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  • T6S1653Albiflorin;芍药内酯苷Alibiflorin;Alibiflorin|||芍药内酯苷

    1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced reduction of cell viability, nuclear and mitochondrial apoptotic alteration, reactive oxygen species accumulation and B-cell lymphoma 2 (Bcl-2)/Bax ratio. 4. Albiflorin can serve as a new chemical marker for the quality control of Paeoniae Radix and the Chinese Pharmacopoeia can

    价 格:¥电议型 号:T6S1653产 地:中国大陆

  • T6S1652Benzoylpaeoniflorin;苯甲酰芍药苷Benzoylpaeoniflorin

    1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.

    价 格:¥电议型 号:T6S1652产 地:中国大陆

  • T69165Methiothepin methanesulfonate;化合物 Methiothepin methanesulfonateMethiothepin methanesulfonate

    Methiothepin methanesulfonate is an inhibitor of HCV infection and cell-to-cell transmission that acts by targeting the HCV E2 glycoprotein.

    价 格:¥电议型 号:T69165产 地:中国大陆

  • T68470ASB-16165;化合物 ASB-16165ASB-16165

    ASB-16165 is a phosphodiesterase 7A inhibitor that impairs proliferation of keratinocytes in vitro and in vivo. Inhibitors of PDE7A including ASB16165 might be useful for the treatment of psoriasis.

    价 格:¥电议型 号:T68470产 地:中国大陆

  • T68306INCB16562;化合物 INCB16562INCB16562

    INCB16562 is a novel, selective, and orally bioavailable small-molecule inhibitor of JAK1 and JAK2 markedly selective over JAK3. Treatment of myeloma cells with INCB16562 potently inhibited interleukin-6 (IL-6)-induced phosphorylation of STAT3. INCB16562 abrogated the protective effects of recombinant cytokines or bone marrow stromal cells and sensitized myeloma cells to cell death by exposure to dexamethasone, melphalan, or bortezomib. Oral administration of INCB16562 antagonized the growth of

    价 格:¥电议型 号:T68306产 地:中国大陆

  • T68165Trapencaine;曲喷卡因Trapencaine

    Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.

    价 格:¥电议型 号:T68165产 地:中国大陆

  • T671652-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid;化合物 2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-y

    2-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T67165 and the CAS number is 4113-97-7.

    价 格:¥电议型 号:T67165产 地:中国大陆

  • T661653,4-Dimethoxy-2-methylpyridine 1-oxide;化合物 3,4-Dimethoxy-2-methylpyridine 1-oxide3,4-Dimethoxy-2-met

    3,4-Dimethoxy-2-methylpyridine 1-oxide is a useful organic compound for research related to life sciences and the catalog number is T66165.

    价 格:¥电议型 号:T66165产 地:中国大陆

  • T65165EDTA disodium manganese salt;化合物 EDTA disodium manganese saltEDTA disodium manganese salt

    EDTA disodium manganese salt is a useful organic compound for research related to life sciences. The catalog number is T65165 and the CAS number is 15375-84-5.

    价 格:¥电议型 号:T65165产 地:中国大陆

  • T64165Gln-AMS TFA;化合物 Gln-AMS TFAGln-AMS TFA

    Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.

    价 格:¥电议型 号:T64165产 地:中国大陆

  • T63955MU1656;化合物 MU1656MU1656

    MU1656, a potent and selective histone methyltransferase DOT1L inhibitor, demonstrates an IC50 of 2 nM. It is applicable in the research of hematological malignancies [1].

    价 格:¥电议型 号:T63955产 地:中国大陆

  • T63165LX-039;化合物 LX-039LX-039

    LX-039 is a potent, selective, orally active estrogen receptor degrader (EC50: 2.99 nM) with antitumor effects.LX-039 has indole C-3 chloride atoms.LX-039 has good pharmacokinetic properties in mice, low clearance, high blood levels and oral exposure.

