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T71127Ipconazole [ISO];化合物 Ipconazole [ISO]Ipconazole [ISO]
Ipconazole is a member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl, 4-chlorobenzyl and isopropyl substituents at positions 1, 2 and 5 respectively. Used to control a range of seed diseases in rice, vegetables and other, mainly non-food, crops. It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of cyclopentanols, a member of monochlorobenzenes, a member of triazoles, a tertiary alcohol, a conazole fungicide
价 格:¥电议型 号:T71127产 地:中国大陆
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T71126Allixin;化合物 AllixinAllixin
Allixin is a phytoallexin found in garlic (Allium sativum) bulbs. Allixin has weak antimicrobial activity and exerts an anti-promoting activity against skin tumors induced by the chemical 12-O-tetradecanoylphorbol-13-acetate (TPA). Allixin also demonstrates an inhibitory effect on aflatoxin B1-induced mutagenesis.
价 格:¥电议型 号:T71126产 地:中国大陆
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T71125Ro-31-7549 Monohydrate;化合物 Ro-31-7549 MonohydrateRo-31-7549 Monohydrate
Ro-31-7549 Monohydrate is a cell permeable, reversible, selective protein kinase C (PKC) inhibitor.
价 格:¥电议型 号:T71125产 地:中国大陆
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T71124NNC 112;化合物 NNC 112NNC 112
NNC 112 is a selective dopamine D1 receptor antagonists.
价 格:¥电议型 号:T71124产 地:中国大陆
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T71123RG 12915;化合物 RG 12915RG 12915
RG 12915 is a potent, selective 5-HT3 receptor antagonist developed for the treatment of emesis and nausea associated with cancer chemotherapy.
价 格:¥电议型 号:T71123产 地:中国大陆
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T71122Carsatrin (free base);化合物 Carsatrin (free base)Carsatrin (free base)
Carsatrin is purinylpiperazine derivative. as cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbine, or prazosin
价 格:¥电议型 号:T71122产 地:中国大陆
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T71120AR-13503;化合物 AR-13503AR-13503
AR-13503, is an metabolite of Netarsudil (AR-11324), is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and?/or reducing intraocular pressure.
价 格:¥电议型 号:T71120产 地:中国大陆
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T7112Ibutamoren Mesylate;伊布莫仑甲磺酸盐MK-0677|||MK-677;MK-0677|||伊布莫仑甲磺酸盐|||MK-677
Ibutamoren Mesylate (MK-0677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist.
价 格:¥电议型 号:T7112产 地:中国大陆
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T71112SAR156497;化合物 SAR156497SAR156497
SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A); 1 nM (Aurora B / incenp); 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP 3A4 and PDE3 inhibition. In vitro, SAR156497 displayed high antiproliferative activity on a large panel of tumor cell lines without correlation with any particular genetic signature or Aurora kinases expressi
价 格:¥电议型 号:T71112产 地:中国大陆
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T70749TY 11223;化合物 TY 11223TY 11223
TY 11223 is a chemically stable homoisocarbacyclin analog. It has showed potent and long-lasting activities in inhibiting platelet aggregation and a good selectivity in biological activities.
价 格:¥电议型 号:T70749产 地:中国大陆
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T70528GR-112000;化合物 GR-112000GR-112000
GR-112000 is a peptide-based tachykinin NK2 receptor antagonist.
价 格:¥电议型 号:T70528产 地:中国大陆
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T70510CVS-1123;化合物 CVS-1123CVS-1123
CVS-1123 is a direct thrombin inhibitor, preventing occlusive arterial and venous thrombosis in a canine model of vascular injury.
价 格:¥电议型 号:T70510产 地:中国大陆
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T70431TX-1123;化合物 TX-1123TX-1123
TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 μM for COX2 and 15.7 μM for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.
价 格:¥电议型 号:T70431产 地:中国大陆
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T70362V11294A;化合物 V11294AV11294A
V11294A is a novel PDE4 inhibitor. A single oral 300 mg dose of V11294A administered to healthy volunteers results in plasma concentrations adequate to inhibit activation of inflammatory cells ex vivo, which persists for at least 24 h without any adverse reactions
价 格:¥电议型 号:T70362产 地:中国大陆
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T70112GT-2227;化合物 GT-2227GT-2227
GT-2227 is a histamine H3 receptor antagonist.
价 格:¥电议型 号:T70112产 地:中国大陆
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T6965RG7112;化合物RG7112RG-7112|||RG 7112|||RO5045337;RG-7112|||RG 7112|||RO5045337
RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.
价 格:¥电议型 号:T6965产 地:中国大陆
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T69498DBPR112 HCl;化合物 DBPR112 HClDBPR112 HCl
DBPR112 is a potent EGFR inhibitor (IC50=487 nM) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer. DBPR112), DBPR112not only displayed a potent inhibitory activity against EGFRL858R/T790M double mutations but also exhibited tenfold potency better than the third-generation inhibitor, osimertinib,against EGFR and HER2 exon 20 insertion mutations. Overall, pharmacokinetic improvement through lead-to-candidateoptimization yielded fourfold oral AUC better that afatinib along wi
价 格:¥电议型 号:T69498产 地:中国大陆
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T69272AM-112;化合物 AM-112AM-112
AM-112 is an Oxapenem compound which possesses potent beta-lactamase-inhibitory properties.
价 格:¥电议型 号:T69272产 地:中国大陆
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T69112Pyrvinium chloride;化合物 Pyrvinium chloridePyrvinium chloride
Pyrvinium chloride is used in the treatment of pinworm infections
价 格:¥电议型 号:T69112产 地:中国大陆