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  • T14716Boc-Aminooxy-PEG3-thiol;化合物 T14716Boc-Aminooxy-PEG3-thiol

    Boc-Aminooxy-PEG3-thiol is a polyethylene glycol (PEG)-based PROTAC linker, employed for the synthesis of PROTACs[1].

    价 格:¥电议型 号:T14716产 地:中国大陆

  • T14706Boc-Aminooxy-PEG1-azide;化合物 T14706Boc-Aminooxy-PEG1-azide

    Boc-Aminooxy-PEG1-azide is a polyethylene glycol (PEG) derived linker compound designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

    价 格:¥电议型 号:T14706产 地:中国大陆

  • T14696BnO-PEG1-CH2CO2tBu;化合物 T14696BnO-PEG1-CH2CO2tBu

    BnO-PEG1-CH2CO2tBu is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14696产 地:中国大陆

  • T14690BMS 433796;化合物BMS 433796BMS-289948|||BMS-299897;BMS-289948|||BMS-299897

    BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer´s disease.

    价 格:¥电议型 号:T14690产 地:中国大陆

  • T14686BMS-986163;化合物 T14686BMS-986163

    BMS-986163 is a negative allosteric modulator of GluN2B and the prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).

    价 格:¥电议型 号:T14686产 地:中国大陆

  • T14656Bis-propargyl-PEG3;化合物 T14656Bis-propargyl-PEG3

    Bis-propargyl-PEG3 is a PEG-based PROTAC linker utilized for the synthesis of PROTACs. It is also employed in the synthesis of antiplasmodial zinc-dipicolylamine (ZnDPA) complexes[1] [2].

    价 格:¥电议型 号:T14656产 地:中国大陆

  • T14646Bis-PEG6-NHS ester;化合物 T14646Bis-PEG6-NHS ester

    Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

    价 格:¥电议型 号:T14646产 地:中国大陆

  • T14636Bis-PEG3-PFP ester;化合物 T14636Bis-PEG3-PFP ester

    Bis-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14636产 地:中国大陆

  • T14626Bis-PEG1-acid;化合物 T14626Bis-PEG1-acid

    Bis-PEG1-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14626产 地:中国大陆

  • T14606Biotin-PEG6-acid;化合物 T14606Biotin-PEG6-acid

    Biotin-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14606产 地:中国大陆

  • T14596Biotin-PEG3-propionic hydrazide;化合物 T14596Biotin-PEG3-propionic hydrazide

    Biotin-PEG3-propionic hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14596产 地:中国大陆

  • T14586Biotin-PEG2-Mal;化合物 T14586Biotin-PEG2-Mal

    Biotin-PEG2-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14586产 地:中国大陆

  • T14576Biotin-C5-NHS Ester;化合物 T14576Biotin-C5-NHS Ester

    Biotin-C5-NHS Ester is an alkyl/ether-based linker for PROTAC synthesis[1].

    价 格:¥电议型 号:T14576产 地:中国大陆

  • T14569BI8626;化合物 BI8626BI8626

    BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells.

    价 格:¥电议型 号:T14569产 地:中国大陆

  • T14566BI-9627;化合物 T14566BI-9627

    BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).

    价 格:¥电议型 号:T14566产 地:中国大陆

  • T14556BI-167107;化合物 T14556BI-167107

    BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).

    价 格:¥电议型 号:T14556产 地:中国大陆

  • T14536Benzyl-PEG2-Tos;化合物 T14536Benzyl-PEG2-Tos

    Benzyl-PEG2-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T14536产 地:中国大陆

  • T14521BDP9066;化合物 BDP9066BDP9066

    BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.

    价 格:¥电议型 号:T14521产 地:中国大陆

  • T14516BDP FL DBCO;化合物 T14516BDP FL DBCO

    BDP FL DBCO is a cleavable linker vital in ADC synthesis. BDP FL DBCO joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

    价 格:¥电议型 号:T14516产 地:中国大陆

  • T14206Ambutonium bromide;化合物 T14206BL700;BL700

    Ambutonium bromide is an antagonist of acetylcholine.

    价 格:¥电议型 号:T14206产 地:中国大陆

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