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T1470Fexofenadine hydrochloride;盐酸非索非那定Terfenidine carboxylate hydrochloride|||MDL-16455 hydrochloride|||
Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria.
价 格:¥电议型 号:T1470产 地:中国大陆
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T14647Bis-PEG7-acid;化合物 T14647Bis-PEG7-acid
Bis-PEG7-acid and bis-PEG6-propionic acid are chemical compounds that serve as linkers in the synthesis of PROTACs and antibody-drug conjugates (ADCs), respectively. Bis-PEG7-acid is a PEG-based PROTAC linker, while bis-PEG6-propionic acid is a cleavable ADC linker[1].
价 格:¥电议型 号:T14647产 地:中国大陆
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T14547JWG-071;化合物JWG-071JWG071|||JWG 071;JWG071|||JWG 071
JWG-071, the first reported chemical probe for ERK5 kinase selectivity, is a BET-selective inhibitor with a 1 μM BRD4 IC that enhances both ERK5 activity and BRD4 selectivity.
价 格:¥电议型 号:T14547产 地:中国大陆
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T14495Baloxavir巴洛沙韦Baloxavir acid|||S-033447
Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit.
价 格:¥电议型 号:T14495产 地:中国大陆
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T14487AZM475271;化合物 T14487M475271;M475271
AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)
价 格:¥电议型 号:T14487产 地:中国大陆
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T14479Azido-PEG8-NHS ester;化合物 T14479Azido-PEG8-NHS ester
Azido-PEG8-NHS ester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl/ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].
价 格:¥电议型 号:T14479产 地:中国大陆
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T14478Azido-PEG8-CH2COO-PFP;化合物 T14478Azido-PEG8-CH2COO-PFP
Azido-PEG8-CH2COO-PFP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14478产 地:中国大陆
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T14477Azido-PEG8-C1-NHS ester;化合物 T14477Azido-PEG8-C1-NHS ester
Azido-PEG8-C1-NHS ester is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14477产 地:中国大陆
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T14476Azido-PEG8-Boc;化合物 T14476Azido-PEG8-Boc
Azido-PEG8-Boc is a polyethylene glycol (PEG) and alkyl/ether-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T14476产 地:中国大陆
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T14475Azido-PEG7-amine;化合物 T14475Azido-PEG7-amine
Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14475产 地:中国大陆
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T14474Azido-PEG8-amine;化合物 T14474Azido-PEG8-amine
Azido-PEG8-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14474产 地:中国大陆
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T14473Azido-PEG8-acid;化合物 T14473Azido-PEG8-acid
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14473产 地:中国大陆
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T14472Azido-PEG7-alcohol;化合物 T14472Azido-PEG7-alcohol
Azido-PEG7-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14472产 地:中国大陆
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T14471Azido-PEG6-PFP ester;化合物 T14471Azido-PEG6-PFP ester
Azido-PEG6-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14471产 地:中国大陆
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T14470Azido-PEG6-NHS ester;化合物 T14470Azido-PEG6-NHS ester
Azido-PEG6-NHS ester is a cleavable 6 unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG- and alkyl/ether based linker for the synthesis of proteolysis targeting chimeras (PROTACs)[2].
价 格:¥电议型 号:T14470产 地:中国大陆
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T1447Fenclonine芬克洛宁Fenchlonine|||PCPA|||CP-10188|||芬克洛宁|||4-Chloro-DL-phenylalanine|||DL-4-Chlorophenylal
Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine(CP-10188) acts pharmacologically to deplete endogenous levels of serotonin.
价 格:¥电议型 号:T1447产 地:中国大陆
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T14447Azido-PEG4-(CH2)3OH;化合物 T14447Azido-PEG4-(CH2)3OH
Azido-PEG4-(CH2)3OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14447产 地:中国大陆
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T1444Lomefloxacin洛美沙星洛美沙星|||SC47111A
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
价 格:¥电议型 号:T1444产 地:中国大陆
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T14347Aureothricin;金色抗霉素Aureothricin
Aureothricin, a dithiolopyrrolone (DTP) antibiotic originally derived from Streptomyces, demonstrates a broad-spectrum of antibacterial effectiveness. Additionally, it inhibits the adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin[1].
价 格:¥电议型 号:T14347产 地:中国大陆
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T14282Amuvatinib hydrochloride;化合物 T14282HPK 56 hydrochloride|||MP470 hydrochloride;HPK 56 hydrochloride||
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administred multi-targeted tyrosine kinase inhibitor that exhibits strong efficacy against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, while also acting as a suppressor of DNA repair by inhibiting the RAD51 protein, which is crucial for repairing DNA damage[1][2][3]. This dual mechanism contributes to its antineoplastic activity[4].
价 格:¥电议型 号:T14282产 地:中国大陆