    价 格:¥电议型 号:T63165产 地:中国大陆

  • T62165PI3Kγ inhibitor 4;化合物 PI3Kγ inhibitor 4PI3Kγ inhibitor 4

    PI3Kγ inhibitor 4 is a selective, potent, orally active PI3Kγ inhibitor (IC50: 40 nM). PI3Kγ inhibitor 4 is ~7-fold more selective for PI3Kγ than the α subtype, 43-fold more selective than the β subtype and 18-fold more selective than the δ subtype. inflammation.

    价 格:¥电议型 号:T62165产 地:中国大陆

  • T62097UNC10201652;化合物 UNC10201652UNC10201652

    UNC10201652 is a potent inhibitor of L1-specific intestinal bacterial β-glucuronidases (GUSs) and is able to act on Escherichia coli (E. coli) (IC50: 0.117 μM). glucuronide processing.

    价 格:¥电议型 号:T62097产 地:中国大陆

  • T61659CC214-2;化合物 CC214-2CC214-2

    CC214-2 is a potent dual inhibitor of mTORC1 and mTORC2, known for its ability to impede autophagy by modulating mammalian target of rapamycin (mTOR) signaling. With this capacity, CC214-2 shows promise in shortening the duration of tuberculosis (TB) [1].

    价 格:¥电议型 号:T61659产 地:中国大陆

  • T61658TYK2-IN-11;化合物 TYK2-IN-11TYK2-IN-11

    TYK2-IN-11 (Compound 5B) is a potent and selective inhibitor of Tyk-2, providing inhibition to TYK2-JH2 and JAK1-JH2 with IC50 values of 0.016 nM and 0.31 nM, respectively. This compound demonstrates potential for advancing research in the area of inflammatory and autoimmune diseases [1].

    价 格:¥电议型 号:T61658产 地:中国大陆

  • T61657Rucaparib acetate;化合物 Rucaparib acetateRucaparib acetate

    Rucaparib (AG014699) acetate is a highly effective oral inhibitor of PARP proteins, specifically targeting PARP-1, PARP-2, and PARP-3, with a Ki value of 1.4 nM for PARP1. Additionally, it exhibits inhibitory action on hexose-6-phosphate dehydrogenase (H6PD) to a moderate extent. Rucaparib acetate shows promise in the field of research for castration-resistant prostate cancer (CRPC). [1] [2] [3] [4]

    价 格:¥电议型 号:T61657产 地:中国大陆

  • T61656Antitumor agent-53;化合物 Antitumor agent-53Antitumor agent-53

    Antitumor agent-53 is a potent compound that effectively inhibits tumor growth. It achieves this by inducing cell cycle arrest at the G2/M phase and promoting apoptosis in HGC-27 cells through the inhibition of the PI3K/AKT pathway. Furthermore, Antitumor agent-53 holds promise for further research in the treatment of gastrointestinal tumors [1].

    价 格:¥电议型 号:T61656产 地:中国大陆

  • T61655AM-1488;化合物 AM-1488AM-1488

    AM1488 is a potent, orally active glycine receptor ( GlyR ) potentiator (hGlyRα3 EC 50 =0.45 μM) [1] [2].

    价 格:¥电议型 号:T61655产 地:中国大陆

  • T61654PI3Kα-IN-9;化合物 PI3Kα-IN-9PI3Kα-IN-9

    PI3Kα-IN-9 (compound 27) is a highly specific, orally active, and long-lasting inhibitor of PI3Kα, demonstrating potent inhibitory effects with IC50 values of 4.4, 128, 146, and 153 nM against PI3Kα, PI3Kγ, PI3Kδ, and PI3Kβ, respectively. Additionally, PI3Kα-IN-9 exhibits antiproliferative properties and effectively induces apoptosis. Given its characteristics, PI3Kα-IN-9 holds great potential for cancer research [1].

    价 格:¥电议型 号:T61654产 地:中国大陆

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