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T14792Bromo-PEG2-CH2-Boc乙酸叔丁酯-二聚乙二醇-溴代乙酸叔丁酯-二聚乙二醇-溴代
Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
价 格:¥电议型 号:T14792产 地:中国大陆
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T14791Bromo-PEG2-C2-Boc;化合物 T14791Bromo-PEG2-C2-Boc
Bromo-PEG2-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14791产 地:中国大陆
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T14790Bromo-PEG2-C2-azide;化合物 T14790Bromo-PEG2-C2-azide
Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14790产 地:中国大陆
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T1479Isosorbide dinitrate;硝酸异山梨酯Isordil|||Nitrosorbide|||Sorbide nitrate|||Sorbidnitrate;硝酸异山梨酯|||Isordil
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.
价 格:¥电议型 号:T1479产 地:中国大陆
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T14789Bromo-PEG2-C2-acid;化合物 T14789Bromo-PEG2-C2-acid
Bromo-PEG2-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14789产 地:中国大陆
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T14788Bromo-PEG2-bromide;化合物 T14788Bromo-PEG2-bromide
Bromo-PEG2-bromide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14788产 地:中国大陆
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T14787Bromo-PEG2-alcohol;化合物 T14787Bromo-PEG2-alcohol
Bromo-PEG2-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14787产 地:中国大陆
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T14786Bromo-PEG1-CH2COOH;化合物 T14786Bromo-PEG1-CH2COOH
Bromo-PEG1-CH2COOH is a PROTAC linker can be used in the synthesis of PROTACs[1].
价 格:¥电议型 号:T14786产 地:中国大陆
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T14785Bromo-PEG1-CH2-Boc;化合物 T14785Bromo-PEG1-CH2-Boc
Bromo-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14785产 地:中国大陆
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T14784Bromo-PEG1-C2-Boc;化合物 T14784Bromo-PEG1-C2-Boc
Bromo-PEG1-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14784产 地:中国大陆
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T14783Bromo-PEG1-acid;化合物 T14783Bromo-PEG1-acid
Bromo-PEG1-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14783产 地:中国大陆
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T14782Brilaroxazine;化合物BrilaroxazineRP5063;RP5063
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-HT2B, and 5-HT7 receptors with Kis of 0.19 nM and 2.7 nM, respectively. Brilaroxazine can be used for research about cognitive impairments in neuropsychiatric and neurological diseases.
价 格:¥电议型 号:T14782产 地:中国大陆
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T14781Brilacidin;化合物 T14781PMX 30063;PMX 30063
Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics used for the research of eye infections.
价 格:¥电议型 号:T14781产 地:中国大陆
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T14780BRD9185;化合物 T14780BRD9185
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
价 格:¥电议型 号:T14780产 地:中国大陆
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T1478Ondansetron hydrochloride dihydrate;盐酸昂丹司琼SN 307|||NSC 665799|||GR 38032|||Ondansetron hydrochloride
Ondansetron hydrochloride dihydrate (GR 38032) is a competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
价 格:¥电议型 号:T1478产 地:中国大陆
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T14779BRD7389;化合物BRD7389BRD7389
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.
价 格:¥电议型 号:T14779产 地:中国大陆
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T14778BRD6989;化合物BRD6989BRD6989
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.
价 格:¥电议型 号:T14778产 地:中国大陆
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T14777BRD5529;化合物 T14777BRD5529
BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM). BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9.
价 格:¥电议型 号:T14777产 地:中国大陆
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T14776BRD4 Inhibitor-10;化合物BRD4 Inhibitor-10BRD4 Inhibitor-10
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
价 格:¥电议型 号:T14776产 地:中国大陆
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T14775Bragsin2;化合物Bragsin26-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one|||Bragsin 2;6-methoxy-5-nitro
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.
价 格:¥电议型 号:T14775产 地:中国大陆