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  • T8528AC1903；化合物AC1903AC1903

    AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.

    价 格：￥电议型 号：T8528产 地：中国大陆

  • T84314BFC1108；化合物 BFC1108BFC1108

    产品可用于生物细胞实验

    价 格：￥电议型 号：T84314产 地：中国大陆

  • T83974OPC18750 HCl；化合物 OPC18750 HClOPC18750 HCl

    OPC18750 HCl is a potential phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.

    价 格：￥电议型 号：T83974产 地：中国大陆

  • T83921IMCTA-C14 TFA；化合物 IMCTA-C14 TFAIMCTA-C14 TFA

    IMCTA-C14, a detergent and derivative of the microbial metabolite 4-trehalosamine, exhibits a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. It effectively extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells at concentrations of 0.05 and 0.5%. Furthermore, IMCTA-C14 demonstrates antibacterial activity against various bacterial strains (MICs = 8-128 ?g/ml) and shows cytotoxicity against a spectrum of 52 cancer

    价 格：￥电议型 号：T83921产 地：中国大陆

  • T83880C18 Ceramide-1-phosphate (d18:1/18:0) ammonium；化合物 C18 Ceramide-1-phosphate (d18:1/18:0) ammoniumCer

    C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin known to promote the migration of mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells (HUVECs) at concentrations of 0.5 to 5 ?M. It exhibits elevated levels in CFPAC-1 pancreatic ductal adenocarcinoma cells compared to pancreatic cancer stem cells, and its myocardial concentration is heightened in Langendorff isolated perfused mouse hearts under an ex vivo ischemia

    价 格：￥电议型 号：T83880产 地：中国大陆

  • T83842LHC165 hydrate；化合物 LHC165 hydrateLHC165 hydrate

    LHC165, a toll-like receptor 7 (TLR7) agonist, stimulates the immune system´s response by activating TLR7.

    价 格：￥电议型 号：T83842产 地：中国大陆

  • T82992AP-C1；化合物 AP-C1AP-C1

    AP-C1 is a potent inhibitor of cGMP-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 6.5, yet it only weakly inhibits cGKII-dependent anion secretion [1].

    价 格：￥电议型 号：T82992产 地：中国大陆

  • T82801C12 NBD Galactosylceramide；化合物 C12 NBD GalactosylceramideC12 NBD Galactosylceramide

    C12 NBD Galactosylceramide, a fluorescent dye-labeled variant of galactosylceramide, possesses a C12 nitrobenzoxadiazole (C12 NBD) moiety that enables fluorescence. This compound serves as a tool in imaging research [1].

    价 格：￥电议型 号：T82801产 地：中国大陆

  • T82800C12-NBD-ceramide；化合物 C12-NBD-ceramideC12-NBD-ceramide

    C12-NBD-ceramide, a fluorescent analogue of ceramide, serves as a substrate in ceramidase assays [1] [2].

    价 格：￥电议型 号：T82800产 地：中国大陆

  • T82713Ciwujianoside C1；化合物 Ciwujianoside C1Ciwujianoside C1

    Ciwujianoside C1, a saponin derived from the leaves of Acanthopanax senticosus, exhibits in vitro inhibition of pancreatic lipase activity [1].

    价 格：￥电议型 号：T82713产 地：中国大陆

  • T82572D-Glucosyl-β-1,1′-N-palmitoylsphingosine；化合物 D-Glucosyl-β-1,1′-N-palmitoylsphingosineC16 Glucosyl(β)

    D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) serves as an endogenous ligand for the Macrophage-Inducible C-type Lectin (Mincle), exhibiting immunostimulatory properties [1].

    价 格：￥电议型 号：T82572产 地：中国大陆

  • T82546DiSBAC10；化合物 DiSBAC10DiSBAC10

    DiSBAC10, a voltage-sensitive fluorescent probe, facilitates cell membrane electrical activity investigation in FRET assays. At rest, it populates the membrane´s outer leaflet, accepting photons from excited fluorescein-labeled proteins and emitting them at higher wavelengths. Upon cell depolarization, DiSBAC10 quickly translocates to the inner leaflet, increasing fluorophore separation and diminishing the FRET signal.

