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T17901cIAP1 Ligand-Linker Conjugates 10;化合物 T17901E3 ligase Ligand-Linker Conjugates 47;E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROTAC linker. SNIPERs can be developed using cIAP1 Ligand-Linker Conjugates 10.
价 格:¥电议型 号:T17901产 地:中国大陆
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T1789Obeticholic Acid;奥贝胆酸INT-747|||6-Ethylchenodeoxycholic acid|||6-ECDCA;奥贝胆酸|||INT-747|||6-Ethylchenod
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist.
价 格:¥电议型 号:T1789产 地:中国大陆
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T17864DSPE-PEG47-acid;化合物 T17864DSPE-PEG47-acid
DSPE-PEG47-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17864产 地:中国大陆
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T17847DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000);化合物 T17847DSPE-PEG-2-Aminoethyl-alpha-mannopyr
DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker. This specific linker is utilized in the synthesis of PROTACs, or proteolysis targeting chimeras [1].
价 格:¥电议型 号:T17847产 地:中国大陆
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T17747DBCO-C3-PEG4-NH-Boc;化合物 T17747DBCO-C3-PEG4-NH-Boc
DBCO-C3-PEG4-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17747产 地:中国大陆
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T17647Boc-C1-PEG3-C4-OH;化合物 T17647Boc-C1-PEG3-C4-OH
Boc-C1-PEG3-C4-OH is an Alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs, which are characterized by their structure comprising two distinct ligands tethered by a linker. One ligand of PROTACs binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the targeted degradation of specific proteins[1].
价 格:¥电议型 号:T17647产 地:中国大陆
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T17547Biotin-C10-NHS Ester;化合物 T17547Biotin-C10-NHS Ester
Biotin-C10-NHS Ester is an alkyl/ether-based linker compound utilized in the synthesis of PROTACs[1].
价 格:¥电议型 号:T17547产 地:中国大陆
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T1754ZM 306416;化合物ZM 306416CB 676475;CB 676475
ZM 306416 (CB 676475), a VEGFR1 inhibitor (IC50: 0.33 μM), can also inhibit EGFR (IC50<10 nM).
价 格:¥电议型 号:T1754产 地:中国大陆
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T1747LTedizolid phosphate disodium salt;化合物 T1747LTorezolid phosphate sodium salt|||DA 7218|||TR-701|||TR
Tedizolid phosphate is a novel antibacterial prodrug. Tedizolid phosphate is a next-generation oxazolidinone with activity against both methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus spp. It also has effective activity against Gram-positive pathogens.
价 格:¥电议型 号:T1747L产 地:中国大陆
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T17479Azido-PEG10-Boc;化合物 T17479Azido-PEG10-Boc
Azido-PEG10-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17479产 地:中国大陆
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T17478Azido-PEG1-Val-Cit-OH;化合物 T17478Azido-PEG1-Val-Cit-OH
Azido-PEG1-Val-Cit-OH is a one-unit cleavable PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T17478产 地:中国大陆
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T17477Azido-PEG1-CH2COO-Cl;化合物 T17477Azido-PEG1-CH2COO-Cl
Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker, commonly employed in the synthesis of PROTAC BRD4 Degrader-1[1].
价 格:¥电议型 号:T17477产 地:中国大陆
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T17476Azido-PEG1-azide1,5-双叠氮-3-氧杂戊烷1,5-双叠氮-3-氧杂戊烷
Azido-PEG1-azide is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17476产 地:中国大陆
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T17475Azido-C3-UV-biotin;化合物 T17475UV Cleavable Biotin-PEG2-alkyne;UV Cleavable Biotin-PEG2-alkyne
Azido-C3-UV-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17475产 地:中国大陆
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T17474Azide-PEG9-amido-C8-Boc;化合物 T174749-(Azide-PEG9-ethylcarbamoyl)nonanoic t-butyl ester;9-(Azide-PEG9-
Azide-PEG9-amido-C8-Boc is a polyethylene glycol (PEG) derived linker compound utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17474产 地:中国大陆
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T17473Azide-PEG9-amido-C4-Boc;化合物 T174735-(Azide-PEG9-ethylcarbamoyl)pentanoic t-butyl ester;5-(Azide-PEG9
Azide-PEG9-amido-C4-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格:¥电议型 号:T17473产 地:中国大陆
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T17472Azide-PEG9-amido-C16-Boc;化合物 T1747217-(Azide-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester;17-(Azi
Azide-PEG9-amido-C16-Boc is an alkyl/ether-based PROTAC linker with utility in PROTAC synthesis [1].
价 格:¥电议型 号:T17472产 地:中国大陆
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T17471Azide-PEG9-amido-C12-Boc;化合物 T1747113-(Azide-PEG9-ethylcarbamoyl)tridecanoic t-butyl ester;13-(Azide
Azide-PEG9-amido-C12-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker used for the synthesis of PROTACs[1].
价 格:¥电议型 号:T17471产 地:中国大陆
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T17470Azide-PEG6-amido-C16-Boc;化合物 T1747017-(Azide-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester;17-(Azi
Azide-PEG6-amido-C16-Boc is an alkyl/ether-based PROTAC linker utilized in PROTAC synthesis[1].
价 格:¥电议型 号:T17470产 地:中国大陆
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T1747Tedizolid;特地唑胺TR 700|||DA-7157|||Torezolid;TR 700|||特地唑胺|||DA-7157|||泰地唑利|||Torezolid
Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome.
价 格:¥电议型 号:T1747产 地:中国大陆