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T61653VPC-13789;化合物 VPC-13789VPC-13789
VPC-13789 is a highly potent, selective, and orally bioavailable antiandrogen compound that shows promise for studying and developing therapeutics for castration-resistant prostate cancer (CRPC). In LNCaP cells, VPC-13789 effectively inhibits the transcriptional activity of the androgen receptor (AR) with an IC50 value of 0.19 μM [1].
价 格:¥电议型 号:T61653产 地:中国大陆
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T61652WIN 54954;化合物 WIN 54954WIN 54954
WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections.
价 格:¥电议型 号:T61652产 地:中国大陆
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T61651Quinoprazine;化合物 QuinoprazineQuinoprazine
Quinoprazine, a powerful inhibitor of Vaccinia virus DNA synthesis (IC50 = 10 μM), exhibits notable antimalarial activity against Plasmodium berghei. Additionally, it demonstrates significant antiprion potency, effectively reducing levels of PrPSc [1]-[5].
价 格:¥电议型 号:T61651产 地:中国大陆
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T61650CXCR4 antagonist 9;化合物 CXCR4 antagonist 9CXCR4 antagonist 9
CXCR4 antagonist 9 (Compound 2) is a potent CXCR4 antagonist displaying an IC50 of 15 nM. It effectively inhibits the cytosolic calcium increase induced by CXCL12, with an IC50 value of 1.3 nM [1].
价 格:¥电议型 号:T61650产 地:中国大陆
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T6165Bardoxolone Methyl;甲基巴多索隆RTA 402|||CDDO Methyl ester|||TP-155|||NSC 713200;RTA 402|||CDDO Methyl est
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities.
价 格:¥电议型 号:T6165产 地:中国大陆
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T6124Mubritinib;木利替尼TAK-165;木利替尼|||TAK-165
Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.
价 格:¥电议型 号:T6124产 地:中国大陆
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T6060LAnabasine HCl;化合物 T6060LBB-NC-0036|||CCG-38440|||H-8174|||AR-1H7273|||ZX-BK000320|||ST-24041653;BB-N
Anabasine HCl is used as a clinical biomarker for tobacco smoke exposure and as an insecticide. It is also a depolarizing NMJ blocker, aromatase inhibitor, nAChr antagonist, and teratogen found in species of Nicotiana.
价 格:¥电议型 号:T6060L产 地:中国大陆
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T60165VB124;化合物VB124VB124
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for lactate import and export, respectively, in MDA-MB-231 cells. Its high selectivity for MCT4 over MCT1 positions VB124 as a promising agent for researching cardiac hypertrophy, heart failure, and metabolic disorders [1].
价 格:¥电议型 号:T60165产 地:中国大陆
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T5S1058Triptonide;雷公藤内酯酮PG 492|||NSC 165677;雷公藤内酯酮|||PG 492|||NSC 165677
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.
价 格:¥电议型 号:T5S1058产 地:中国大陆
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T516510-Deacetyltaxol;10-去乙酰紫杉醇10-DAT|||10-Desacetyl Paclitaxel|||Deacetyltaxol|||10-deacetyl-paclitaxel|
10-Deacetyltaxol (10-DAT) is extracted from Taxus brevifolia barks.
价 格:¥电议型 号:T5165产 地:中国大陆
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T4S1659Xanthotoxol;花椒毒酚8-Hydroxypsoralen|||8-Hydroxyfuranocoumarin|||Psoralen|||8-Hydroxypsoralene;8-Hydrox
Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
价 格:¥电议型 号:T4S1659产 地:中国大陆
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T4S1658Benzoyloxypaeoniflorin;苯甲酰氧化芍药苷Benzoyloxypeoniflorin;苯甲酰氧化芍药苷|||Benzoyloxypeoniflorin|||苯甲酰氧芍药苷
Benzoyloxypaeoniflorin (Benzoyloxypeoniflorin) is a natural product,contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.
价 格:¥电议型 号:T4S1658产 地:中国大陆
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T4688Pipequaline hydrochloride;盐酸哌夸林PK-8165 hydrochloride;PK-8165 hydrochloride|||盐酸哌夸林
Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.
价 格:¥电议型 号:T4688产 地:中国大陆
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T4655Pipequaline哌夸林PK-8165|||哌夸林
Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.
价 格:¥电议型 号:T4655产 地:中国大陆
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T4165Delpazolid;化合物DelpazolidLCB01-0371;LCB01-0371
Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacter
价 格:¥电议型 号:T4165产 地:中国大陆
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T41165ETP 45835 dihydrochloride;ETP 45835 dihydrochlorideETP 45835 dihydrochloride
ETP 45835 dihydrochloride is a Mnk2 and Mnk1 inhibitor (IC50 values are 575 and 646 nM respectively). Exhibits selectivity against a panel of 24 protein Ki nases, including those upstream of Mnk1/2.
价 格:¥电议型 号:T41165产 地:中国大陆
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T40165OM99-2 TFA;OM99-2 TFAOM99-2 TFA;OM99-2 TFA
OM99-2 TFA is an eight-residue peptidomimetic compound, functioning as a tight-binding inhibitor of human brain memapsin 2. It exhibits a high affinity for the target with a Ki value of 9.58 nM, making it a promising candidate in the development of BACE1 inhibitors. Due to its potential, OM99-2 presents opportunities for further research in the field of Alzheimer´s disease.
价 格:¥电议型 号:T40165产 地:中国大陆
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T3S0165Atractylone;苍术酮Atractylon;Atractylon|||苍术酮
Atractylone (Atractylon) has the functions of protecting liver, lowering blood sugar, antibacterial, anti-tumor and anti-virus.
价 格:¥电议型 号:T3S0165产 地:中国大陆
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T38165FBBBE;FBBBEFBBBE
FBBBE is a derivatized fluorescein compound that is used to detect the production hydrogen peroxide (H2O2) by cells. Intracellular H2O2, but not extracellular H2O2, initiates the conversion of FBBBE to fluorescein, resulting in an increase in intracellular fluorescence (excitation/emission maxima: 480/512 nm).
价 格:¥电议型 号:T38165产 地:中国大陆
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T371658-iso Prostaglandin F2β;8-iso Prostaglandin F2β8-iso Prostaglandin F2β;8-iso Prostaglandin F2β
8-iso Prostaglandin F2β can be used in related research in the field of life sciences. Its product number is T37165 and CAS number is 177020-26-7.
价 格:¥电议型 号:T37165产 地:中国大陆