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T73974Olmesartan ethyl ester；化合物 Olmesartan ethyl esterOlmesartan ethyl ester
Olmesartan ethyl ester (compound 11), an impurity of Olmesartan (RNH-6270), functions as an antagonist to the angiotensin II receptor (AT1R), primarily utilized in studies related to high blood pressure [1].
价 格：￥电议型 号：T73974产 地：中国大陆
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T7391SAR407899；化合物SAR407899SAR407899
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
价 格：￥电议型 号：T7391产 地：中国大陆
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T72867Fusarisetin A；化合物 Fusarisetin AFusarisetin A
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor [1] .
价 格：￥电议型 号：T72867产 地：中国大陆
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T72732Massarilactone H；化合物 Massarilactone HMassarilactone H
Massarilactone H, a polyketide, is a neuraminidase inhibitor, with an IC 50 of 8.18 ?M [1] .
价 格：￥电议型 号：T72732产 地：中国大陆
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T72718SARS-CoV-2-IN-36；化合物 SARS-CoV-2-IN-36SARS-CoV-2-IN-36
SARS-CoV-2-IN-36 is a potent inhibitor of SARS-CoV-2 Mpro (SARS-CoV), demonstrating an IC50 of 2.37 μM and a Kd of 1.19 μM in enzymatic assays. This compound exhibits antiviral activity against SARS-CoV-2 variants UC-1074, RG2674, and NVDBB-2220 in Vero cells.
价 格：￥电议型 号：T72718产 地：中国大陆
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T72671SARS-CoV-2-IN-12；化合物 SARS-CoV-2-IN-12SARS-CoV-2-IN-12
SARS-CoV-2-IN-12, a potent inhibitor of the SARS-CoV-2-related 3C-like protease (K_i=32.1 pM), plays a crucial role in preventing SARS-CoV-2 viral replication, showcasing potential significance in COVID-19 research.
价 格：￥电议型 号：T72671产 地：中国大陆
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T72581SARS-CoV MPro-IN-2；化合物 SARS-CoV MPro-IN-2SARS-CoV MPro-IN-2
SARS-CoV MPro-IN-2 effectively inhibits the SARS-CoV-2 main protease (M pro), crucial for the virus´s replication and transcription in host cells, with an IC50 value of 72.07 nM. Given its significant role in processing viral polyproteins, M pro is regarded as a key target in drug discovery efforts. Consequently, SARS-CoV MPro-IN-2 holds promise for COVID-19 research.
价 格：￥电议型 号：T72581产 地：中国大陆
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T72451SARS-CoV-2 Mpro-IN-6；化合物 SARS-CoV-2 Mpro-IN-6SARS-CoV-2 Mpro-IN-6
SARS-CoV-2 Mpro-IN-6 is a selective, covalent, and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), exhibiting an inhibition concentration (IC50) of 0.18 μM. It does not inhibit human cathepsins B, F, K, and L or caspase 3.
价 格：￥电议型 号：T72451产 地：中国大陆
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T72447SARS-CoV-2 Mpro-IN-5；化合物 SARS-CoV-2 Mpro-IN-5SARS-CoV-2 Mpro-IN-5
SARS-CoV-2 Mpro-IN-5 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL) with IC50 values of 1800 nM and 145 nM, respectively. This compound demonstrates antiviral activity by inhibiting SARS-CoV-2 replication in hACE2 expressing A549 cells, with an IC50 value of 14.7 nM.
价 格：￥电议型 号：T72447产 地：中国大陆
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T72446SARS-CoV-2 Mpro-IN-4；化合物 SARS-CoV-2 Mpro-IN-4SARS-CoV-2 Mpro-IN-4
SARS-CoV-2 Mpro-IN-4 is a dual inhibitor targeting Main Protease (M Pro) and Cathepsin L (CatL), exhibiting inhibition concentrations (IC50) of 900 nM and 60 nM, respectively. It demonstrates antiviral activity by effectively blocking SARS-CoV2 replication in hACE2-expressing A549 cells with an IC50 value of 8.2 nM.
