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T61710Antileishmanial agent-7;化合物 Antileishmanial agent-7Antileishmanial agent-7
Antileishmanial agent-7 (compound 23) exhibits strong antileishmanial activity against Leishmania donovani and L-6, with IC50 values of 6.89 and 259 μM, respectively [1].
价 格:¥电议型 号:T61710产 地:中国大陆
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T61560Antileishmanial agent-5;化合物 Antileishmanial agent-5Antileishmanial agent-5
Antileishmanial agent-4 is a ribonucleoside analogue with potent activity against L.infantum and T.cruzi, having EC 50 values of 0.68 μM and 0.83 μM, respectively [1].
价 格:¥电议型 号:T61560产 地:中国大陆
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T61416Antileishmanial agent-9;化合物 Antileishmanial agent-9Antileishmanial agent-9
Antileishmanial agent-9 (compound 16c) exhibits potent and selective activity against Leishmania donovani (L. donovani) with an IC50 value of 4.01 μM. In addition, this compound demonstrates relatively low cytotoxicity in L-6 cells, with an IC50 value of 40.1 μM [1].
价 格:¥电议型 号:T61416产 地:中国大陆
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T61391Antileishmanial agent-3;化合物 Antileishmanial agent-3Antileishmanial agent-3
Antileishmanial agent-3 (Compound 13) effectively inhibits the growth of Leishmania major [1].
价 格:¥电议型 号:T61391产 地:中国大陆
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T61100Antileishmanial agent-4;化合物 Antileishmanial agent-4Antileishmanial agent-4
Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].
价 格:¥电议型 号:T61100产 地:中国大陆
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T60638Antileishmanial agent-8;化合物 Antileishmanial agent-8Antileishmanial agent-8
Antileishmanial agent-8 (compound 18) shows potent and selective activity against Leishmania donovani ( L. donovani ) (IC50 = 5.64 μM) with relatively low cytotoxicity in L-6 cells (IC 50 =73.9 μM) [1].
价 格:¥电议型 号:T60638产 地:中国大陆
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T57145-O-Demethylnobiletin;去甲基川陈皮素5-DEMETHYLNOBILETIN;5-DEMETHYLNOBILETIN|||去甲基川陈皮素
5-O-Demethylnobiletin (5-DEMETHYLNOBILETIN) is a natual product, has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-2.
价 格:¥电议型 号:T5714产 地:中国大陆
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T4795Pimelic acid;庚二酸Pileric acid|||1,7-Heptanedioic acid|||1,5-Pentanedicarboxylic acid;Pileric acid|||1
Derivatives of Pimelic acid (1,5-Pentanedicarboxylic acid) can participate in the biosynthesis of lysine.
价 格:¥电议型 号:T4795产 地:中国大陆
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T40933Bromochloroacetonitrile;溴代氯乙腈Bromochloroacetonitrile
Bromochloroacetonitrile is a chemical compound that is formed as a by-product during the chlorine disinfection process of water that contains natural organic material. This compound exhibits direct mutagenic activity and can induce DNA strand breakage.
价 格:¥电议型 号:T40933产 地:中国大陆
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T40868Tribromoacetonitrile;TribromoacetonitrileTribromoacetonitrile
Tribromoacetonitrile is a nitrogen-containing disinfection byproduct.
价 格:¥电议型 号:T40868产 地:中国大陆
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T40691Bromodichloroacetonitrile;溴二氯乙腈Bromodichloroacetonitrile
Bromodichloroacetonitrile is a nitrogen-containing disinfection byproduct.
价 格:¥电议型 号:T40691产 地:中国大陆
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T40117Antileishmanial agent-1;Antileishmanial agent-1Antileishmanial agent-1
Antileishmanial agent-1 demonstrates activity against both L. amazonensis promastigotes (IC 50 = 15.52 μM) and intracellular amastigotes (IC 50 = 4.10 μM).
价 格:¥电议型 号:T40117产 地:中国大陆
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T39679Lenalidomide-I;Lenalidomide-ILenalidomide-I
Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, such as the PROTAC BET degrader QCA570, by linking it to the targeted protein ligand through a linker.
价 格:¥电议型 号:T39679产 地:中国大陆
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T39672Ac-Ile-Glu-Thr-Asp-pNA;Ac-Ile-Glu-Thr-Asp-pNAAc-Ile-Glu-Thr-Asp-pNA
Ac-Ile-Glu-Thr-Asp-pNA is a caspase-8 substrate that undergoes enzymatic binding and cleavage specifically at the Ile-Glu-Thr-Asp (IETD) peptide sequence. This cleavage results in the release of p-nitroalinide, which can be quantitatively measured using colorimetric detection at 405 nm. This measure serves as an indicator of caspase-8 enzyme activity.
价 格:¥电议型 号:T39672产 地:中国大陆
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T38795Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride;Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochlorideSuc-Ile-Glu
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a chromogenic substrate specifically designed for factor Xa.
价 格:¥电议型 号:T38795产 地:中国大陆
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T38777Ilexoside O;冬青苷OIlexoside O
Ilexoside O, a triterpene saponin derived from Ilex pubescens roots, demonstrates modest inhibition of xanthine oxidase (XOD) activity with an IC50 value of 53.05 μM.
价 格:¥电议型 号:T38777产 地:中国大陆
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T383722-Fluoro-4-iodo benzonitrile;2-Fluoro-4-iodo benzonitrile2-Fluoro-4-iodo benzonitrile
2-Fluoro-4-iodo benzonitrile is a building block.1,2It has been used in the synthesis ofL. infantumtrypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.12-Fluoro-4-iodo benzonitrile has also been used in the synthesis of transient receptor potential ankyrin 1 (TRPA1) antagonists.2
价 格:¥电议型 号:T38372产 地:中国大陆
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T37504Cathepsin D and E FRET Substrate;Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH?Cathepsin
Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.
价 格:¥电议型 号:T37504产 地:中国大陆
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T37072Nitroxynil;硝碘酚腈4-Hydroxy-3-iodo-5-nitrobenzonitrile|||Trodax|||Dovenix;4-Hydroxy-3-iodo-5-nitrobenzo
Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) is an anthelmintic compound that effectively targets parasites in both adult and immature stages. It is extensively employed in investigations pertaining to Fasciola hepatica infection.
价 格:¥电议型 号:T37072产 地:中国大陆
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T36623Antileukinate;AntileukinateAntileukinate
Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury.
价 格:¥电议型 号:T36623产 地:中国大陆