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T68901SU11271;化合物 SU11271SU11271
SU11271 is a potent c-MET inhibitor with potential anticancer activity.
价 格:¥电议型 号:T68901产 地:中国大陆
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T68758UNC10112785;化合物 UNC10112785UNC10112785
UNC10112785 is a novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth, inducing the substantial loss of MYC protein in both two-dimensional (2D) and 3D cell cultures.
价 格:¥电议型 号:T68758产 地:中国大陆
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T68112Nafimidone;萘咪酮Nafimidone
Nafimidone shows anticonvulsant activity in a rat model of amygdala epilepsy and can be used in the treatment of chronic intractable epilepsy.
价 格:¥电议型 号:T68112产 地:中国大陆
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T67112(R)-5,7-Difluorochroman-4-ol;化合物 (R)-5,7-Difluorochroman-4-ol(R)-5,7-Difluorochroman-4-ol
(R)-5,7-Difluorochroman-4-ol is a useful organic compound for research related to life sciences. The catalog number is T67112 and the CAS number is 1270294-05-7.
价 格:¥电议型 号:T67112产 地:中国大陆
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T6672Sitaxsentan sodium;西他生坦钠TBC11251 sodium salt|||TBC11251|||Thelin|||Sitaxentan sodium;西他生坦钠|||TBC1125
Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.
价 格:¥电议型 号:T6672产 地:中国大陆
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T66657VUF11207 trifluoroacetate salt;化合物 VUF11207 trifluoroacetate saltVUF11207 trifluoroacetate salt
VUF11207 trifluoroacetate salt is a useful organic compound for research related to life sciences. The catalog number is T66657 and the CAS number is 1378524-41-4.
价 格:¥电议型 号:T66657产 地:中国大陆
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T66112Z-D-Arg-OH;化合物 Z-D-Arg-OHZ-D-Arg-OH
Z-D-Arg-OH is an amino acid derivative and has a wide range of applications in life science related research.
价 格:¥电议型 号:T66112产 地:中国大陆
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T65112Dibutylsulfide;化合物 DibutylsulfideDibutylsulfide
Dibutylsulfide is a useful organic compound for research related to life sciences. The catalog number is T65112 and the CAS number is 544-40-1.
价 格:¥电议型 号:T65112产 地:中国大陆
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T64197Antibacterial agent 112;化合物 Antibacterial agent 112Antibacterial agent 112
Antibacterial agent 112 (compound 2) is a potent antibacterial agent. subtilis (MIC: 1250 μM), E. coli (MIC: 1250 μM), E. faecalis (MIC: 1250 μM), S. typhimuriumand (MIC: 1250 μM) and S. aureus microorganisms (MIC: 1250 μM). A3N19 is an HIV-1 antibody with antibacterial activity.
价 格:¥电议型 号:T64197产 地:中国大陆
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T64112HIV-1 protease-IN-5;化合物 HIV-1 protease-IN-5HIV-1 protease-IN-5
HIV-1 protease-IN-5 is an HIV-1 protease inhibitor (IC50: 1.64 nM). HIV-1 protease-IN-5 exhibits significant effects on wild-type and DRV-resistant HIV-1.
价 格:¥电议型 号:T64112产 地:中国大陆
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T63228Simmiparib;希明哌瑞SMOCL-9112;SMOCL-9112
Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR)-deficient cells, thereby contributing to apoptosis.Simmiparib has been used for study Parkinson´s disease, Alzheimer´s disease, breast cancer, and melanoma.
价 格:¥电议型 号:T63228产 地:中国大陆
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T63112VEGFR-IN-3;化合物 VEGFR-IN-3VEGFR-IN-3
VEGFR-IN-3 (compound 3f), a VEGFR inhibitor, exhibits potent anticancer activity by inhibiting the growth of OVCAR-4 and MDA-MB-468 cancer cells with IC50 values of 0.29 and 0.35 μM, respectively. It has potential applications in cancer research [1].
价 格:¥电议型 号:T63112产 地:中国大陆
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T6305SNX2112;化合物SNX2112SNX-2112|||PF 04928473|||SNX 2112;SNX-2112|||PF 04928473|||SNX 2112
SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.
价 格:¥电议型 号:T6305产 地:中国大陆
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T62385Befiradol hydrochloride;化合物 Befiradol hydrochlorideNLX-112 hydrochloride|||F 13640 hydrochloride;NLX
Befiradol hydrochloride (NLX-112 hydrochloride) is a selective 5-hydroxytryptamine 1A (5-HT)1A receptor agonist with anxiolytic activity.Befiradol hydrochloride inhibits mutant ATXN3 aggregation.
价 格:¥电议型 号:T62385产 地:中国大陆
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T62112CDK8-IN-6;化合物 CDK8-IN-6CDK8-IN-6
CDK8-IN-6 (compound 9) is a potent inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 13 nM), CDK8-IN-6 showed potential research value in AML cancers.
价 格:¥电议型 号:T62112产 地:中国大陆
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T6154SU11274;化合物SU11274Met Kinase Inhibitor|||PKI-SU11274;Met Kinase Inhibitor|||PKI-SU11274
SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.
价 格:¥电议型 号:T6154产 地:中国大陆
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T61268Vutiglabridin;化合物VutiglabridinHSG4112;HSG4112
Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stability. vutiglabridin ameliorates mptp-induced neurodegeneration in Parkinson´s disease mice by targeting mitochondrial paraoxonase-2. Vutiglabridin is a clinical phase 2 drug for the treatment of obesity and has therapeutic effects on p-mitochondrial PON2 in a PD model. vutigla
价 格:¥电议型 号:T61268产 地:中国大陆
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T61129Tubulin polymerization-IN-27;化合物 Tubulin polymerization-IN-27Tubulin polymerization-IN-27
Tubulin polymerization-IN-27 (compound 5j) is an inhibitor of tubulin polymerization. It has the ability to halt the cell cycle specifically at the G2/M phase and also induce apoptosis [1].
价 格:¥电议型 号:T61129产 地:中国大陆
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T61128c-ABL-IN-2;化合物 c-ABL-IN-2c-ABL-IN-2
C-ABL-IN-2 is a highly effective inhibitor of the c-Abl protein, which plays a significant role in the development of several diseases, including cancer. This compound exhibits promise for investigating neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS) and Parkinson´s disease (PD), as well as cancer. (Source: WO2020260871A1, compound 25) [1].
价 格:¥电议型 号:T61128产 地:中国大陆
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T61126Antibacterial synergist 1;化合物 Antibacterial synergist 1Antibacterial synergist 1
Antibacterial synergist 1 (compound 20P) is a potent inhibitor of bacterial biofilm formation. It effectively suppresses the production of pyocyanin, with an IC 50 of 8.6 μM, and inhibits biofilm formation with an IC 50 of 4.5 μM. Antibacterial synergist 1 shows promise in the research of P. aeruginosa infections [1].
价 格:¥电议型 号:T61126产 地:中国大陆