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T6946Pimavanserin tartrateInhibitor,Pimavanserin hemitartrate,5-hydroxytryptamine Receptor,ACP-103 hemita
Pimavanserin is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson´s disease.
价 格:¥电议型 号:T6946产 地:中国大陆
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T9430Venadaparibinhibit,PARP,Venadaparib,IDX1197,Inhibitor,solid,IDX 1197,tumors,anticancer,poly ADP ribo
Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSBs) and can be used in solid tumor research.
价 格:¥电议型 号:T9430产 地:中国大陆
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T9346CVN424penetrant,CVN 424,GPR6,inhibit,orally,CVN424,brain,Inhibitor,Parkinson,CVN-424,disease
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
价 格:¥电议型 号:T9346产 地:中国大陆
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T73792-D08Ubiquitin ligase,Axl,2-D08,Tyro3,E3 ligating enzyme,Ubiquitin activating enzyme,Inhibitor,E1 ac
2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.
价 格:¥电议型 号:T7379产 地:中国大陆
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T6670Silymarinthistle,angiogenesis,Inhibitor,hepatocellular,resistance,SARS coronavirus,chemopreventive,i
Silymarin (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
价 格:¥电议型 号:T6670产 地:中国大陆
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TQ0248Alisol FInhibitor,Alisol F,immunosuppressive,triterpene,Hepatitis B virus,HBV,inhibit,virus
Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities.
价 格:¥电议型 号:TQ0248产 地:中国大陆
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T8308NL-1Inhibitor,viability,Mitochondrial Metabolism,leukemia,NL-1,CISD1,NL1,antileukemic,MitoNEET,lymph
NL-1 is a mitoNEET inhibitor with antileukemic effect.
价 格:¥电议型 号:T8308产 地:中国大陆
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T9023AtuliflaponInhibitor,inhibit,FLAP,AZD-5718,AZD 5718,artery,Atuliflapon,disease,Coronary,5-LO activat
AZD5718 is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease.
价 格:¥电议型 号:T9023产 地:中国大陆
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T9167PF-9363CTx-648,cancer,patient-derived,anti-tumor,HAT,CTx648,Inhibitor,HATs,selective,xenograft,CTx 6
PF-9363 is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.
价 格:¥电议型 号:T9167产 地:中国大陆
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T6686Sulconazole mononitrateanaerobes,antimicrobial,Inhibitor,Fungal,antibacterial,Bacterial,Gram-positiv
Sulconazole Nitrate is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole nitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and inhibition of the synthesis of ergosterol, an important component of the fungal cell membrane. Inhibition of ergosterol synthesis leads to a disruption of cell membrane permeability, and ultimately inhibition of cell wall
价 格:¥电议型 号:T6686产 地:中国大陆
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T6410Bexarotenecutaneous,lymphoma,selective,?retinoid,inhibit,Retinoic acid receptors,antineoplastic,T-ce
Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
价 格:¥电议型 号:T6410产 地:中国大陆
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T6725VU 0357121inhibit,VU-0357121,VU 0357121,VU0357121,Inhibitor,Metabotropic glutamate receptors,mGluR
VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.
价 格:¥电议型 号:T6725产 地:中国大陆
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T15612JH-VIII-157-02CD246,Cluster of differentiation 246,inhibit,Anaplastic lymphoma kinase,Anaplastic lym
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.
价 格:¥电议型 号:T15612产 地:中国大陆
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T60081BV02
BV02 is an inhibitor of 14-3-3 protein-protein interactions and can be used in studies about the treatment of chronic myeloid leukemia. BV02 disrupts hematopoietic cells expressing the IM-resistant T315I mutation and the IM-sensitive wild-type Bcr-Abl.
价 格:¥电议型 号:T60081产 地:中国大陆
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T39668Methyl propyl disulfideMethyl propyl disulfide,anticaner,GST-P,inhibit,Inhibitor,volatile,Sulfur-con
Methyl propyl disulfide is a natural compound containing volatile sulfur produced in garlic and onions. Methyl propyl disulfide displays an anticaner effect.
价 格:¥电议型 号:T39668产 地:中国大陆
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T9230KM 91104V-ATPase human HSC,a3-b2 subunits,KM-91104,KM 91104,Inhibitor,KM91104,Proton Pump,cell-perme
KM 91104 is a cell permeable inhibitor of V-ATPase. KM91104 specifically targets the interaction between V-ATPase subunit A3 and subunit B2.
价 格:¥电议型 号:T9230产 地:中国大陆
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TN2283Tripterifordininhibit,HIV,Human immunodeficiency virus,replication,Tripterifordin,anti-HIV,Inhibitor
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
价 格:¥电议型 号:TN2283产 地:中国大陆
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T9989WAY-298592neurological diseases,alzheimer’s disease,WAY 298592,Inhibitor,dementia,myasthenia gravis,
WAY-298592 is a small molecule used for high-throughput assays.
价 格:¥电议型 号:T9989产 地:中国大陆
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T6446ClevudineOrthopoxvirus,half-life,nucleoside,DNA/RNA Synthesis,analog,Inhibitor,polymerase,Hepatitis
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DN
价 格:¥电议型 号:T6446产 地:中国大陆
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T16873SERCA2a activator 1Ca channels,phospholamban,Inhibitor,Ca2+ channels,SERCA2a activator 1,SERCA2a,SER
SERCA2a activator 1 is a sarco/endoplasmic reticulum Ca2+-dependent ATPase 2a activator. SERCA2a activator 1 decreases phospholamban inhibition and enhances the systolic and diastolic functions of the heart.
价 格:¥电议型 号:T16873产 地:中国大陆