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  • T16847SA 47;化合物 T16847SA 47

    SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.

    价 格:¥电议型 号:T16847产 地:中国大陆

  • T16817S-2474;化合物 S-2474S-2474

    S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced cell death.

    价 格:¥电议型 号:T16817产 地:中国大陆

  • T1677LMontelukast sodium孟鲁司特钠MK0476|||孟鲁司特钠

    Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.

    价 格:¥电议型 号:T1677L产 地:中国大陆

  • T16768Ro-24-4736;化合物 T16768Ro-24-4736

    Ro 24-4736 is an effective and selective platelet-activating factor antagonist.

    价 格:¥电议型 号:T16768产 地:中国大陆

  • T16763RN-1747;化合物RN-1747RN-1747

    RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: hTRPV4 of 0.77 μM, mTRPV4 of 4.0 μM, and rTRPV4 of 4.1 μM). RN-1747 also antagonizes TRPM8 (IC50: 4 μM).

    价 格:¥电议型 号:T16763产 地:中国大陆

  • T16747Riboflavin Tetrabutyrate;四丁酸核糖黄素酯Riboflavin Tetrabutyrate

    Riboflavin Tetrabutyrate is a lipophilic flavin derivative. Riboflavin Tetrabutyrate has antioxidative and lipid peroxide-removing activity.

    价 格:¥电议型 号:T16747产 地:中国大陆

  • T16702QL47;化合物QL47QL47

    QL47 is a host-targeted small molecule antiviral agent with antiviral activity against dengue and other RNA viruses.QL47 acts as an inhibitor of viral translation and a covalent inhibitor of BTK, and can be used in the study of lymphomas.

    价 格:¥电议型 号:T16702产 地:中国大陆

  • T16647Propargyl-PEG8-NHS ester;化合物 T16647Propargyl-PEG8-NHS ester

    Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

    价 格:¥电议型 号:T16647产 地:中国大陆

  • T1656LVandetanib Fumarate;化合物 T1656LHSDB 8198|||Zactima|||Caprelsa|||ZD 6474|||Vandetanib;HSDB 8198|||Zact

    Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a lesser extent VEGFR-1, which are important targets in thyroid cancer (TC).

    价 格:¥电议型 号:T1656L产 地:中国大陆

  • T1656Vandetanib凡德他尼ZD6474|||凡德他尼

    Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.

    价 格:¥电议型 号:T1656产 地:中国大陆

  • T16547PK14105;化合物 T16547PK14105

    PK14105 has been evaluated biologically as a potential radioligand for positron emission tomography (PET) studies targeting peripheral benzodiazepine binding sites (PBBS) receptors. When administered to rats with unilaterally lesioned striata, PK14105 was observed to quickly cross the blood-brain barrier, displaying significant radioactivity retention in the lesioned striatum, in contrast to the unlesioned striatum or cerebellar vermis. Additionally, PK14105 has the capability to inhibit recepto

    价 格:¥电议型 号:T16547产 地:中国大陆

  • T16515PF 750;化合物PF 750PF-750|||UNII-7756CPP14K|||ZINC27647189;PF-750|||UNII-7756CPP14K|||ZINC27647189

    PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.

    价 格:¥电议型 号:T16515产 地:中国大陆

  • T16505PF-4778574;化合物 T16505PF-4778574

    PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).

    价 格:¥电议型 号:T16505产 地:中国大陆

  • T16495PF-06747711;化合物 T16495PF-06747711

    PF-06747711 is an effective and selective retinoic acid receptor-related orphan C2 inverse agonist (IC50: 4.1 nM). PF-06747711 also has anti-skin inflammatory activity.

    价 格:¥电议型 号:T16495产 地:中国大陆

  • T16494PF-06471553化合物 T16494PF 06471553|||PF06471553

    PF-06471553 is an effective and selective inhibitor of monoacylglycerol acyltransferase 3 (IC50: 92 nM).

    价 格:¥电议型 号:T16494产 地:中国大陆

  • T16479PF-04937319;化合物PF-04937319PF-04937319

    PF-04937319 is an activator of glucokinase (EC50 =154.4 ?μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be used in research on the treatment of type 2 diabetes mellitus.

    价 格:¥电议型 号:T16479产 地:中国大陆

  • T16478PF-04447943化合物PF-04447943PF 04447943|||Edelinontrine|||PF04447943

    PF-04447943 (Edelinontrine) is a potent and selective phosphodiesterase 9A inhibitor with an IC50 of 12 nM, which is 78-fold more selective than that used for other PDE family members (IC50>1000 nM).PF-04447943 exhibits anti-inflammatory activity, attenuates inflammatory responses by inhibiting oxidative stress, inflammation, and modulating T-cell polarization, and may be useful for research on sickle cell anemia.

    价 格:¥电议型 号:T16478产 地:中国大陆

  • T16477PF-03715455;化合物 T16477PF-03715455

    PF-03715455 potently inhibits LPS-induced TNFα production in human whole blood (IC50=1.7 nM). PF-03715455 is an effective inhibitor of inhaled p38 MAPK. PF-03715455 displays some selectivity for p38α over p38β (respective IC50: 0.88 and 23 nM). PF-03715455 has the potential for the treatment of COPD.

    价 格:¥电议型 号:T16477产 地:中国大陆

  • T16476PF-03654746;化合物PF-03654746PF-03654746

    PF-03654746 is a selective antagonist of the histamine H3 receptor. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer´s disease. PF-03654746 can be used in studies about the treatment of allergic rhinitis.

    价 格:¥电议型 号:T16476产 地:中国大陆

  • T16475Pexacerfont化合物PexacerfontBMS-562086

    Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).

    价 格:¥电议型 号:T16475产 地:中国大陆

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