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T1746LY-2584702 tosylate salt;化合物LY2584702 tosylateLY2584702 tosylate;LY2584702 tosylate
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.
价 格:¥电议型 号:T1746产 地:中国大陆
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T17447Aminoxyacetamide-PEG3-azide;化合物 T17447Aminoxyacetamide-PEG3-azide
Aminoxyacetamide-PEG3-azide is a non-cleavable 3-unit polyethylene glycol linker employed for antibody-drug conjugate (ADC) synthesis[1].
价 格:¥电议型 号:T17447产 地:中国大陆
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T1740BD-1047 dihydrobromide;化合物BD1047.2HBrBD1047.2HBr;BD1047.2HBr
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy in schizophrenia.
价 格:¥电议型 号:T1740产 地:中国大陆
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T1736Apixaban阿哌沙班阿哌沙班|||BMS-562247-01
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and preventing the formation of cross-linked fibrin clots.
价 格:¥电议型 号:T1736产 地:中国大陆
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T173447-O-(Cbz-N-amido-PEG4)-paclitaxel;化合物 T173447-O-(Cbz-N-amido-PEG4)-paclitaxel
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17344产 地:中国大陆
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T17303α-Cyclodextrin;α-环糊精Alfadex|||NSC269470|||NSC 269470|||NSC-269470;Alfadex|||NSC269470|||α-环糊精|||NSC
α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
价 格:¥电议型 号:T17303产 地:中国大陆
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T1730NPS-2143;化合物NPS 2143SB262470|||NPS 2143|||SB 262470A;SB262470|||NPS 2143|||SB 262470A|||2-氯-6-[(2R)-
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
价 格:¥电议型 号:T1730产 地:中国大陆
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T17257LWR99210 hydrochloride(47326-86-3 free base);化合物WR99210 hydrochlorideWR99210 hydrochloride(47326-86-3
WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
价 格:¥电议型 号:T17257L产 地:中国大陆
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T17247VU0661013;化合物VU0661013VU661013;VU661013
VU0661013 is an effective and selective inhibitor of MCL-1.
价 格:¥电议型 号:T17247产 地:中国大陆
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T17235Voclosporin;伏环孢素ISAtx-247;ISAtx-247
Voclosporin (ISAtx-247) is a novel and orally available calcium-modulated phosphatase (CN; PP2B) inhibitor and immunosuppressant for the treatment of lupus nephritis.
价 格:¥电议型 号:T17235产 地:中国大陆
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T17179Tulrampator化合物TulrampatorCX-1632|||S-47445
Tulrampator (S-47445) is an orally bioavailable positive AMPAR with antidepressant effects.
价 格:¥电议型 号:T17179产 地:中国大陆
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T17147TPOP146化合物 T17147TPOP 146|||TPOP-146|||TPOP146
TPOP146 is a selective CBP/P300 benzoxazepine bromodomain inhibitor (Kd: 134 nM and 5.02 μM for CBP and BRD4).
价 格:¥电议型 号:T17147产 地:中国大陆
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T17110TNP-470;化合物 T17110AGM-1470;AGM-1470
TNP-470 is a methionine aminopeptidase-2 inhibitor. TNP-470 is also an angiogenesis inhibitor.
价 格:¥电议型 号:T17110产 地:中国大陆
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T17096Tilapertin;化合物 T17096AMG747;AMG747
Tilapertin is an oral glycine transporter type-1 inhibitor.
价 格:¥电议型 号:T17096产 地:中国大陆
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T17047Tetrabenazine-d6丁苯那嗪 D6Ro 1-9569 D6|||丁苯那嗪 D6
Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.
价 格:¥电议型 号:T17047产 地:中国大陆
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T17031TEI-9647;化合物 T17031TEI-9647
TEI-9647 is a 1α,25-dihydroxy vitamin D3-26,23-lactone (1α,25-lactone) analog and is an effective VDR/vitamin D-responsive element (DRE)-mediated genomic actions antagonist.
价 格:¥电议型 号:T17031产 地:中国大陆
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T16947SU16f;化合物SU16f3-substituted indolin-2-one 16f|||SU-16F|||SU 16F;3-substituted indolin-2-one 16f|||SU
SU16f (3-substituted indolin-2-one 16f) is a potent and selective PDGFRβ inhibitor (IC50s: 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively). Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferation and migration.
价 格:¥电议型 号:T16947产 地:中国大陆
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T16926SR-31747;化合物 T16926SR-31747
SR-31747 blocks cell proliferation by inhibiting sterol isomerase. SR-31747 is a sigma ligand. It has immunosuppressive and anti-inflammatory properties.
价 格:¥电议型 号:T16926产 地:中国大陆
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T16906Sograzepide;化合物 T16906YM-220|||Netazepide|||YF 476;YM-220|||Netazepide|||YF 476
Sograzepide is an effective and highly selective Gastrin/CCK-B antagonist (IC50: 0.1 nM), has an inhibitory effect on Gastrin/CCK-A activity (IC50: 502 nM). Sograzepide replaces the specific binding of [125I]CCK-8 to the rat brain, cloned canine, and cloned human Gastrin/CCK-B receptors (Ki: 0.068, 0.62 and 0.19 nM, respectively).
价 格:¥电议型 号:T16906产 地:中国大陆
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T16862SCH-1473759;化合物 T16862SCH-1473759
SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).
价 格:¥电议型 号:T16862产 地:中国大陆