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T10589BPN-15606 besylate (1914989-49-3 free base);化合物 T10589BPN-15606 besylate;BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格:¥电议型 号:T10589产 地:中国大陆
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T10566BMS-191095;化合物BMS-191095BMS-191095
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
价 格:¥电议型 号:T10566产 地:中国大陆
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T10552Bitopertin (R enantiomer);化合物 T10552RO4917838 (R enantiomer)|||RG1678 (R enantiomer)|||Bitopertin R
Bitopertin R enantiomer (RG1678 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a noncompetitive glycine reuptake inhibitor and inhibits glycine uptake at human GlyT1 (IC50: 25 nM).
价 格:¥电议型 号:T10552产 地:中国大陆
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T10493Beclabuvir;贝拉布韦BMS-791325;BMS-791325
Beclabuvir (BMS-791325) is a potent NS5A replication complex inhibitor that inhibits the activity of the NS5B protein expressed by HCV genotypes 1, 2, 4, and 5 and is used in the study of HCV infection.
价 格:¥电议型 号:T10493产 地:中国大陆
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T10491LGalidesivir hydrochloride;化合物 T10491LBCX 4430 hydrochloride|||Immucillin-A hydrochloride;BCX 4430 hy
Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.
价 格:¥电议型 号:T10491L产 地:中国大陆
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T10491Galidesivir;加利司韦BCX4430|||Immucillin-A;BCX4430|||Immucillin-A
Galidesivir (BCX4430) is a broad-spectrum antiviral compound, an adenosine analog that inhibits viral RNA-dependent RNA polymerase (RdRp) activity.Galidesivir inhibits a wide range of RNA viral pathogens in vitro, and reduces lung infections in infected animals.
价 格:¥电议型 号:T10491产 地:中国大陆
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T10481LBAY 73-6691;化合物 T10481L(R)-BAY 73-6691;(R)-BAY 73-6691
BAY 73-6691 is an inhibitor of brain penetrant PDE9A.
价 格:¥电议型 号:T10481L产 地:中国大陆
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T10481BAY 73-6691 racemate;化合物 T10481BAY 73-6691 racemate
BAY 73-6691 racemate is a phosphodiesterase 9 inhibitor.
价 格:¥电议型 号:T10481产 地:中国大陆
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T10434AZD-5991;化合物 T10434AZD-5991
AZD-5991 is a potent and selective Mcl-1 inhibitor (IC50: 0.7 nM in FRET assay; Kd: 0.17 nM in SPR assay).
价 格:¥电议型 号:T10434产 地:中国大陆
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T10433Osimertinib dimesylate奥希替尼二甲磺酸盐奥希替尼二甲磺酸盐|||Mereletinib (dimesylate)|||AZD-9291 (dimesylate)
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).
价 格:¥电议型 号:T10433产 地:中国大陆
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T10391Aspirin Aluminum阿司匹林铝Aluminum diacetylsalicylate|||阿司匹林铝
Aspirin Aluminum is an intermolecular compound that can inhibit gastrointestinal mucosal disorders induced by NSAIDs.
价 格:¥电议型 号:T10391产 地:中国大陆
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T10370ARN 077化合物 T10370URB913
ARN 077 is a selective N-acylethanolamine acid amidase (NAAA) inhibitor (IC50: 7 nM for human NAAA). ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS.
价 格:¥电议型 号:T10370产 地:中国大陆
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T10366LArg-Gly-Asp-Ser acetate;化合物Arg-Gly-Asp-Ser acetateArg-Gly-Asp-Ser acetate(91037-65-9 free base);Arg-
Arg-Gly-Asp-Ser acetate is an integrin binding sequence that directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. Arg-Gly-Asp-Ser acetate inhibits integrin receptor function.
价 格:¥电议型 号:T10366L产 地:中国大陆
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T10319LAnamorelin Fumarate;富马酸阿拉莫林ONO-7643 Fumarate|||RC1291 Fumarate;ONO-7643 Fumarate|||RC1291 Fumarate||
Anamorelin Fumarate is a novel ghrelin receptor agonist (EC50: 0.74 nM in the FLIPR assay).
价 格:¥电议型 号:T10319L产 地:中国大陆
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T10291α-Truxillic acid;化合物 T10291α-Truxillic acid
α-Truxillic acid, known for its anti-inflammatory activities, is produced through the dimerization of two molecules of α-trans-cinnamic acid.
价 格:¥电议型 号:T10291产 地:中国大陆
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T10204A-317491 sodium salt hydrate;化合物 T10204A-317491 sodium salt hydrate (475205-49-3 free base);A-317491
A-317491 sodium salt hydrate is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors.
价 格:¥电议型 号:T10204产 地:中国大陆
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T10191L7-Chlorokynurenic acid;7-氯犬尿酸7-chloro-4-hydroxy-2-carboxyquinoline|||7-CKA;7-chloro-4-hydroxy-2-carb
7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.
价 格:¥电议型 号:T10191L产 地:中国大陆
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T101917-Chlorokynurenic acid sodium salt化合物 T101917-CKA sodium salt
7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the NMDA receptor (IC50: 0.56 μM). It is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles (Ki: 0.59 μM).
价 格:¥电议型 号:T10191产 地:中国大陆
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T101193-O-Methyltolcapone;化合物 T10119Ro 40-7591;Ro 40-7591
3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for treatment of Parkinson´s disease.
价 格:¥电议型 号:T10119产 地:中国大陆
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T101183-O-Methyltolcapone D7;化合物 T10118Ro 40-7591 D7;Ro 40-7591 D7
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone crosses the blood-brain barrier and can be used for treatment of Parkinson´s disease.
价 格:¥电议型 号:T10118产 地:中国大陆