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T82342Gamma-Glutamyl Transferase-IN-2;化合物 Gamma-Glutamyl Transferase-IN-2Gamma-Glutamyl Transferase-IN-2
Gamma-Glutamyl Transferase-IN-2 (compound 4dq), a β-carboline 1-hydrazide inhibitor, exhibits both antifungal and antibacterial properties by targeting glutamyltransferase. Its mode of action includes inducing reactive oxygen species accumulation, compromising cell membranes, and disrupting histone acetylation processes [1].
价 格:¥电议型 号:T82342产 地:中国大陆
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T82226HDAC6-IN-21;化合物 HDAC6-IN-21HDAC6-IN-21
HDAC6-IN-21 (compound 13) is an irreversible inhibitor of histone deacetylase 6 (HDAC6) [1].
价 格:¥电议型 号:T82226产 地:中国大陆
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T82225HDAC6-IN-24;化合物 HDAC6-IN-24HDAC6-IN-24
HDAC6-IN-24 (compound N1) is an inhibitor of histone deacetylase 6 (HDAC6) [1].
价 格:¥电议型 号:T82225产 地:中国大陆
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T82224HDAC6-IN-25;化合物 HDAC6-IN-25HDAC6-IN-25
HDAC6-IN-25 (compound 8) is a potent and selective HDAC6 inhibitor, exhibiting an IC50 value of 0.6 nM [1].
价 格:¥电议型 号:T82224产 地:中国大陆
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T82189HMGB1-IN-2;化合物 HMGB1-IN-2HMGB1-IN-2
HMGB1-IN-2 (compound 15) is a selective inhibitor of the highly conserved nuclear protein HMGB1, demonstrating no inhibitory effect at an IC50 of 20.2 μM in RAW264.7 cells. At a concentration of 30 μM, HMGB1-IN-2 reduces IL-1β, TNF-α, and caspase-1 p20 levels, and inhibits NF-κB p65 phosphorylation, providing anti-apoptotic effects. In vivo, HMGB1-IN-2 at a dose of 15 mg/kg administered intraperitoneally alleviates kidney injury in a mouse model of septic acute kidney injury. Furthermore, it inh
价 格:¥电议型 号:T82189产 地:中国大陆
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T82167HSP70/SIRT2-IN-2;化合物 HSP70/SIRT2-IN-2HSP70/SIRT2-IN-2
HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].
价 格:¥电议型 号:T82167产 地:中国大陆
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T82166HSP90-IN-27;化合物 HSP90-IN-27HSP90-IN-27
HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1].
价 格:¥电议型 号:T82166产 地:中国大陆
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T82125ICMT-IN-2;化合物 ICMT-IN-2ICMT-IN-2
ICMT-IN-2 (compound 45) serves as an ICMT inhibitor with an IC50 value of 0.168 μM [1].
价 格:¥电议型 号:T82125产 地:中国大陆
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T82124ICMT-IN-20;化合物 ICMT-IN-20ICMT-IN-20
ICMT-IN-20 (compound 54) serves as an ICMT inhibitor with an IC50 value of 0.682 μM [1].
价 格:¥电议型 号:T82124产 地:中国大陆
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T82123ICMT-IN-21;化合物 ICMT-IN-21ICMT-IN-21
ICMT-IN-21 (compound 6ag) is an ICMT inhibitor with an IC50 value of 8.8 ?M, featuring sulfonamide-modified farnesyl cysteine (SMFC). Its farnesyl and carboxylic acid motifs are critical for ICMT inhibition [1].
价 格:¥电议型 号:T82123产 地:中国大陆
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T82122ICMT-IN-22;化合物 ICMT-IN-22ICMT-IN-22
ICMT-IN-22 (compound 62) acts as an ICMT inhibitor with an IC50 value of 0.63 μM [1].
价 格:¥电议型 号:T82122产 地:中国大陆
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T82121ICMT-IN-23;化合物 ICMT-IN-23ICMT-IN-23
ICMT-IN-23 (compound 36) serves as an inhibitor of ICMT, exhibiting a half-maximal inhibitory concentration (IC50) of 0.123 μM [1].
价 格:¥电议型 号:T82121产 地:中国大陆
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T82120ICMT-IN-24;化合物 ICMT-IN-24ICMT-IN-24
ICMT-IN-24 (compound 63) is an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting potent activity with an IC50 value of 0.19 μM [1].
价 格:¥电议型 号:T82120产 地:中国大陆
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T82119ICMT-IN-25;化合物 ICMT-IN-25ICMT-IN-25
ICMT-IN-25 (compound 37) serves as a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.025 μM [1].
价 格:¥电议型 号:T82119产 地:中国大陆
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T82118ICMT-IN-26;化合物 ICMT-IN-26ICMT-IN-26
ICMT-IN-26 (compound 38) acts as an ICMT inhibitor with an IC50 value of 0.36 μM [1].
价 格:¥电议型 号:T82118产 地:中国大陆
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T82117ICMT-IN-27;化合物 ICMT-IN-27ICMT-IN-27
ICMT-IN-27, also known as compound 64, is an inhibitor of the enzyme ICMT, demonstrating potent activity with an IC50 value of 0.1 ?M [1].
价 格:¥电议型 号:T82117产 地:中国大陆
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T82116ICMT-IN-28;化合物 ICMT-IN-28ICMT-IN-28
ICMT-IN-28 (compound 65) serves as an inhibitor of ICMT, exhibiting significant potency with an IC50 value of 0.008 μM [1].
价 格:¥电议型 号:T82116产 地:中国大陆
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T82115ICMT-IN-29;化合物 ICMT-IN-29ICMT-IN-29
ICMT-IN-29, also known as compound 66, effectively inhibits ICMT with an IC50 value of 0.019 μM [1].
价 格:¥电议型 号:T82115产 地:中国大陆
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T82082IDO1-IN-23;化合物 IDO1-IN-23IDO1-IN-23
IDO1-IN-23 (compound 41) is a potent inhibitor of human indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 13 μM [1].
价 格:¥电议型 号:T82082产 地:中国大陆
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T82073Immune cell migration-IN-2;化合物 Immune cell migration-IN-2Immune cell migration-IN-2
Immune cell migration-IN-2 is a potent inhibitor of immune cell migration, exhibiting an EC50 value of 13.5 nM in a T-cell adhesion assay. This compound is utilized in research pertaining to dry-eye and other retinal diseases [1]. As a click chemistry reagent, Immune cell migration-IN-2 possesses an alkyne group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
价 格:¥电议型 号:T82073产 地:中国大陆