价 格：￥电议型 号：T72446产 地：中国大陆
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T72371SARS-CoV-2 3CLpro-IN-7；化合物 SARS-CoV-2 3CLpro-IN-7SARS-CoV-2 3CLpro-IN-7
SARS-CoV-2 3CLpro-IN-7 is a reversible covalent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an inhibitory concentration (IC50) value of 1.4 ?M.
价 格：￥电议型 号：T72371产 地：中国大陆
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T72370SARS-CoV-2 3CLpro-IN-6；化合物 SARS-CoV-2 3CLpro-IN-6SARS-CoV-2 3CLpro-IN-6
SARS-CoV-2 3CLpro-IN-6 is a reversible covalent inhibitor targeting the SARS-CoV-2 3CL protease, demonstrating potent inhibitory activity with an IC50 of 4.9 μM. It is utilized in the research of coronavirus disease 2019 (COVID-19).
价 格：￥电议型 号：T72370产 地：中国大陆
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T72364SARS-CoV-2 3CLpro-IN-5；化合物 SARS-CoV-2 3CLpro-IN-5SARS-CoV-2 3CLpro-IN-5
SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), exhibiting potent inhibitory activity with an IC50 of 3.8 nM and demonstrating 9.0% oral bioavailability (BA). It is utilized in the research of coronavirus disease 2019 (COVID-19) [1].
价 格：￥电议型 号：T72364产 地：中国大陆
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T72313SARS-CoV-2 3CLpro-IN-11；化合物 SARS-CoV-2 3CLpro-IN-11SARS-CoV-2 3CLpro-IN-11
SARS-CoV-2 3CLpro-IN-11(11d) is a broad-spectrum antiviral compound that effectively inhibits the SARS-CoV-2 3CL protease, achieving an IC50 of 140 nM. Additionally, it exhibits inhibitory activity against SARS-CoV-1 and MERS-CoV with IC50 values of 240 nM and 70 nM, respectively.
价 格：￥电议型 号：T72313产 地：中国大陆
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T72312SARS-CoV-2 3CLpro-IN-10；化合物 SARS-CoV-2 3CLpro-IN-10SARS-CoV-2 3CLpro-IN-10
SARS-CoV-2 3CLpro-IN-10(5d) is a potent inhibitor of the SARS-CoV-2 3CL protease, exhibiting an IC50 value of 190 nM, and demonstrates varied efficiency against other coronaviruses with IC50 values of 790 nM for SARS-CoV-1 and 70 nM for MERS-CoV, indicating broad-spectrum antiviral activity.
价 格：￥电议型 号：T72312产 地：中国大陆
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T72231SARS-CoV-2/MERS Mpro-IN-2；化合物 SARS-CoV-2/MERS Mpro-IN-2SARS-CoV-2/MERS Mpro-IN-2
SARS-CoV-2/MERS Mpro-IN-2 is a potent inhibitor of the main proteases of SARS-CoV-2 and MERS, demonstrating IC50 values of 0.21 and 0.07 ?M, respectively.
价 格：￥电议型 号：T72231产 地：中国大陆
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T72230SARS-CoV-2/MERS Mpro-IN-1；化合物 SARS-CoV-2/MERS Mpro-IN-1SARS-CoV-2/MERS Mpro-IN-1
SARS-CoV-2/MERS Mpro-IN-1 is a potent inhibitor of the main proteases in SARS-CoV-2 and MERS, exhibiting IC50 values of 0.10 and 0.06 ?M, respectively.
价 格：￥电议型 号：T72230产 地：中国大陆
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T71608Fimasartan potassium trihydrate；化合物 Fimasartan potassium trihydrateFimasartan potassium trihydrate
Fimasartan potassium trihydrate is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure.
价 格：￥电议型 号：T71608产 地：中国大陆
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T7134Mavacamten；化合物MYK-461MYK-461|||SAR439152；MYK-461|||SAR439152
Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
价 格：￥电议型 号：T7134产 地：中国大陆
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T71112SAR156497；化合物 SAR156497SAR156497
SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A); 1 nM (Aurora B / incenp); 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP 3A4 and PDE3 inhibition. In vitro, SAR156497 displayed high antiproliferative activity on a large panel of tumor cell lines without correlation with any particular genetic signature or Aurora kinases expressi
价 格：￥电议型 号：T71112产 地：中国大陆
