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T14716Boc-Aminooxy-PEG3-thiol;化合物 T14716Boc-Aminooxy-PEG3-thiol
Boc-Aminooxy-PEG3-thiol is a polyethylene glycol (PEG)-based PROTAC linker, employed for the synthesis of PROTACs[1].
价 格:¥电议型 号:T14716产 地:中国大陆
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T14706Boc-Aminooxy-PEG1-azide;化合物 T14706Boc-Aminooxy-PEG1-azide
Boc-Aminooxy-PEG1-azide is a polyethylene glycol (PEG) derived linker compound designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14706产 地:中国大陆
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T14696BnO-PEG1-CH2CO2tBu;化合物 T14696BnO-PEG1-CH2CO2tBu
BnO-PEG1-CH2CO2tBu is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14696产 地:中国大陆
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T14690BMS 433796;化合物BMS 433796BMS-289948|||BMS-299897;BMS-289948|||BMS-299897
BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer´s disease.
价 格:¥电议型 号:T14690产 地:中国大陆
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T14686BMS-986163;化合物 T14686BMS-986163
BMS-986163 is a negative allosteric modulator of GluN2B and the prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).
价 格:¥电议型 号:T14686产 地:中国大陆
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T14656Bis-propargyl-PEG3;化合物 T14656Bis-propargyl-PEG3
Bis-propargyl-PEG3 is a PEG-based PROTAC linker utilized for the synthesis of PROTACs. It is also employed in the synthesis of antiplasmodial zinc-dipicolylamine (ZnDPA) complexes[1] [2].
价 格:¥电议型 号:T14656产 地:中国大陆
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T14646Bis-PEG6-NHS ester;化合物 T14646Bis-PEG6-NHS ester
Bis-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14646产 地:中国大陆
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T14636Bis-PEG3-PFP ester;化合物 T14636Bis-PEG3-PFP ester
Bis-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14636产 地:中国大陆
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T14626Bis-PEG1-acid;化合物 T14626Bis-PEG1-acid
Bis-PEG1-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14626产 地:中国大陆
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T14606Biotin-PEG6-acid;化合物 T14606Biotin-PEG6-acid
Biotin-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14606产 地:中国大陆
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T14596Biotin-PEG3-propionic hydrazide;化合物 T14596Biotin-PEG3-propionic hydrazide
Biotin-PEG3-propionic hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14596产 地:中国大陆
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T14586Biotin-PEG2-Mal;化合物 T14586Biotin-PEG2-Mal
Biotin-PEG2-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14586产 地:中国大陆
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T14576Biotin-C5-NHS Ester;化合物 T14576Biotin-C5-NHS Ester
Biotin-C5-NHS Ester is an alkyl/ether-based linker for PROTAC synthesis[1].
价 格:¥电议型 号:T14576产 地:中国大陆
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T14569BI8626;化合物 BI8626BI8626
BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells.
价 格:¥电议型 号:T14569产 地:中国大陆
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T14566BI-9627;化合物 T14566BI-9627
BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).
价 格:¥电议型 号:T14566产 地:中国大陆
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T14556BI-167107;化合物 T14556BI-167107
BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR, Kd of 84 pM).
价 格:¥电议型 号:T14556产 地:中国大陆
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T14536Benzyl-PEG2-Tos;化合物 T14536Benzyl-PEG2-Tos
Benzyl-PEG2-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14536产 地:中国大陆
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T14521BDP9066;化合物 BDP9066BDP9066
BDP9066 is a potent and selective MRCK inhibitor, inhibits MRCKβ and MRCKα/β, and can be used for the prevention and treatment of skin cancer.
价 格:¥电议型 号:T14521产 地:中国大陆
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T14516BDP FL DBCO;化合物 T14516BDP FL DBCO
BDP FL DBCO is a cleavable linker vital in ADC synthesis. BDP FL DBCO joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T14516产 地:中国大陆
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T14206Ambutonium bromide;化合物 T14206BL700;BL700
Ambutonium bromide is an antagonist of acetylcholine.
价 格:¥电议型 号:T14206产 地:中国大陆