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产品数:86101
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TN4661NodosinI. Japonicus,Isodon trichocarpus,inhibit,Nodosin,Inhibitor,diterpenoid
Nodosin has an anti-inflammatory function via inhibition of IL-2. Nodosin perfusion provides a potential protective effect by inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transplantation.
价 格:¥电议型 号:TN4661产 地:中国大陆
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T6756AMG 925CDK,AMG 925,Cluster of differentiation antigen 135,FLT3,Cyclin dependent kinase,inhibit,CD135
AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.
价 格:¥电议型 号:T6756产 地:中国大陆
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T9516BinodenosonMRE 0470,imaging,P1 receptor,stress,oxidative,WRC0470,neutrophil,inhibit,radiotracers,Bin
Binodenoson is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1].
价 格:¥电议型 号:T9516产 地:中国大陆
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T7714TemocapilMn-SOD,inhibit,Temocaprilat,Cu/ZnSOD,renal diseases,heart failure,hypertension,Temocapril,i
Temocapril is an inhibitor of tyrosine kinase.
价 格:¥电议型 号:T7714产 地:中国大陆
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T7912(?)-MyrtenalAkt,hyperglycemia,terpene,inhibit,GLUT2,Protein kinase B,Inhibitor,diabetic,(?) Myrtenal
(1R)-( )-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
价 格:¥电议型 号:T7912产 地:中国大陆
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TP1422Interleukin (IL)-6 ReceptorInterleukin (IL) 6 Receptor,Interleukin (IL)6 Receptor
Interleukin (IL)-6 Receptor is a peptide.
价 格:¥电议型 号:TP1422产 地:中国大陆
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T6702TerbinafineFungal,bacteria,Candida,Inhibitor,squalene epoxidase,Terbinafine,Bacterial,Antibiotic,TDT
Terbinafine is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.
价 格:¥电议型 号:T6702产 地:中国大陆
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T9054RO6889678inhibit,Hepatitis B virus,coregulated protein,UDP-glucuronosyltransferase,HB capsid formati
RO6889678 is HBV inhibitor with a complex ADME profile.
价 格:¥电议型 号:T9054产 地:中国大陆
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TN1990NorathyriolNatural,Antioxidant,Peroxisome proliferator-activated receptors,anti-bacterial,inhibit,an
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
价 格:¥电议型 号:TN1990产 地:中国大陆
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T6S1141Ganoderic acid AInhibitor,Autophagy,Ganoderic acid A,Apoptosis,inhibit,Endogenous Metabolite
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly su
价 格:¥电议型 号:T6S1141产 地:中国大陆
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T6654SaponinsSaponins,Inhibitor,Fungal,inhibit,Bacterial
Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effective for the treatment/prevention of venous insufficiency.
价 格:¥电议型 号:T6654产 地:中国大陆
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T7007UNC2025Inhibitor,inhibit,FLT3,leukemia,CD135,Fms like tyrosine kinase 3,acute,Cluster of differentia
UNC-2025( IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
价 格:¥电议型 号:T7007产 地:中国大陆
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TQ0059Ilorasertibanti-tumor,H1299,Platelet-derived growth factor receptor,Inhibitor,ABT 348,antiproliferat
Ilorasertib (ABT-348) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora A/Aurora B/Aurora C (IC50s: 120 nM/7 nM/1 nM). It also suppresses RET tyrosine kinase, PDGFRβ, and Flt1 (IC50s: 7 nM, 3 nM, and 32 nM).
价 格:¥电议型 号:TQ0059产 地:中国大陆
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TN3849Dihydrodehydrodiconiferyl alcoholDihydrodehydrodiconiferyl alcohol
Dihydrodehydrodiconiferyl alcohol is the methanolic extract of Liriodendron tulipifera[1].
价 格:¥电议型 号:TN3849产 地:中国大陆
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T6437CefoperazoneCefoperazone,inhibit,Inhibitor,Antibiotic,Bacterial
Cefoperazone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. It can inhibit rMrp2-mediated [3H]E217βG uptake (IC50: 199 μM).
价 格:¥电议型 号:T6437产 地:中国大陆
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T8973HS-1793HIF-1α,Inhibitor,MCF-7,HS 1793,breast cancer,inhibit,ERK,HCT116,resveratrol,VEGF,Apoptosis,HS
HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model
价 格:¥电议型 号:T8973产 地:中国大陆
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T8580Bupranololnon-selective,competitive,Adrenergic Receptor,Bupranolol,Inhibitor,intrinsic,sympathomimet
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
价 格:¥电议型 号:T8580产 地:中国大陆
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T76922,4-DPDCollagen formation,Diethyl ester,Chick-embryo calvaria,2,4DPD,inhibit,Inhibitor,Prolyl hydrox
2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)
价 格:¥电议型 号:T7692产 地:中国大陆
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TN1589Dihydrowithaferin ADihydrowithaferin A,2,3-Dihydrowithaferin A,inhibit,Inhibitor,Cholinesterase (ChE
Dihydrowithaferin A is a withanolide isolated from Withania somnifera with activity against acetylcholinesterase (AChE). Dihydrowithaferin A in the diet may prevent or decrease the growth of tumors.
价 格:¥电议型 号:TN1589产 地:中国大陆
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T8867RO2959 HydrochlorideIP3,SOCE,Ca2+ release-activated Ca2+ channels,RO2959 Hydrochloride,Interleukin R
RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.
价 格:¥电议型 号:T8867产 地:中国大陆