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T78323Letaplimab;化合物 LetaplimabIBI-188;IBI-188
Letaplimab (IBI-188), a humanized IgG4 monoclonal antibody targeting CD47—which is often overexpressed in cancer cells and acts as a ligand for SIRPα—has been shown to promote phagocytosis of tumor cells [1].
价 格:¥电议型 号:T78323产 地:中国大陆
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T78322Lesabelimab;化合物 LesabelimabLDP;LDP
Lesabelimab (LDP) is an anti-CD274 monoclonal antibody of the immunoglobulin G1-kappa subclass. It targets CD274, an immune checkpoint ligand that suppresses antitumor immunity by engaging with the PDCD1 receptor [1] [2].
价 格:¥电议型 号:T78322产 地:中国大陆
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T78321Izenivetmab;化合物 IzenivetmabZTS-00075623;ZTS-00075623
Izenivetmab (ZTS-00075623) is a caninized IgG2κ monoclonal antibody targeting NGFB [1].
价 格:¥电议型 号:T78321产 地:中国大陆
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T78320Ginisortamab;化合物 GinisortamabUCB6114;UCB6114
Ginisortamab (UCB6114), a fully human IgG4P monoclonal antibody targeting Gremlin-1, shows potential for investigating gastrointestinal (GI) tumors [1].
价 格:¥电议型 号:T78320产 地:中国大陆
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T78319Gatralimab;化合物 GatralimabGZ-402668;GZ-402668
Gatralimab (GZ-402668) is an IgG1 monoclonal antibody targeting CD52.
价 格:¥电议型 号:T78319产 地:中国大陆
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T78318Gatipotuzumab;化合物 GatipotuzumabPankoMab;PankoMab
Gatipotuzumab (PankoMab), a humanized monoclonal antibody, targets the tumor-specific epitope TA-MUC1 of mucin-1 and exhibits potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) [1] [2].
价 格:¥电议型 号:T78318产 地:中国大陆
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T78317Blinatumomab;化合物 BlinatumomabAnatumomab;Anatumomab
Blinatumomab (formerly known as Anatumomab) is a bispecific monoclonal antibody that specifically targets the CD19 antigen on B cells and is utilized in the study of acute lymphoblastic leukemia [1].
价 格:¥电议型 号:T78317产 地:中国大陆
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T78316Frunevetmab;夫卢维单抗NV-02;NV-02
Frunevetmab (NV-02), a felinized monoclonal antibody targeting nerve growth factor (NGF), exhibits a high affinity with a dissociation constant (Kd) of 20 pM and has been demonstrated to effectively mitigate osteoarthritis (OA) pain in cats [1] [2].
价 格:¥电议型 号:T78316产 地:中国大陆
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T78315Foravirumab;福拉韦单抗CR4098;CR4098
Foravirumab (CR4098) is a monoclonal antibody targeting antigenic site III of the rabies virus glycoprotein [1].
价 格:¥电议型 号:T78315产 地:中国大陆
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T78314Fianlimab;化合物 FianlimabREGN3767;REGN3767
Fianlimab (REGN3767) is a human monoclonal antibody targeting the LAG-3 immune checkpoint receptor on T cells, exhibiting anti-tumor activity [1].
价 格:¥电议型 号:T78314产 地:中国大陆
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T78313Fazpilodemab;化合物 FazpilodemabBFKB8488A;BFKB8488A
Fazpilodemab (BFKB8488A) is a humanized agonistic bispecific antibody that targets fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. It is utilized in research pertaining to Type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD) [1].
价 格:¥电议型 号:T78313产 地:中国大陆
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T78312Cifurtilimab;化合物 CifurtilimabSEA-CD40;SEA-CD40
Cifurtilimab (SEA-CD40), a nonfucosylated humanized IgG1 monoclonal antibody with agonistic properties, targets the CD40 receptor and demonstrates antitumor activities [1] [2].
价 格:¥电议型 号:T78312产 地:中国大陆
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T78311Sontuzumab;松妥组单抗huHMFG-1|||AS1402;huHMFG-1|||AS1402
Sontuzumab (AS1402), a humanized IgG1κ monoclonal antibody targeting MUC1, exhibits high affinity, with a dissociation constant (Kd) of approximately 1 nM for the extracellular peptide sequence PDTR of MUC1. It is utilized in breast cancer research [1].
价 格:¥电议型 号:T78311产 地:中国大陆
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T78310Raxibacumab;化合物 RaxibacumabABthrax;ABthrax
Raxibacumab (ABthrax), a human IgG1 monoclonal antibody, targets the protective antigen (PA) of Bacillus anthracis. It inhibits the toxic impact of anthrax by obstructing the PA´s attachment to host cell receptors, preventing the subsequent harmful effects. This compound is utilized in anti-anthrax research [1] [2].
价 格:¥电议型 号:T78310产 地:中国大陆
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T78308Tenatumomab;化合物 TenatumomabST2146;ST2146
Tenatumomab (ST2146), a murine monoclonal antibody targeting tenascin-C—a largely overexpressed extracellular glycoprotein in cancer—facilitates Pretargeted Antibody Guided Radioimmunotherapy (PAGRIT) by delivering radionuclides to tumors using both PAGRIT and direct ^131Iodine labeling approaches [1] [2].
价 格:¥电议型 号:T78308产 地:中国大陆
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T78307Catumaxomab;化合物 CatumaxomabCatumaxomab
Catumaxomab, a trifunctional IgG2 antibody with mouse and rat heavy and light chain components, targets human EpCAM and CD3 receptors. Its Fc region exhibits affinity for FcγRI (CD64), FcγRIIA (CD32a), and FcγRIII (CD16), making it a valuable tool in epithelial cancer anti-tumor research [1] [2].
价 格:¥电议型 号:T78307产 地:中国大陆
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T78306Ulenistamab;尤尼妥单抗PBP1510;PBP1510
Ulenistamab (PBP1510) is a first-in-class humanized IgG1 monoclonal antibody that targets the pancreatic adenocarcinoma upregulated factor (PAUF), and is utilized in pancreatic cancer (PC) research [1].
价 格:¥电议型 号:T78306产 地:中国大陆
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T78305Briquilimab;化合物 BriquilimabJSP-191;JSP-191
Briquilimab (JSP-191), a non-toxic humanized monoclonal antibody, targets CD117 (c-Kit) to deplete hematopoietic stem cells (HSCs), providing a safe approach for clearing host marrow niche to facilitate adequate donor HSC engraftment and immune reconstitution, primarily in the treatment of severe combined immunodeficiency (SCID) [1].
价 格:¥电议型 号:T78305产 地:中国大陆
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T78304Bapotulimab;巴泊妥利单抗BAY-1905254;BAY-1905254
Bapotulimab (BAY-1905254) is a fully human IgG2 antibody that targets the immunoglobulin-like domain-containing receptor 2 (ILDR2), exhibiting antitumor and immunosuppressive effects [1].
价 格:¥电议型 号:T78304产 地:中国大陆
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T78301Aselizumab;化合物 AselizumabHuDreg-55;HuDreg-55
Aselizumab (HuDreg-55) is a humanized IgG4 monoclonal antibody (mAb) targeting L-selectin (CD62L), a cell adhesion molecule found on circulating neutrophils that directs cell migration through chemotaxis to injury sites. Notably, Aselizumab has been associated with an increased incidence of infections and leukopenia following trauma [1] [2].
价 格:¥电议型 号:T78301产 地:中国大陆