIV-1 Nef-IN-1antiviral,HIV 1 Nef IN 1,SH3,HIV1 NefIN1,HIV,PPI,Nef,Inhibitor,inhibit,HIV-1,Human imm
HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).
价 格:¥电议型 号:T9039产 地:中国大陆
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TN6700gamma-Nonanolactonegamma Nonanolactone,gammaNonanolactone
gamma-Nonanolactone is an aroma component of steamed wheat.
价 格:¥电议型 号:TN6700产 地:中国大陆
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TP1809TATPeptide,Inhibitor,HIV-1,HIV,TAT,inhibit,Human immunodeficiency virus
TAT (YGRKKRRQRRR) is a cell-penetrating peptide derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1). TAT can increase the yields and the solubility of heterologous proteins[1].
价 格:¥电议型 号:TP1809产 地:中国大陆