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T6119BLZ945BLZ945
BLZ945 is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.
价 格：￥电议型 号：T6119产 地：美洲
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T6302LonafarnibLonafarnib,Sch66336,Sarasar
Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
价 格：￥电议型 号：T6302产 地：美洲
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T6390Anagrelide HClAnagrelide HCl,Anagrelide hydrochloride,BL4162A
Anagrelide Hydrochloride(BL4162A) is a drug used for the treatment of essential thrombocytosis.
价 格：￥电议型 号：T6390产 地：美洲
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T6518GossypolGossypol,BL 193,Pogosin
Gossypol Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
价 格：￥电议型 号：T6518产 地：美洲
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T6574LumiracoxibLumiracoxib,COX-189,Prexige
Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
价 格：￥电议型 号：T6574产 地：美洲
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T8845UTL-5g；化合物UTL-5g3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-|||GBL-5g；3-Isoxazolecarboxa
UTL-5g (3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity. It lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice, and acts as a novel chemo- and radioprotective agent.
价 格：￥电议型 号：T8845产 地：中国大陆
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T8782MitoBloCK-11u00A0(MB-11)；化合物MitoBloCK-11u00A0(MB-11)MitoBloCK-11u00A0(MB-11)
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
价 格：￥电议型 号：T8782产 地：中国大陆
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T8598CHEMBL241987；化合物CHEMBL2419872-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE；2-PHENYL-2,5-DIHYD
CHEMBL241987 targets the Adenosine receptor A3 (human)
价 格：￥电议型 号：T8598产 地：中国大陆
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T84384i；化合物4iCHEMBL1269981|||5-HT3 antagonist-4i；CHEMBL1269981|||5-HT3 antagonist-4i
4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.
价 格：￥电议型 号：T8438产 地：中国大陆
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T84321BLU-222；化合物 BLU-222BLU-222
BLU-222 is a potent, selective and orally active CDK2 inhibitor. BLU-222 shows robust antitumor activity.
价 格：￥电议型 号：T84321产 地：中国大陆
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T83857Soluble Epoxide Hydrolase PROTAC 1a；化合物 Soluble Epoxide Hydrolase PROTAC 1asEH Proteolysis-targeting
Soluble epoxide hydrolase (sEH) PROTAC 1a is a proteolysis-targeting chimera (PROTAC) comprising a cereblon ligand linked to the sEH inhibitor t-TUCB via a linker, promoting selective sEH degradation and inhibiting its hydrolase activity (IC50 = 0.8 nM) significantly more than its phosphatase activity (IC50 = >10,000 nM). This compound preferentially targets cytosolic sEH for lysosomal rather than proteasomal degradation. Furthermore, it mitigates thapsigargin-induced upregulation of phosphoryla
价 格：￥电议型 号：T83857产 地：中国大陆
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T83729Tat-CIRP TFA；化合物 Tat-CIRP TFATat-Cold-inducible RNA Binding Protein；Tat-Cold-inducible RNA Binding P
Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-2. This disrupts the MD-2 and CIRP interaction as confirmed in co-immunoprecipitation assays. Notably, in vivo studies reveal that Tat-CIRP, at dosages of 10 and 20 mg/kg, significantly reduces infarct volume in both a mouse model of middle cerebral artery occlusion (MCAO) and a
价 格：￥电议型 号：T83729产 地：中国大陆
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T83711Abl Substrate Peptide TFA；化合物 Abl Substrate Peptide TFAAbl Substrate Peptide TFA
Abl substrate peptide, a peptide substrate specifically phosphorylated by the tyrosine kinase Abl rather than c-Src kinase at 20 ?M, serves to quantify Abl kinase activity in vitro. This selective phosphorylation underscores its utility for measuring Abl´s enzymatic function.
价 格：￥电议型 号：T83711产 地：中国大陆
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T83705BING TFA；化合物 BING TFABlocker of Inter-membrane Stress Responses of Gram-negative Bacteria；Blocker of
BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gram-positive bacteria, notably including methicillin-resistant S. aureus (MRSA; MICs = 4-64 ?g/ml). Furthermore, BING enhances the effectiveness of antibiotics such as ampicillin, amoxicillin, and novobiocin against P. aeruginosa, and it prevents resistance development to kanamycin
价 格：￥电议型 号：T83705产 地：中国大陆
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T83703BLP-3 TFA；化合物 BLP-3 TFABombin-like Peptide 3；Bombin-like Peptide 3
BLP-3, an endogenous peptide derived from X. laevis skin, exhibits antibacterial efficacy against N. meningitidis, N. gonorrhoeae, N. lactamica, and N. cinerea at a concentration of 20 ?g/ml. Characterized by its ability to fold into an alpha-helix, BLP-3 penetrates and disrupts bacteriomimetic membranes, underlying its mechanism of action.
价 格：￥电议型 号：T83703产 地：中国大陆
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T8322BL-918；化合物BL-918BL-918
BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.
价 格：￥电议型 号：T8322产 地：中国大陆
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T82909BCR-ABL-IN-8；化合物 BCR-ABL-IN-8BCR-ABL-IN-8
BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].
价 格：￥电议型 号：T82909产 地：中国大陆
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T82859Blepharotriol；化合物 BlepharotriolBlepharotriol
Blepharotriol, a phenolic triterpene isolated from Maytenus blepharodes, exhibits antimicrobial activity, with a minimum inhibitory concentration (MIC) of 8-4 ?g/ml against Bacillus subtilis. It also demonstrates cytotoxic activity, with half-maximal inhibitory concentrations (IC50s) of 12.2 ?M for HeLa cells, and greater than 20 ?M for both Hep-2 and Vero cells [1].
价 格：￥电议型 号：T82859产 地：中国大陆
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T82858Bleselumab；化合物 BleselumabASKP 1240|||Anti-Human CD40 Recombinant Antibody；ASKP 1240|||Anti-Human CD4
Bleselumab (ASKP 1240), a human anti-CD40 monoclonal antibody (mAb), exhibits high-affinity binding to CD40 (Kd: 0.24 nM) and hinders immune responses by impeding the CD40-CD40L interaction, thereby preventing organ transplant rejection [1].
价 格：￥电议型 号：T82858产 地：中国大陆
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T82857Blestriarene B；化合物 Blestriarene B(-)-Blestriarene B；(-)-Blestriarene B
(-)-Blestriarene B, a stilbenoid derived from the tubers of Bletilla striata (Orchidaceae), was isolated based on its ability to inhibit tubulin polymerization [1].
价 格：￥电议型 号：T82857产 地：中国大陆
