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T11972Mcl-1 inhibitor 3;化合物 T11972Mcl-1 inhibitor 3
Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM; IC50=19 nM in an OPM-2 cell viability assay).
价 格:¥电议型 号:T11972产 地:中国大陆
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T11971MCL-1/BCL-2-IN-4;化合物 T11971MCL-1/BCL-2-IN-4
MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.
价 格:¥电议型 号:T11971产 地:中国大陆
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T11970MCL-1/BCL-2-IN-3;化合物 T11970MCL-1/BCL-2-IN-3
MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.
价 格:¥电议型 号:T11970产 地:中国大陆
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T1197Trimebutine maleate;马来酸曲美布汀Debridat|||Polibutin;Debridat|||Polibutin|||马来酸曲美布汀
Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors served as a spasmolytic drug for therapy of both chronic and acute abdominal pain.
价 格:¥电议型 号:T1197产 地:中国大陆
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T11897Telotristat ethyl;化合物Telotristat ethylLX1606;LX1606
Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
价 格:¥电议型 号:T11897产 地:中国大陆
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T11845LGD-6972;化合物LGD-6972LGD-6972
LGD-6972 is an antagonist of glucagon receptor.
价 格:¥电议型 号:T11845产 地:中国大陆
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T11819Lascufloxacin;拉库沙星KRP-AM1977X;拉库沙星|||KRP-AM1977X
Lascufloxacin, a potent and orally active fluoroquinolone antibacterial agent, holds potential for the treatment of various infectious diseases, including lower respiratory tract infections. It effectively inhibits infections caused by a wide range of pathogens, encompassing those resistant to quinolones.
价 格:¥电议型 号:T11819产 地:中国大陆
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T118066CDK9 inhibitor HH1;化合物CDK9 inhibitor HH18019-9719;8019-9719
CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.
价 格:¥电议型 号:T118066产 地:中国大陆
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T11723LJNJ-39758979;化合物JNJ-39758979JNJ-39758979
JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively). JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells.
价 格:¥电议型 号:T11723L产 地:中国大陆
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T116970TLC3407-3786;化合物 TLC3407-3786TLC3407-3786
MMV665916 is a quinazolinedione derivative that is an antimalarial agent. MMV665916 shows remarkable antiplasmodial activity against P. falciparum FcB1 strain with EC 50 value of 0.4 μM and presents the high selectivity index (SI>250) [1].
价 格:¥电议型 号:T116970产 地:中国大陆
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T11697IX 207-887;化合物 T11697IX 207-887
IX 207-887 inhibits the release of interleukin-1 (IL-1). IX 207-887 is a novel antiarthritic agent.
价 格:¥电议型 号:T11697产 地:中国大陆
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T11597LIACS-9571 Hydrochloride (1800477-30-8 free base);化合物 T11597LIACS-9571 Hydrochloride|||ASIS-P040 Hydr
IACS-9571 Hydrochloride is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
价 格:¥电议型 号:T11597L产 地:中国大陆
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T11597IACS-9571;化合物 T11597ASIS-P040;ASIS-P040
IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
价 格:¥电议型 号:T11597产 地:中国大陆
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T1156Palonosetron hydrochloride;盐酸帕洛诺司琼RS 25259 197|||Palonosetron HCl|||RS 25259;盐酸帕洛诺司琼|||RS 25259 197|
Palonosetron hydrochloride (RS 25259) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
价 格:¥电议型 号:T1156产 地:中国大陆
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T1152Albendazole;阿苯达唑SKF-62979;SKF-62979|||阿苯达唑
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
价 格:¥电议型 号:T1152产 地:中国大陆
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T11500LGSK3368715 dihydrochlorideGSK3368715盐酸盐EPZ019997 dihydrochloride|||GSK3368715 2HCl|||EPZ019997 2HCl
GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs) with anticancer and antitumor activity, inhibiting PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, and can be used to study advanced solid tumors.
价 格:¥电议型 号:T11500L产 地:中国大陆
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T11500GSK3368715;化合物 T11500EPZ019997;EPZ019997
GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50s: 3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). It has strong anti-cancer activity.
价 格:¥电议型 号:T11500产 地:中国大陆
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T11497Ganfeborole HCl;Ganfeborole 盐酸盐GSK3036656 HCl|||GSK656 HCl;GSK3036656 HCl|||GSK656 HCl
Ganfeborole HCl (GSK3036656 HCl) is a small molecule compound with anti-tuberculosis activity and is an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS; IC50: 0.2 μM).
价 格:¥电议型 号:T11497产 地:中国大陆
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T11491GSK2973980A;化合物 T11491GSK2973980A
GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).
价 格:¥电议型 号:T11491产 地:中国大陆
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T11408Orforglipron;奥格列隆LY3502970|||GLP-1 receptor agonist 1;LY3502970|||GLP-1 receptor agonist 1
Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.
价 格:¥电议型 号:T11408产 地:中国大陆