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T368663-Deazauridine;4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮NSC 126849;4-羟基-1-Β-D-呋喃核糖苷-2(1H)吡啶酮|||NSC 126849
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5´-Triphosphate by competitive inhibition of Cytidine Triphosphate synthetase which is considered to be the primary mode of action of this nucleoside analog.
价 格:¥电议型 号:T36866产 地:中国大陆
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T36865Heat Shock Protein Inhibitor II;Heat Shock Protein Inhibitor IIHeat Shock Protein Inhibitor II
Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of A
价 格:¥电议型 号:T36865产 地:中国大陆
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T36864GRP (human) (trifluoroacetate salt);GRP (human) (trifluoroacetate salt)GRP (human) (trifluoroacetate
Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM.
价 格:¥电议型 号:T36864产 地:中国大陆
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T36863Geranylgeranyl Pyrophosphate (ammonium salt);Geranylgeranyl Pyrophosphate (ammonium salt)Geranylgera
Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids.[1] It is also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.[2] This post-translational modification is necessary for correct localization of proteins to intracellular membranes for proper functionality and has become a focus of anticancer drug disco
价 格:¥电议型 号:T36863产 地:中国大陆
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T36862Ganglioside GT1b Mixture (sodium salt);Ganglioside GT1b Mixture (sodium salt)Ganglioside GT1b Mixtur
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 μM, respectively.[1] Ganglioside GT1b-containing liposomes bind to the major coat protein VP1 from Merkel cell polyomavirus (MCPyV), which has been identified in Merkel cell carcinomas, identifying ganglioside GT1b as a putative MCP
价 格:¥电议型 号:T36862产 地:中国大陆
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T36861Ganglioside GD1b Mixture (sodium salt);Ganglioside GD1b Mixture (sodium salt)Ganglioside GD1b Mixtur
Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside
价 格:¥电议型 号:T36861产 地:中国大陆
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T36860C22 Sphingomyelin (d18:1/22:0);C22 Sphingomyelin (d18:1/22:0)C22 Sphingomyelin (d18:1/22:0);C22 Sphi
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyelin levels are decreased in T-47D mammary epithelial cells and increased in MDA-MB-231 breast cancer cells relative to C16 sphingomyelin .
价 格:¥电议型 号:T36860产 地:中国大陆
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T368610074-G5;化合物10074-G510074-G5
10074-G5 is an inhibitor of c-Myc-Max dimerization.
价 格:¥电议型 号:T3686产 地:中国大陆
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T356863-Acetyl Betulinaldehyde3-Acetyl Betulinaldehyde3Acetyl Betulinaldehyde|||3 Acetyl Betulinaldehyde
3-Acetyl betulinaldehyde is a triterpene and derivative of the cholesterol biosynthesis inhibitor betulin that has been found inA. japonica.1It is an intermediate in the synthesis of 3-acetylbetulinic acid, as well as various lupine and germanicane triterpenes and saponins with anticancer activity.2
价 格:¥电议型 号:T35686产 地:中国大陆
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T35325Lα-Conotoxin GI acetate;化合物α-Conotoxin GI acetateα-Conotoxin GI acetate (76862-65-2 Free base);α-Cono
α-Conotoxin GI acetate?is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR).
价 格:¥电议型 号:T35325L产 地:中国大陆
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T3492PD-166866;化合物PD166866PD166866;PD166866
PD-166866 is a selective FGFR tyrosine kinase inhibitor.
价 格:¥电议型 号:T3492产 地:中国大陆
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T34686Sonoflora 1;化合物 T34686SF 1|||SF-1|||Sonoflora1|||Sonoflora-1|||SF1;SF 1|||SF-1|||Sonoflora1|||Sonofl
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Preclinical studies showed that SF1 had very high sonodynamic as well as photodynamic activity. The clinically tested results demonstrated positive therapeutic effects for treating patients with advanced refractory breast cancers that had failed to respond to conventional chemotherapy.
价 格:¥电议型 号:T34686产 地:中国大陆
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T33686Nitrocaphane;化合物 T33686AT 1258|||AT-1258|||AT1258;AT 1258|||AT-1258|||AT1258
Nitrocaphane, in combination with 5-FU (fluorouracil), chemotherapy is considered as a protocol of choice in the treatment of malignant trophoblastic tumor.
价 格:¥电议型 号:T33686产 地:中国大陆
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T33421MK-0686;化合物MK-0686MK0686;MK0686
MK-0686 is an orally available bradykinin B1 receptor antagonist with potential anti-inflammatory activity.
价 格:¥电议型 号:T33421产 地:中国大陆
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T32686Leustroducsin A;化合物 T32686LSN A;LSN A
Leustroducsin A is an inducer of colony-stimulating factors (CSFs) extracted from Streptomyces platensis SANK 60191.
价 格:¥电议型 号:T32686产 地:中国大陆
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T32466L 686741;化合物 T32466L-686741|||L686741|||L 686,741|||L686,741|||L-686,741;L-686741|||L686741|||L 686,
L 686741 is a bioactive chemical.
价 格:¥电议型 号:T32466产 地:中国大陆
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T30686LCafedrine HCl;化合物 T30686LCafedrine hydrochloride|||Akrinor|||L-Net;Cafedrine hydrochloride|||Akrinor
Cafedrine HCl is a chemical linkage of norephedrine and theophylline.
价 格:¥电议型 号:T30686L产 地:中国大陆
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T30686Cafedrine;去甲麻黄茶碱l-Cafedrine|||Cafedrin;l-Cafedrine|||Cafedrin
Cafedrine (Cafedrin) is found in tea and coffee and has a central nervous system stimulant effect.Cafedrine is often used in a 20:1 combination with a fixed dose of cortisone in the study of acute hypotension.
价 格:¥电议型 号:T30686产 地:中国大陆
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T30137ARN14686化合物 T30137ARN-14686|||ARN14686
ARN14686 is an activity-based affinity probe for the detection of N-acylethanolamine acid amidase (NAAA) using click chemistry.
价 格:¥电议型 号:T30137产 地:中国大陆
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T29686AF53;化合物 T29686AF 53|||AF-53;AF 53|||AF-53
AF53 is an kind of alpha-L-arabinofuranosidase containing a noncatalytic xylan-binding domain.
价 格:¥电议型 号:T29686产 地:中国大陆