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T11397GGTI298；化合物 T11397GGTI298
GGTI298, a CAAZ peptidomimetic and potent geranylgeranyltransferase I (GGTase I) inhibitor, efficiently blocks the processing of geranylgeranylated Rap1A while exerting minimal impact on the processing of farnesylated Ha-Ras. The inhibitor displays in vivo IC50 values of 3 μM for Rap1A and >20 μM for Ha-Ras, respectively.
价 格：￥电议型 号：T11397产 地：中国大陆
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T11297LFF-10101；化合物FF-10101FF-10101
FF-10101 is a potent inhibitor of FLT3.
价 格：￥电议型 号：T11297L产 地：中国大陆
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T11297FF-10101 succinate；化合物 T11297FF-10101 succinate
FF-10101 succinate is a potent FLT3 inhibitor.
价 格：￥电议型 号：T11297产 地：中国大陆
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T11296Flosulide；化合物 T11296ZK 38997|||CGP 28238；ZK 38997|||CGP 28238
Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.
价 格：￥电议型 号：T11296产 地：中国大陆
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T11197Enclomiphene D4 hydrochloride；化合物 T11197(E)-Clomiphene D4 hydrochloride|||Enclomifene D4 hydrochlori
Enclomiphene D4 hydrochloride ((E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property.Enclomiphene D4 hydrochloride ((E)-Clomiphene D4 hydrochloride; trans-Clomiphene D4 hydrochloride; Enclomifene D4 hydrochloride) is a deuterium labeled Enclomiphene.
价 格：￥电议型 号：T11197产 地：中国大陆
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T11097Drobuline hydrochloride；盐酸羟布林Drobuline hydrochloride
Drobuline hydrochloride is an anti-arrhythmic agent with cardiac depressant activity.
价 格：￥电议型 号：T11097产 地：中国大陆
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T10997Derazantinib Racemate；化合物 T10997ARQ-087 Racemate；ARQ-087 Racemate
Derazantinib Racemate (ARQ-087 Racemate) is the racemate of Derazantinib. Derazantinib is an orally bioavailable, ATP competitive tyrosine kinase inhibitor. It exhibits potent activity against FGFR1/FGFR2/FGFR3 chondrocytes (IC50s: 4.5 nM/1.8 nM/4.5 nM).
价 格：￥电议型 号：T10997产 地：中国大陆
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T10979DCPIB；化合物DCPIBDCPIB
DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1/TRAAK channels.
价 格：￥电议型 号：T10979产 地：中国大陆
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T10978DCG-IV；化合物 T10978DCG-IV
DCG-IV is an effective agonist of class II mGluR. DCG-IV has anticonvulsant and neuroprotective effects. The EC50 of mGlu2R and mGlu3R are 0.35 and 0.09 μM, respectively. DCG-IV is also a competitive antagonist of Group I (IC50: mGlu1 / 5R = 389/630 μM) and III receptor (IC50: mGlu4 / 6/7 / 8R = 22.5 / 39.6 / 40.1 / 32 μM).
价 格：￥电议型 号：T10978产 地：中国大陆
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T10977DCEBIO；化合物DCEBIODCEBIO
DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84 colon cells.
价 格：￥电议型 号：T10977产 地：中国大陆
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T10976DC4SMe；化合物 T10976DC4SMe
The IC50s of DC4SMe on Ramos, Namalwa and HL60 / s cancer cells were 1.9 nM, 2.9 nM and 1.8 nM, respectively. DC4SMe can be used for targeted therapy of tumors. DC4SMe is a phosphate prodrug of the cytotoxic DNA alkylating agent DC4 and can be used in the synthesis of antibody-drug conjugates (ADC).
价 格：￥电议型 号：T10976产 地：中国大陆
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T10975DC44SMe；化合物 T10975DC44SMe
The IC50 of DC44SMe for Ramos, Namalwa and HL60 / s cancer cells was 2.0 nM, 2.8 nM and 1.9 nM, respectively. DC44SMe can be used for targeted treatment of cancer. DC44SMe is a phosphate prodrug of DC44 and can be used in the synthesis of antibody-drug conjugates (ADC).
价 格：￥电议型 号：T10975产 地：中国大陆
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T10974DC41；化合物 T10974DC41
DC41 is a derivative of DC1. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylating agents, used for targeted treatment of cancer.
价 格：￥电议型 号：T10974产 地：中国大陆
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T10973DC41SMe；化合物 T10973DC41SMe
DC41SMe is a DC1 derivative that is cytotoxic to Ramos, Namalwa and HL60 / s with IC50s ranging from 18-25 pM. DC1 is a simplified analogue of CC-1065, an antibody conjugate of cytotoxic DNA alkylation molecules, used for targeted treatment of cancer.
价 格：￥电议型 号：T10973产 地：中国大陆
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T10972DC4；化合物 T10972DC4
DC4 can be used to synthesize antibody-drug conjugate (ADC), which is an ADC cytotoxin. DC4 can be used for targeted therapy of tumors.
价 格：￥电议型 号：T10972产 地：中国大陆
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T10971DC10SMe；化合物 T10971DC10SMe
DC10SMe is a DNA alkylating agent that can be used in the synthesis of antibody-drug conjugates (ADC). The IC50 of DC10SMe for Ramos, Namalwa and HL60 / s cancer cells were 15 pM, 12 pM and 12 pM, respectively.
价 格：￥电议型 号：T10971产 地：中国大陆
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T10970DC1；化合物 T10970DC1
DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer, is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065.
价 格：￥电议型 号：T10970产 地：中国大陆
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T1097Loratadine；氯雷他定SCH 29851|||Loratidine；氯雷他定|||SCH 29851|||Loratidine
Loratadine (SCH 29851) is a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
价 格：￥电议型 号：T1097产 地：中国大陆
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T10964LDB1976 dihydrochloride；DB1976盐酸盐DB1976 hydrochloride|||DB1976 2HCl；DB1976 hydrochloride|||DB1976 2HC
DB1976 dihydrochloride (DB1976 2HCl) , a transcription factor PU.1 inhibitor with potential anti-inflammatory activity, slowed down inflammation and fibrosis and improved glucose homeostasis and dyslipidemia in mice in in vivo experiments.DB1976 dihydrochloride promotes apoptosis and may be used in studies of metabolic dysfunction and non-alcoholic steatohepatitis.
价 格：￥电议型 号：T10964L产 地：中国大陆
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T10964DB1976；化合物DB1976DB1976
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 has Apoptosis-inducing effect.
价 格：￥电议型 号：T10964产 地：中国大陆
