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T8818TC-G 1005化合物TC-G 1005(4-环丙基-3,4-二氢-1(2H)-喹喔啉基)[4-(2,5-二甲基苯氧基)-3-吡啶基]甲酮
TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.
价 格:¥电议型 号:T8818产 地:中国大陆
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T8681HA-1004 dihydrochloride;HA 1004 盐酸盐HA-1004 dihydrochloride
HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein
价 格:¥电议型 号:T8681产 地:中国大陆
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T8470BMS-1001;化合物BMS-1001BMS-1001
BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
价 格:¥电议型 号:T8470产 地:中国大陆
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T8443LMCI-225 hydrochloride hydrate;化合物 T8443LAA-10021|||AA10021|||MCI225|||DDP-225|||AA-10025|||AA-10026;
MCI-225 is a norepinephrine reuptake/5-HT3/5-HT reuptake inhibitor. MCI-225 could be effective in the treatment of senile dementia of the Alzheimer type, which is accompanied with both deficit in the BF-cortex cholinergic neuron and cerebral glucose hypometabolism. MCI-225 enhances attentional eye tracking in midpontine pretrigeminal preparation.
价 格:¥电议型 号:T8443L产 地:中国大陆
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T8439Clobenpropit dihydrobromide;丙酸倍氯松二溴酸盐溶液,1000PPMClobenpropit dihydrobromide
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
价 格:¥电议型 号:T8439产 地:中国大陆
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T83978Safingol hydrochloride;沙芬戈盐酸盐SPC 100270 hydrochloride|||L-threo-dihydrosphingosine hydrochloride;SPC
Safingol hydrochloride (L-threo-dihydrosphingosine hydrochloride) is a specific inhibitor of protein kinase C. It induces autophagy in solid tumor cells and cancer cell death by inhibiting the PKC and PI3-kinase pathways.BIIB 722 Mesylate is a selective sodium-hydrogen exchange inhibitor. Safingol hydrochloride inhibits PKC and PI3k.
价 格:¥电议型 号:T83978产 地:中国大陆
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T83945XIE62-1004;化合物 XIE62-1004XIE62-1004
XIE62-1004 is a chemical compound that induces the interaction between p62 and LC3 by binding to the ZZ domain of p62. This interaction promotes p62 self-aggregation and its subsequent interaction with LC3 on autophagosome membranes, thereby facilitating the delivery of cargo proteins to the autophagosome for degradation. XIE62-1004 is effective both in vitro and in vivo, displaying specificity for the wild type of p62 and exhibiting its actions in a concentration- and time-dependent manner. Add
价 格:¥电议型 号:T83945产 地:中国大陆
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T83942IDR 1002;化合物 IDR 1002IDR 1002
IDR 1002, an innate defense regulator peptide, effectively diminishes bacterial load and mitigates inflammatory responses in murine models of sinusitis and acute bacterial lung infections. It suppresses LPS-induced activation of NF-κB and COX-2 while promoting the phosphorylation and activation of p38, ERK1/2, MSK1, and CREB.
价 格:¥电议型 号:T83942产 地:中国大陆
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T83766Moexiprilat;化合物 MoexiprilatRS 10029;RS 10029
Moexiprilat, an active metabolite of the prodrug moexipril formed through side chain ester hydrolysis in vivo, functions as an angiotensin-converting enzyme (ACE; IC50 = 2.1 nM) inhibitor. At a concentration of 10 nM, it inhibits the proliferation of primary neonatal rat cardiac fibroblasts stimulated by estrone or angiotensin II. Furthermore, when given at a daily dosage of 50 mg/kg, moexiprilat reduces mean arterial blood pressure and elevates levels of atrial natriuretic peptide, an indicator
价 格:¥电议型 号:T83766产 地:中国大陆
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T83530LB-100;化合物 LB-100LB-100
(Rac)-LB-100 is the racemic form of the compound LB-100, which functions as an inhibitor of protein phosphatase 2A (PP2A) [1].
