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T78274Omburtamab;奥博妥单抗Omburtamab
Omburtamab is a monoclonal antibody targeting CD276, often conjugated to 131 radioactive iodine ions, used for radioimmuno positron emission tomography studies.
价 格:¥电议型 号:T78274产 地:中国大陆
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T78253Faricimab;化合物 FaricimabRG7716;RG7716
Faricimab, a bispecific antibody, simultaneously targets angiopoietin-2 and vascular endothelial growth factor-A (VEGF-A), and is utilized in research on diabetic macular edema (DME) [1].
价 格:¥电议型 号:T78253产 地:中国大陆
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T78252Bebtelovimab;化合物 BebtelovimabLY-3853113|||LY-COV1404;LY-3853113|||LY-COV1404
Bebtelovimab is a humanized IgG1-λ2 antibody specifically targeting SARS-CoV-2 and has demonstrated potent neutralization against its variants, exhibiting mild-to-moderate efficacy in inhibiting COVID-19 [1] [2].
价 格:¥电议型 号:T78252产 地:中国大陆
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T78251Sotigalimab;化合物 SotigalimabSotigalimab
Sotigalimab, a CD40 agonistic monoclonal antibody, is utilized in research targeting metastatic pancreatic adenocarcinoma [1].
价 格:¥电议型 号:T78251产 地:中国大陆
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T78250Selicrelumab;化合物 SelicrelumabSelicrelumab
Selicrelumab, an agonist CD40 antibody, modifies the tumor microenvironment and is utilized in pancreatic cancer research and neoadjuvant studies [1].
价 格:¥电议型 号:T78250产 地:中国大陆
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T78249Nipocalimab;化合物 NipocalimabM281;M281
Nipocalimab (M281), a fully human, recombinant, aglycosylated IgG1 monoclonal antibody, exhibits high-affinity binding to the Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6, characterized by its picomolar affinity and specificity as a human deglycosylated anti-FcRn monoclonal antibody [1] [2].
价 格:¥电议型 号:T78249产 地:中国大陆
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T78248Nesvacumab;化合物 NesvacumabNesvacumab
Nesvacumab, a fully human immunoglobulin G1 (IgG1) monoclonal antibody, selectively binds to and inactivates Angiopoietin-2 (Ang2), the ligand for the Tie2 receptor, with high affinity, while exhibiting no affinity for Angiopoietin-1 (Ang1) [1].
价 格:¥电议型 号:T78248产 地:中国大陆
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T78247Ieramilimab;埃拉利单抗IMP701|||LAG525;IMP701|||LAG525
Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that targets LAG-3, disrupting its interaction with MHC-II molecules [1].
价 格:¥电议型 号:T78247产 地:中国大陆
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T78246Lemzoparlimab;来佐利单抗TJC4|||TJ011133;TJC4|||TJ011133
Lemzoparlimab (TJ011133; TJC4), a humanized anti-CD47 IgG4 antibody, exhibits potent antitumor activity [1].
价 格:¥电议型 号:T78246产 地:中国大陆
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T78245Batoclimab;化合物 BatoclimabIMVT-1401|||HBM9161;IMVT-1401|||HBM9161
Batoclimab, a human anti-FcRn monoclonal antibody, is utilized in the study of IgG-mediated autoimmune diseases [1].
价 格:¥电议型 号:T78245产 地:中国大陆
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T78065Enfortumab vedotin-ejfv;化合物 Enfortumab vedotin-ejfvEnfortumab vedotin-ejfv
Enfortumab vedotin-ejfv is an antibody-drug conjugate targeting Nectin-4, employed in the treatment of urothelial carcinoma [1].
价 格:¥电议型 号:T78065产 地:中国大陆
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T78047Gemtuzumab ozogamicin;化合物 Gemtuzumab ozogamicinGemtuzumab ozogamicin
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) that comprises a monoclonal antibody specific to CD33 conjugated to a cytotoxic agent derived from Calicheamicin. It is utilized in the investigation of acute myeloid leukemia [1].
价 格:¥电议型 号:T78047产 地:中国大陆
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T77911Cantuzumab;化合物 CantuzumabCantuzumab
Cantuzumab, a monoclonal antibody, binds to the CanAg antigen and is commonly conjugated with various cytotoxic agents to form antibody-drug conjugates (ADCs), including Cantuzumab mertansine and Cantuzumab ravtansine [1].
价 格:¥电议型 号:T77911产 地:中国大陆
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T77910Patritumab deruxtecan;化合物 Patritumab deruxtecanU3-1287|||HER3-DXd;U3-1287|||HER3-DXd
Patritumab deruxtecan (HER3-DXd), an antibody-drug conjugate (ADC), comprises a fully human anti-HER3 IgG1 monoclonal antibody, Patritumab, linked to a topoisomerase I inhibitor payload through a tetrapeptide-based cleavable linker, demonstrating anticancer activity [1].
价 格:¥电议型 号:T77910产 地:中国大陆
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T77909Mirzotamab;化合物 MirzotamabMirzotamab
Mirzotamab is an IgG1κ antibody targeting CD276/B7-H3 and is the naked antibody to Mirzotamab clezutoclax, consisting of 1320 amino acids.
价 格:¥电议型 号:T77909产 地:中国大陆
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T77908Farletuzumab ecteribulin;化合物 Farletuzumab ecteribulinMORAb-202;MORAb-202
Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-eribulin through reduced interchain disulfide bonds, with an agent-to-antibody ratio of 4.0. It demonstrates potent antitumor activity against FRA-positive cells in vitro.
价 格:¥电议型 号:T77908产 地:中国大陆
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T77907Tusamitamab ravtansine;化合物 Tusamitamab ravtansineHuMAb2-3-SPDB-DM4|||SAR-408701;HuMAb2-3-SPDB-DM4|||
Tusamitamab ravtansine (SAR-408701) is a DM4-linked anti-CEACAM5 antibody-drug conjugate (ADC) comprising a humanized monoclonal antibody targeting carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) conjugated to a cytotoxic maytansinoid, selectively engaging CEACAM5-positive tumor cells [1].
价 格:¥电议型 号:T77907产 地:中国大陆
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T77905Vobramitamab;化合物 VobramitamabAEX-4089;AEX-4089
Vobramitamab, a humanized B7-H3 monoclonal antibody (mAb), is conjugated to the prodrug seco-DUBA through a cleavable linker, creating the antibody-drug conjugate (ADC) known as MGC018 [1].
价 格:¥电议型 号:T77905产 地:中国大陆
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T77903Belantamab mafodotin;化合物 Belantamab mafodotinBelantamab mafodotin-blm|||GSK2857916;Belantamab mafodo
Belantamab mafodotin (GSK2857916) is a conjugate of a humanized, targeted monoclonal antibody directed against the B cell maturation antigen (BCMA) and the cytotoxic agent McMMAF, exhibiting anti-myeloma activity [1] [2].
价 格:¥电议型 号:T77903产 地:中国大陆
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T77881Tisotumab vedotin;化合物 Tisotumab vedotinTisotumab vedotin
Tisotumab vedotin is an antibody-drug conjugate (ADC) that specifically targets tissue factor (TF). This compound combines a fully human monoclonal antibody directed against TF (TF-011) with the cytotoxic agent Monomethyl Auristatin E (MMAE), exhibiting potent antitumor activity in the investigation of advanced or metastatic solid tumors [1].
价 格:¥电议型 号:T77881产 地:中国大陆