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T14405Azido-PEG1-C2-acid；化合物 T14405Azido-PEG1-C2-acid
Azido-PEG1-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14405产 地：中国大陆
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T14404Azido-PEG1-C1-Boc；化合物 T14404Azido-PEG1-C1-Boc
Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker utilized for PROTAC synthesis[1].
价 格：￥电议型 号：T14404产 地：中国大陆
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T14403Azido-PEG1-Boc；化合物 T14403Azido-PEG1-Boc
Azido-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14403产 地：中国大陆
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T14402Azido-PEG1-amine；化合物 T14402Azido-PEG1-amine
Azido-PEG1-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14402产 地：中国大陆
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T14401Azido-C2-SS-PEG2-C2-acid；化合物 T14401Azido-C2-SS-PEG2-C2-acid
Azido-C2-SS-PEG2-C2-acid is a two-unit cleavable PEG linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].
价 格：￥电议型 号：T14401产 地：中国大陆
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T14400Azide-PEG8-alcohol；化合物 T14400Azide-PEG8-alcohol
Azide-PEG8-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14400产 地：中国大陆
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T1440Ethacridine lactate monohydrate乳酸依沙吖啶一水物乳酸依沙吖啶一水物|||利凡诺
Ethacridine lactate hydrate is a topically applied anti-infective agent.
价 格：￥电议型 号：T1440产 地：中国大陆
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T14384AZD8797；化合物KAND567KAN-0440567|||KAND567；KAN-0440567|||KAND567
AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2, and potentially protects against SARS-CoV-2-induced neuronal damage, preventing worsening of nociceptive sensitization and microglial activation in a migraine model of rats following seizures.
价 格：￥电议型 号：T14384产 地：中国大陆
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T14362LAY 9944 dihydrochloride；化合物AY 9944 盐酸盐AY 9944 dihydrochloride
AY 9944 dihydrochloride is a intermediate.
价 格：￥电议型 号：T14362L产 地：中国大陆
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T14362AY 9944；化合物AY 9944AY 9944
AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol[1][2][3]. AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
价 格：￥电议型 号：T14362产 地：中国大陆
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T14344Atrimustine；阿莫司汀KM2210|||Bestrabucil；阿莫司汀|||KM2210|||Bestrabucil
Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate. It has the antitumor activity.
价 格：￥电议型 号：T14344产 地：中国大陆
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T14324Artemisone；青蒿酮BAY 44-9585|||Artemifone；BAY 44-9585|||Artemifone|||青蒿酮
Artemisone (BAY 44-9585) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains (IC50: 0.83 nM). It also is a potent inhibitor of human CMV.
价 格：￥电议型 号：T14324产 地：中国大陆
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T1430Betamipron；倍他米隆CS-443|||N-Benzoyl-β-alanine；CS-443|||N-Benzoyl-β-alanine|||倍他米隆
Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.
价 格：￥电议型 号：T1430产 地：中国大陆
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T14244Amino-PEG5-Boc；化合物 T14244Amino-PEG5-Boc
Amino-PEG5-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T14244产 地：中国大陆
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T14208AMD 3465；化合物 T14208GENZ-644494；GENZ-644494
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells.
价 格：￥电议型 号：T14208产 地：中国大陆
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T14144AGN-195183；化合物 T14144AGN-195183
AGN 195183 is a potent and selective agonist of RARα(Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. IC50 value: 3 nM (Kd); 200 nM (EC80, RAR Trans.) Target: RARα agonist Compound 4(AGN-195183) inhibited the growth of breast cancer cell lines, and was inactive in an in vivo model of topical irritation. Compound 4 (AGN 195183) is currently in Phase I/IIA clinical trials in cancer patients. Compound 4 and ATRA inhibit growth of the human breast cancer cell
价 格：￥电议型 号：T14144产 地：中国大陆
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T14072A-443654；化合物A-443654A-443654
A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).
价 格：￥电议型 号：T14072产 地：中国大陆
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T14067A-1165442；化合物 T14067A-1165442
A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.
价 格：￥电议型 号：T14067产 地：中国大陆
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T140444E2RCat；化合物4E2RCat4E2RCat
4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expression and the production of infectious virus.
价 格：￥电议型 号：T14044产 地：中国大陆
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T140051G244；化合物1G2441G244
1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties. 1G244 had the IC50 values of 14 and 53 nM against DPP8 and DPP9, and The Ki values for 1G244 were 0.9 and 4.2 nM for DPP8 and DPP9
价 格：￥电议型 号：T14005产 地：中国大陆
