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产品数:86101
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TN6735Bigelovininhibit,Autophagy,Inhibitor,Retinoic acid receptors,Bigelovin,Retinoid X receptors,Apoptosi
Bigelovin is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.It is also known as a potent cytotoxic sesquiterpene lactone from Inula sp.
价 格:¥电议型 号:TN6735产 地:中国大陆
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T6837FlavopiridolHMR1275,inhibit,L86-8275,CDK,Cyclin dependent kinase,Inhibitor,Autophagy,HMR 1275,Human
Flavopiridol (Alvocidib) competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1, 2, 4, 6 versus CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. Phase 1/2.
价 格:¥电议型 号:T6837产 地:中国大陆
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T6396(R)-(-)-Gossypol acetic acidBcl-2 Family,Autophagy,(R) ( ) Gossypol acetic acid,Inhibitor,(R)()Gossy
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2.
价 格:¥电议型 号:T6396产 地:中国大陆
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T8991BMS986187leu-enkephalin,inhibit,PAM,BMS 986187,δ-opioid,Opioid Receptor,CHO-OPRD1 cell,BMS986187,BMS
BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.
价 格:¥电议型 号:T8991产 地:中国大陆
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T12753RORγt Inverse agonist 6Inhibitor,ROR,RORγt Inverse agonist-6,inhibit,RAR-related orphan receptor,ROR
RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.
价 格:¥电议型 号:T12753产 地:中国大陆
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T8200Ginkgolide KGinkgolide K,Autophagy,inhibit,Inhibitor
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.
价 格:¥电议型 号:T8200产 地:中国大陆
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T7820Raphin1Raphin1,Raphin 1,Raphin-1,Phosphatase,inhibit,Inhibitor
Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B).
价 格:¥电议型 号:T7820产 地:中国大陆
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T7322TheliatinibATP-competitive,inhibit,EGFR,ERK,cancer,esophageal,Epidermal growth factor receptor,HMPL-
Theliatinib, a potent and highly selective EGFR inhibitor, with anti-tumor activity. Ki of 0.05 nM for wild type EGFR, and IC50s of 3 and 22 nM for EGFR and EGFR T790M/L858R mutant, respectively.
价 格:¥电议型 号:T7322产 地:中国大陆
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TQ0007Cintirorgoninhibit,LYC 55716,ROR,RAR-related orphan receptor,LYC55716,Inhibitor,Cintirorgon
Cintirorgon is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells.
价 格:¥电议型 号:TQ0007产 地:中国大陆
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T6S2116Ginkgolic acid C17:1Phosphatase and tensin homolog,PTEN,Phosphatase,Inhibitor,MMAC1,inhibit,Ginkgoli
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.
价 格:¥电议型 号:T6S2116产 地:中国大陆
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T9156CDC25B-IN-2Inhibitor,CDC-25B-IN-2,CDC25BIN2,Phosphatase,CDC25B IN 2,inhibit
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
价 格:¥电议型 号:T9156产 地:中国大陆
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T6911NSC-87877 disodiumApoptosis,Neuroblastoma,inhibit,Inhibitor,NSC 87877 disodium,PPAR,p53,Phosphatase,
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格:¥电议型 号:T6911产 地:中国大陆
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T8281(R)-Sulforaphaneinhibit,(R)-Sulforaphane,(R) Sulforaphane,(R)Sulforaphane,Inhibitor
(R)-Sulforaphane is a potent inducer of the Keap1/Nrf2/ARE pathway.
价 格:¥电议型 号:T8281产 地:中国大陆
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TN12573-O-Acetyl-α-boswellic acidinhibit,α-Boswellic acid,3 O Acetyl α boswellic acid,Inhibitor,3OAcetylαb
3-O-Acetyl-α-boswellic acid has strong anti-inflammatory activity.
价 格:¥电议型 号:TN1257产 地:中国大陆
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T8483Cysteine thiol probepharmacophore,inhibit,Cysteine thiol probe,products,enone-based,chromophore,thio
Cysteine thiol probe is a chemoselective thiol probe for detection of electrophilic metabolites
价 格:¥电议型 号:T8483产 地:中国大陆
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T9205NCGC00378430NCGC-00378430,Inhibitor,T47D,E-CAD,MCF7,Phosphatase,NCGC 00378430,TGF-β,inhibit,NCGC0037
NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor that disrupts the SIX1/EYA2 complex, EMT, and Metastasis.
价 格:¥电议型 号:T9205产 地:中国大陆
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T6S1699ShogaolInhibitor,Shogaol,Autophagy,inhibit
1. 6-Shogaol has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol e
价 格:¥电议型 号:T6S1699产 地:中国大陆
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T8732CTPI-2macrophage,carrier,CTPI-2,NSCLC,transporter,glucose,steatohepatitis,CTPI 2,Mitochondrial Metab
CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet.
价 格:¥电议型 号:T8732产 地:中国大陆
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T6580MeprednisoneMeprednisone,Autophagy,Glucocorticoid Receptor,Inhibitor,inhibit
Betapar(Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
价 格:¥电议型 号:T6580产 地:中国大陆
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TP1367[D-Ala2]leucine-enkephalinOpioid Receptor,[DAla2]leucineenkephalin,Inhibitor,[D Ala2]leucine enkepha
[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.
价 格:¥电议型 号:TP1367产 地:中国大陆