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T80873VEGFR2/HDAC1-IN-1;化合物 VEGFR2/HDAC1-IN-1VEGFR2/HDAC1-IN-1
VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC. It arrests the cell cycle at the S and G2 phases and induces apoptosis in HeLa cells, demonstrating an anti-angiogenic effect [1].
价 格:¥电议型 号:T80873产 地:中国大陆
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T80256C18G;化合物 C18GC18G
C18G, a synthetic α-helical peptide derived from human platelet factor IV, exhibits biological activity with pronounced antibacterial properties against Salmonella.
价 格:¥电议型 号:T80256产 地:中国大陆
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T80178Dc1a;化合物 Dc1aDc1a
Dc1a, a toxin isolated from the desert bush spider Diguetia canities [1], potently facilitates the opening of the German cockroach Na v channel (BgNa v 1).
价 格:¥电议型 号:T80178产 地:中国大陆
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T79869Rac1-IN-3;化合物 Rac1-IN-3Rac1-IN-3
Rac1-IN-3 (Compound 2) is a Rac1 inhibitor exhibiting an inhibitory concentration 50 (IC50) of 46.1 μM [1].
价 格:¥电议型 号:T79869产 地:中国大陆
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T78626LY393615;化合物 LY393615NCC1048;NCC1048
LY393615 (NCC1048) is a novel blocker of both neuronal Ca?? (calcium) and Na? (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC??) of 1.9 ?M and 5.2 ?M against α1A and α1B calcium channel subunits, respectively. This compound demonstrates effective brain penetration and has shown neuroprotective effects in cerebral ischemia models, suggesting its utility in neurological disease research [1].
价 格:¥电议型 号:T78626产 地:中国大陆
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T78473Sphingosine (d17:1);化合物 Sphingosine (d17:1)C17 Sphingosine;C17 Sphingosine
Sphingosine (d17:1) (C17 Sphingosine) is a 17-carbon sphingolipid found in human skin that can be phosphorylated by sphingomyelin kinase.Sphingosine C-17 can be used as an internal standard to perform spectroscopic analysis of sphingolipids.
价 格:¥电议型 号:T78473产 地:中国大陆
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T78393C12FDG;化合物 C12FDG5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside;5-Dodecanoylaminofluorescein
C12FDG (5-Dodecanoylaminofluorescein di-beta-D-Galactopyranoside) is used as a lipophilic green fluorescent substrate for detecting beta-galactose activity, a green fluorescent substrate, is a senescence marker and is often used in conjunction with flow cytometry.
价 格:¥电议型 号:T78393产 地:中国大陆
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T78309Telitacicept;化合物 TelitaciceptRC18;RC18
Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand), effectively impeding B lymphocyte proliferation. This compound is applicable in researching B-cell autoimmune diseases [1].
价 格:¥电议型 号:T78309产 地:中国大陆
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T78210STC-15;化合物STC-15STC15;STC15
STC-15 is an orally active and potent METTL3 inhibitor with anticancer activity that inhibits cancer growth and induces anticancer immunity.
价 格:¥电议型 号:T78210产 地:中国大陆
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T78203NSC194598;化合物 NSC194598NSC194598
NSC194598 is a p53 DNA-binding inhibitor, demonstrating an in vitro IC50 of 180 nM and an in vivo range of 2-40 μM. It disrupts the transcriptional activation of the mutated RET gene in human medullary thyroid carcinoma TT cells. The compound is utilized in research investigating acute toxicity in normal tissues due to radiation and chemotherapy [1] [2].
价 格:¥电议型 号:T78203产 地:中国大陆
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T78191NH2-C6-ARC186;化合物 NH2-C6-ARC186NH2-C6-ARC186
NH2-C6-ARC186 is a derivative of the aptamer ARC186, featuring an NH2-C6 moiety that enables coupling to various peptides or molecules. As a potent complement inhibitor, it operates by inhibiting convertase-mediated C5 activation [1].
价 格:¥电议型 号:T78191产 地:中国大陆
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T78179NH2-UAMC1110 TFA;化合物 NH2-UAMC1110 TFANH2-UAMC1110 TFA
NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating agent crucial for creating radiotracers with high tumor selectivity and potency for tumor diagnosis and therapy [1] [2].
价 格:¥电议型 号:T78179产 地:中国大陆
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T78145HDAC10-IN-2 hydrochloride;化合物 HDAC10-IN-2 hydrochlorideHDAC10-IN-2 hydrochloride
HDAC10-IN-2 hydrochloride (compound 10c) is an HDAC10 inhibitor with high potency and selectivity, exhibiting an IC50 of 20 nM. It influences autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1].
价 格:¥电议型 号:T78145产 地:中国大陆
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T78105PAC1R antagonist 1;PAC1 拮抗剂1PAC1R antagonist 1
PAC1R antagonist 1 is an orally active PAC1 receptor antagonist that inhibits abnormal pain induced by pituitary adenylate cyclase-activating polypeptide (PACAP) and nerve damage, and may be used in the study of neoplasms and immune-related disorders.
价 格:¥电议型 号:T78105产 地:中国大陆
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T77984Thalidomide-NH-C10-NH2 hydrochloride;化合物 Thalidomide-NH-C10-NH2 hydrochlorideThalidomide-NH-C10-NH2
Thalidomide-NH-C10-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates CRBN protein recruitment and, when conjugated with a linker, forms PROTACs [1].
价 格:¥电议型 号:T77984产 地:中国大陆
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T77982Pomalidomide-5-C12-NH2 hydrochloride;化合物 Pomalidomide-5-C12-NH2 hydrochloridePomalidomide-5-C12-NH2
Pomalidomide-5-C12-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be conjugated to a protein-targeting ligand via a linker to create a PROTAC [1].
价 格:¥电议型 号:T77982产 地:中国大陆
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T77981Pomalidomide-5-C11-NH2 hydrochloride;化合物 Pomalidomide-5-C11-NH2 hydrochloridePomalidomide-5-C11-NH2
Pomalidomide-5-C11-NH2 hydrochloride is a Pomalidomide-derived cereblon (CRBN) ligand that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a protein ligand via a linker to create a PROTAC [1].
价 格:¥电议型 号:T77981产 地:中国大陆
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T77980Pomalidomide-5-C10-NH2 hydrochloride;化合物 Pomalidomide-5-C10-NH2 hydrochloridePomalidomide-5-C10-NH2
Pomalidomide-5-C10-NH2 hydrochloride, a Pomalidomide-derived cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. This compound can be tethered to a protein ligand via a linker to construct a PROTAC [1].
价 格:¥电议型 号:T77980产 地:中国大陆
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T77971Pomalidomide-C11-NH2 hydrochloride;化合物 Pomalidomide-C11-NH2 hydrochloridePomalidomide-C11-NH2 hydroc
Pomalidomide-C11-NH2 hydrochloride is a cereblon (CRBN) ligand derived from Pomalidomide used to recruit the CRBN protein. This compound can be conjugated with a linker to the protein ligand to assemble a PROTAC [1].
价 格:¥电议型 号:T77971产 地:中国大陆
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T77964Thalidomide-4-O-C14-NH2 hydrochloride;化合物 Thalidomide-4-O-C14-NH2 hydrochlorideThalidomide-4-O-C14-N
Thalidomide-4-O-C14-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, through the attachment of a linker, can be utilized to create PROTACs [1].
价 格:¥电议型 号:T77964产 地:中国大陆