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T14464Azido-PEG5-succinimidyl carbonate;化合物 T14464Azido-PEG5-succinimidyl carbonate
Azido-PEG5-succinimidyl carbonate is a polyethylene glycol (PEG) derivative with a linked succinimidyl carbonate and azido group. It serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].
价 格:¥电议型 号:T14464产 地:中国大陆
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T14463Azido-PEG5-PFP ester;化合物 T14463Azido-PEG5-PFP ester
Azido-PEG5-PFP ester is a Polyethylene Glycol (PEG) and Alkyl/ether-based Proteolysis Targeting Chimera (PROTAC) linker, commonly employed for PROTAC synthesis [1].
价 格:¥电议型 号:T14463产 地:中国大陆
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T14462Azido-PEG5-NHS ester;化合物 T14462Azido-PEG5-NHS ester
Azido-PEG5-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14462产 地:中国大陆
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T14461Azido-PEG5-CH2CO2H;化合物 T14461Azido-PEG5-CH2CO2H
Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T14461产 地:中国大陆
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T14460Azido-PEG5-CH2CO2-PFP;化合物 T14460Azido-PEG5-CH2CO2-PFP
Azido-PEG5-CH2CO2-PFP is a polyethylene glycol (PEG) and Alkyl/ether-based linker compound. It serves as a key component in the synthesis of proteolysis-targeting chimeras (PROTACs), a class of molecules used for targeted protein degradation[1].
价 格:¥电议型 号:T14460产 地:中国大陆
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T1446Bambuterol hydrochloride;盐酸班布特罗(±)-Bambuterol hydrochloride|||KWD-2183 hydrochloride|||Bambuterol HC
Bambuterol hydrochloride (KWD-2183 hydrochloride) , a long-acting beta-adrenoceptor agonist, is utilized for the treating of asthma.
价 格:¥电议型 号:T1446产 地:中国大陆
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T14450Azido-PEG4-hydrazide;化合物 Azido-PEG4-hydrazideINO-464;INO-464
Azido-PEG4-hydrazide is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
价 格:¥电议型 号:T14450产 地:中国大陆
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T14346Aumitin;化合物AumitinAumitin
Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1], and it inhibits mitochondrial respiration by targeting complex I.
价 格:¥电议型 号:T14346产 地:中国大陆
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T14246Amino-PEG5-CH2COOH;化合物 T14246Amino-PEG5-CH2COOH
Amino-PEG5-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14246产 地:中国大陆
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T14218Amicarbazone;胺唑草酮BAY314666|||BAY-MKH 3586;BAY314666|||胺唑草酮|||BAY-MKH 3586
Amicarbazone (BAY-MKH3586; BAY314666) is a potent PSII inhibitor, disrupting photosynthetic electron transport by binding to the Qb domain of photosystem II. This broad-spectrum herbicide is effective through foliar and root application, showcasing rapid absorption and translocation. However, its effectiveness can be compromised by common PSII inhibitor resistance. With an IC50 value indicating high potency, amicarbazone leads to chlorosis, stunted growth, tissue necrosis, and death in sensitive
价 格:¥电议型 号:T14218产 地:中国大陆
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T14208AMD 3465;化合物 T14208GENZ-644494;GENZ-644494
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells.
价 格:¥电议型 号:T14208产 地:中国大陆
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T14202AM-4668;化合物 T14202AM-4668
AM-4668 is a type 2 diabetes GPR40 agonist. For GPR40, in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), the EC50s are 3.6 nM and 36 nM, respectively.
价 格:¥电议型 号:T14202产 地:中国大陆
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T14146AGN 210676;化合物 T14146Simenepag;Simenepag
AGN 210676 is a selective agonist of prostaglandin EP2(EC50 : 5 nM).
价 格:¥电议型 号:T14146产 地:中国大陆
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T14085ABT-046;化合物 T14085ABT-046
ABT-046 is an acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor (IC50= 8 nM)[1]
价 格:¥电议型 号:T14085产 地:中国大陆
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T14046Anandamide;花生四烯酸乙醇胺(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide;花生四烯酸乙醇胺|||(5Z,8Z,
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous system.
价 格:¥电议型 号:T14046产 地:中国大陆
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T13946Turbinaric acid;化合物 T13946Turbinaric acid
Turbinaric acid, a secosqualene carboxylic acid with cytotoxic properties, originates from the brown alga Turbinaria ornata.
价 格:¥电议型 号:T13946产 地:中国大陆
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T13846PROTAC RIPK degrader-2;化合物 T13846PROTAC RIPK degrader-2
PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.
价 格:¥电议型 号:T13846产 地:中国大陆
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T13746KMG-301AM;化合物 T13746KMG-301AM
KMG-301AM, the acetoxy methyl esterified form of KMG-301, facilitates the acquisition of time-course and pseudo-colored images depicting the changes in mitochondrial fluorescence when stained with KMG-301.
价 格:¥电议型 号:T13746产 地:中国大陆
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T13646Desisobutyryl-ciclesonide化合物 T13646CIC-AP|||Ciclesonide active principle
Desisobutyryl-ciclesonide has an affinity for glucocorticoid receptors. Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide.
价 格:¥电议型 号:T13646产 地:中国大陆
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T13615Cinperene;桂哌林R5046;桂哌林|||R5046
Cinperene is an atropine-like compound that can block pilocarpine-induced salivation and lacrimation.
价 格:¥电议型 号:T13615产 地:中国大陆