价 格:¥电议型 号:T83530产 地:中国大陆
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T83100Antibacterial agent 161 trifluoromethanesulfonate;化合物 Antibacterial agent 161 trifluoromethanesulfon
Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against colon cancer and non-small cell lung cancer [1].
价 格:¥电议型 号:T83100产 地:中国大陆
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T82917BAY-R 1005;化合物 BAY-R 1005BAY-R 1005
BAY-R 1005, a synthetic glycolipid analogue (GLA) with immunoenhancing properties, is designed to modulate antibody synthesis [1].
价 格:¥电议型 号:T82917产 地:中国大陆
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T82893Bevifimod;化合物 BevifimodPRTX-100;PRTX-100
Bevifimod (PRTX-100), a highly purified variant of Staphylococcal protein A (SpA), is utilized in research on idiopathic thrombocytopenic purpura (ITP) [1] [2].
价 格:¥电议型 号:T82893产 地:中国大陆
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T82874Biotin-PEG-Alk (MW 1000);化合物 Biotin-PEG-Alk (MW 1000)Biotin-PEG-Alk (MW 1000)
Biotin-PEG-Alk (MW 1000) is a biotinylated polyethylene glycol (PEG) derivative with alkyne functionality for click chemistry applications. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG provides hydrophilic, water-soluble, and low-toxicity characteristics. The alkyne group (Alk) facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with azido-modified molecules, enhancing the compound´s ability to target and bind with biotin receptors.
价 格:¥电议型 号:T82874产 地:中国大陆
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T82873Biotin-PEG-Alk (MW 10000);化合物 Biotin-PEG-Alk (MW 10000)Biotin-PEG-Alk (MW 10000)
Biotin-PEG-Alk (MW 10000) is a biotinylated polyethylene glycol (PEG) derivative featuring an alkyne group for click chemistry applications. This compound combines biotin, an enzyme co-factor used in protein labeling, with PEG, a hydrophilic, water-soluble, and low-toxicity polymer. The alkyne moiety facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azido-containing molecules, enhancing the efficiency of targeting biotin-binding entities.
价 格:¥电议型 号:T82873产 地:中国大陆
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T82663CU06-1004;化合物 CU06-1004Sac-1004;Sac-1004
CU06-1004 (Sac-1004) is an orally active compound that acts as an endothelial dysfunction blocker. It mitigates endothelial dysfunction by inhibiting hyperpermeability and inflammation. The compound demonstrates efficacy in reducing vascular leakage and inflammation across multiple animal models, including those for diabetic retinopathy, stroke, cancer, and inflammatory bowel disease. Additionally, CU06-1004 improves conditions in a CDAA-induced mouse model of NASH and enhances cardiac function
价 格:¥电议型 号:T82663产 地:中国大陆
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T82100ICMT-IN-42;化合物 ICMT-IN-42ICMT-IN-42
ICMT-IN-42 (compound 21) serves as an ICMT inhibitor, demonstrating potency with an IC50 of 0.054 μM [1].
价 格:¥电议型 号:T82100产 地:中国大陆
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T81100ST8155AA1;化合物 ST8155AA1ST8155AA1
ST8155AA1, a component of antibody-drug conjugates (ADCs), is tethered to an HDAC inhibitor via a linker and exhibits antitumor activity [1].
价 格:¥电议型 号:T81100产 地:中国大陆
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T81009Tetrahydroauroglaucin;化合物 TetrahydroauroglaucinTetrahydroauroglaucin
Tetrahydroauroglaucin, a hydroquinone derivative, exhibits antioxidative effects [1].
价 格:¥电议型 号:T81009产 地:中国大陆
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T81008Tetrahydropalmatrubine;化合物 TetrahydropalmatrubineTetrahydropalmatrubine
Tetrahydropalmatrubine, an alkaloid, is isolated from the herb Corydalis saxicola [1].
价 格:¥电议型 号:T81008产 地:中国大陆