    价 格：￥电议型 号：T82546产 地：中国大陆

  • T82227HDAC1/CDK7-IN-1；化合物 HDAC1/CDK7-IN-1HDAC1/CDK7-IN-1

    HDAC1/CDK7-IN-1 (compound 8e) serves as a dual inhibitor targeting both CDK7 and HDAC1, with IC50 values of 893 nM and 248 nM , respectively. This compound effectively suppresses the proliferation of various cancer cell lines, including MDA-MB-231, MCF-7, A549, and HCT-116. Additionally, it triggers cell cycle arrest and apoptosis in HCT-116 cells and impedes their migration [1].

    价 格：￥电议型 号：T82227产 地：中国大陆

  • T82043Iso5-2DC18；化合物 Iso5-2DC18Iso5-2DC18

    Iso5-2DC18, a lipid, is utilized in the synthesis of amine-containing lipids, which are instrumental in mRNA delivery, activation of the stimulator of interferon genes (STING) pathway, and demonstration of anti-tumor immunity [1].

    价 格：￥电议型 号：T82043产 地：中国大陆

  • T81895Lysophosphatidylcholine C19:0；化合物 Lysophosphatidylcholine C19:01-Nonadecanoyl-2-hydroxy-sn-glycero-3

    Lysophosphatidylcholine C19:0 (1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine), an acyl chain lipid, enhances IL-1beta secretion [1].

    价 格：￥电议型 号：T81895产 地：中国大陆

  • T81823Mem-C1C18；化合物 Mem-C1C18Mem-C1C18

    Mem-C1C18, a polarity-sensitive fluorescent probe, exhibits superior plasma membrane anchoring and high brightness, alongside a sensitive alteration in fluorescence lifetime in response to environmental polarity changes. This compound facilitates the quantification of plasma membrane polarity fluctuations during ferroptosis [1].

    价 格：￥电议型 号：T81823产 地：中国大陆

  • T81743mTORC1-IN-1；化合物 mTORC1-IN-1mTORC1-IN-1

    mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseases such as cancer. It interacts with mTORC1 by attaching to the FKBP12-FRB complex, evidencing a docking score of -11.6 kcal/mol [1].

    价 格：￥电议型 号：T81743产 地：中国大陆

  • T81722N-(3-Oxodecanoyl)-L-homoserine lactone；化合物 N-(3-Oxodecanoyl)-L-homoserine lactone3-Oxo-C10-HSL；3-Oxo

    N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) functions as a bacterial quorum-sensing signal autoinducer [1].

    价 格：￥电议型 号：T81722产 地：中国大陆

  • T81640NSC15520；化合物 NSC15520NSC15520

    NSC15520, a small-molecule inhibitor of Replication Protein A (RPA), selectively targets the N-terminal DNA binding domain (DBD) of RPA, preventing its interaction with p53 and RAD9. Additionally, NSC15520 impedes the helix destabilization of duplex DNA (dsDNA) oligonucleotides, playing a role in processes such as DNA replication, repair, recombination, and the DNA damage response signaling pathway [1].

    价 格：￥电议型 号：T81640产 地：中国大陆

  • T80919Tumour-associated MUC1 epitope；化合物 Tumour-associated MUC1 epitopeTumour-associated MUC1 epitope

    Tumor-associated MUC1 epitope, a biologically active peptide, is the distinctive feature of MUC1 mucin—a significantly glycosylated type I transmembrane glycoprotein. Its extracellular domain comprises variable numbers of tandem repeats (VNTR) of a 20 amino acid sequence. This peptide is overexpressed on the surface of various human adenocarcinomas and hematological malignancies like multiple myeloma and B-cell lymphoma, rendering MUC1 a widely relevant target for immunotherapeutic approaches.

    价 格：￥电议型 号：T80919产 地：中国大陆

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