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TP2312MOTS-c(Human) Acetate(1627580-64-6 free)MOTSc(Human) Acetate(1627580646 free),MOTS c(Human) Acetate(
MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity.
价 格:¥电议型 号:TP2312产 地:中国大陆
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T8849PF-9601Nexcitotoxicity,neurodegenerative diseases,MAO,PF9601N,Monoamine Oxidase,MAO-B inhibitor,neur
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
价 格:¥电议型 号:T8849产 地:中国大陆
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T9030SU4984inhibit,growth,Fibroblast growth factor receptor,Insulin Receptor,fibroblast,insulin,SU4984,SU
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
价 格:¥电议型 号:T9030产 地:中国大陆
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T8139Sulfamethoxazole sodiumAntibiotic,infection,Sulfamethoxazole sodium,Trimethoprim,pathogen,Inhibitor,
Sulfamethoxazole sodium is a sulfonamide bacteriostatic antibiotic
价 格:¥电议型 号:T8139产 地:中国大陆
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Fr12564Compound Fr12564Compound Fr12564
价 格:¥电议型 号:Fr12564产 地:中国大陆
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T10960Darbufelone
Darbufelone is a non-competitive dual inhibitor of PGF2α and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGHS-2 and PGHS-1.
价 格:¥电议型 号:T10960产 地:中国大陆
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T8202Kaempferol 3-O-gentiobiosideKaempferol 3Ogentiobioside,inhibit,Kaempferol 3 O gentiobioside,Inhibito
Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).
价 格:¥电议型 号:T8202产 地:中国大陆
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T11013L1Dextrorotation nimorazole phosphate ester TFADextrorotationnimorazolephosphateesterTFA
Dextrorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.
价 格:¥电议型 号:T11013L1产 地:中国大陆
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TN1576Diallyl disulfidecholesterol biosynthesis,squalene monooxygenase,Inhibitor,inhibit,Diallyl disulfide
Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22.
价 格:¥电议型 号:TN1576产 地:中国大陆
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T28036MI-2-2cell proliferation,inhibit,menin-MLL interaction,Epigenetic Reader Domain,Inhibitor,Hoxa9 expr
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
价 格:¥电议型 号:T28036产 地:中国大陆
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T7093RafoxanideHemonchus,Rafoxanide,energy metabolism,inhibit,antiparasitic,Parasite,Fasciola,Estrus ovis
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
价 格:¥电议型 号:T7093产 地:中国大陆
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T8606n-acetylciprofloxacinnacetylciprofloxacin,n acetylciprofloxacin
n-acetylciprofloxacin is inhibitor of H37Rv.
价 格:¥电议型 号:T8606产 地:中国大陆
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T1782LCanagliflozin hemihydrate
Canagliflozin hemihydrate is a drug of the gliflozin class or subtype 2 sodium-glucose transport inhibitors used for the treatment of type 2 diabetes. SGLT2 is responsible for at least 90% of renal glucose reabsorption (SGLT1 being responsible for the remaining 10%). Blocking this transporter causes up to 119 grams of blood glucose per day to be eliminated through the urine, corresponding to 476 kilocalories.
价 格:¥电议型 号:T1782L产 地:中国大陆
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T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE
Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.
价 格:¥电议型 号:T7846产 地:中国大陆
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TN2260Taxifolin 7-O-rhamnosideInhibitor,Taxifolin 7Orhamnoside,Taxifolin 7 O rhamnoside,inhibit
Taxifolin 7-O-rhamnoside is a natural product from Hypericum japonicum.
价 格:¥电议型 号:TN2260产 地:中国大陆
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T6S1572Sauchinoneantioxidant,LPS,Diastereomeric,TNF-α,iNOS,anti-inflammatory,lignan,COX-2,inhibit,Nuclear f
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative stress in vivo and in vitro. 3. Sauchinone diminishes LPS-induced neutrophil activation and acute lung injury. 4. Sauchinone-induced HO-1 expression plays a key role in the vascular protective effects of Sauchinone in HUVEC. 5. Sauchinone protects skin keratinocytes through inhi
价 格:¥电议型 号:T6S1572产 地:中国大陆
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T8478SC-43antiproliferative,Inhibitor,SC-43,SHP-1,PTPN6,Phosphatase,Apoptosis,caspase-3,SC 43,anti-fibrot
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
价 格:¥电议型 号:T8478产 地:中国大陆
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T9584UNC6934Inhibitor,UNC6934,Histone Methyltransferase,inhibit,UNC 6934,UNC-6934
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
价 格:¥电议型 号:T9584产 地:中国大陆
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T6778BDA-366Inhibitor,BDA-366,Antitumor,Bcl-2 Family,inhibit,Bcl2-BH4 domain,Anticancer,BDA 366,Antiapopt
BDA-366 is a potent Bcl2 antagonist, binding Bcl2-BH4 domain with high affinity and selectivity (Ki = 3.3 nM). BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells[1].
价 格:¥电议型 号:T6778产 地:中国大陆