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T11891Lumefantrine-d18;苯芴醇 D18Benflumetol D18|||Lumefantrine D18;Benflumetol D18|||苯芴醇 D18|||Lumefantrine
Lumefantrine D18 is an antimalarial drug, and is the deuterium labeled Lumefantrine.
价 格:¥电议型 号:T11891产 地:中国大陆
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T1186LIfenprodil;艾芬地尔RC 61-91|||RC-61-91|||RC61-91|||RC 6191;RC 61-91|||RC-61-91|||RC61-91|||艾芬地尔|||RC 619
Ifenprodil (RC61-91) is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, Ifenprodil inhibits GIRK channels and interacts with alpha1 adrenergic, serotonin, and sigma receptors.
价 格:¥电议型 号:T1186L产 地:中国大陆
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T11818LAS191954;化合物 T11818LAS191954
LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM).
价 格:¥电议型 号:T11818产 地:中国大陆
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T11810L791943;化合物 T11810L791943
L791943 is a selective, potent) inhibitor of Phosphodiesterase-4 (PDE4,IC50 of 4.2 nM).
价 格:¥电议型 号:T11810产 地:中国大陆
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T11791KW-6055;化合物 T11791KW-6055
KW-6055 has anti-amnesic activity, is a benzylpyridine derivative.
价 格:¥电议型 号:T11791产 地:中国大陆
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T11691IV-23;化合物 T11691IV-23
IV-23, a potent inhibitor of cell growth both in vitro and in vivo, effectively reduces colony formation, arrests the cell cycle at the M phase, and induces apoptosis in esophageal squamous cell carcinoma through Noxa-mediated pathways. This compound emerges as a promising anticancer agent with significant potential.
价 格:¥电议型 号:T11691产 地:中国大陆
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T11591Hydroxyzine D4羟嗪 D4羟嗪 D4
Hydroxyzine D4 is a deuterium-labeled variation of Hydroxyzine, a chemical compound known for its anticholinergic, anxiolytic, and analgesic properties. It is classified as a heterocyclic histamine H1-receptor antagonist.
价 格:¥电议型 号:T11591产 地:中国大陆
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T11491GSK2973980A;化合物 T11491GSK2973980A
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
价 格:¥电议型 号:T11491产 地:中国大陆
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T11487LFiboflapon sodium;化合物 T11487LGSK2190915 sodium salt|||AM-803 sodium;GSK2190915 sodium salt|||AM-803
Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
价 格:¥电议型 号:T11487L产 地:中国大陆
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T11487Fiboflapon;化合物FiboflaponGSK2190915|||AM-803;GSK2190915|||AM-803
Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM.
价 格:¥电议型 号:T11487产 地:中国大陆
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T11463GR 103691;化合物GR 103691GR 103691
GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM). It shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites.
价 格:¥电议型 号:T11463产 地:中国大陆
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T11391LGepotidacin;化合物 T11391LGSK2140944;GSK2140944
Gepotidacin is a novel triazaacenaphthylene inhibitor of bacterial type II topoisomerase.
价 格:¥电议型 号:T11391L产 地:中国大陆
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T11391Gepotidacin S enantiomer;化合物 T11391GSK2140944 S enantiomer;GSK2140944 S enantiomer
Gepotidacin S enantiomer is an S enantionmer of gepotidacin.
价 格:¥电议型 号:T11391产 地:中国大陆
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T11291FKBP12 PROTAC dTAG-13;化合物 T11291dTAG-13;dTAG-13
FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN. FKBP12 PROTAC dTAG-13 (dTAG-13) is a PROTAC-based heterobifunctional degrader.
价 格:¥电议型 号:T11291产 地:中国大陆
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T11277FG 7142;化合物FG 7142ZK 39106|||LSU-65;ZK 39106|||LSU-65
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).
价 格:¥电议型 号:T11277产 地:中国大陆
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T11246Etoricoxib-d4;依托考昔 D4MK-0663 D4|||L-791456 D4|||Etoricoxib D4;MK-0663 D4|||依托考昔 D4|||L-791456 D4|||E
Etoricoxib D4 is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.Etoricoxib D4 is a deuterium labeled Etoricoxib.
价 格:¥电议型 号:T11246产 地:中国大陆
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T11191EN6;化合物EN6EN6
EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activation of autophagy. EN6 clears TDP-43 aggregates, a causative agent in frontotemporal dementia, in a lysosome-dependent manner. EN6 is a small-molecule in vivo activator of autophagy that covalently targets cysteine 277 in the ATP6V1A subunit of the lysosomal the vacuolar H+ ATPase (v-ATPase).
价 格:¥电议型 号:T11191产 地:中国大陆
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T11147EC5026;化合物EC5026BPN-19186;BPN-19186
EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.
价 格:¥电议型 号:T11147产 地:中国大陆
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T11033DI-591;化合物 T11033DI-591
DI-591 is an effective, high-affinity and cell-permeability inhibitor for DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 and nM and 10.4 nM, respectively, and has no obvious binding to DCN3, DCN4 and DCN5 proteins.
价 格:¥电议型 号:T11033产 地:中国大陆
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T10991Dehydronitrosonisoldipine;化合物DehydronitrosonisoldipineDehydronitrosonisoldipine
Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.
价 格:¥电议型 号:T10991产 地:中国大陆