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T27647J-104132；化合物 T27647L753037|||L 753037|||J104132|||J 104132|||L-753037；L753037|||L 753037|||J104132||
J-104132 is a potetn and selective endothelin A/B receptor antagonist (Ki: cloned human ETA = 0.034 nM; cloned human ETB = 0.104 nM) . In vitro, J-104132 is a potent antagonist of ET-1-induced accumulation of [3H]inositol phosphates in Chinese hamster ovary cells stably expressing cloned human ETA receptors (IC50 = 0.059 nM). Pretreatment with J-104132 prevents the lethal response to ET-1 when administered i.v. (ED50 = 0.045 mg/kg) or p.o. in fed animals (ED50 = 0.35 mg/kg).
价 格：￥电议型 号：T27647产 地：中国大陆
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T27303Farglitazar；法格列扎GI-262570|||GI-2570|||GW 262570X|||GI 262570|||GI262570；GI-262570|||GI-2570|||GW 262
Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer that inhibits stellate cell activation by activating receptor γ via oxidative enzymes proliferators and is used in the study of diabetes.
价 格：￥电议型 号：T27303产 地：中国大陆
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T27228E-3030 free acid；化合物 T27228E-3030|||E3030|||E 3030；E-3030|||E3030|||E 3030
E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Triglyceride- and non-high-density lipoprotein cholesterol-lowering actions of E-3030 involve combined effects on reduction of apo C-III and elevation of lipoprotein lipase, resulting in increased lipolysis.
价 格：￥电议型 号：T27228产 地：中国大陆
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T27036CL-216303 HCl；化合物 T27036DOV-216303|||DOV216303|||CL 216303|||CL-216303|||DOV 216303|||CL216303；DOV-2
CL-216303 HCl, a dopamine transporter inhibitor and a 5-HT inhibitor, is used potentially for the treatment of depression.
价 格：￥电议型 号：T27036产 地：中国大陆
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T26917BTT-3033；化合物 BTT-3033BTT3033|||BTT 3033；BTT3033|||BTT 3033
BTT-3033 is an orally active and potent α2β1 (EC50: 130 nM) inhibitor with an EC50 value of 130 nM. BTT-3033 has an affinity for the α2I domain and inhibits platelet binding to collagen I and cell proliferation.BTT-3033 induces apoptosis and can be used in the study of prostate cancer, BTT-3033 induces apoptosis and can be used to study prostate cancer, inflammation and cardiovascular disease.
价 格：￥电议型 号：T26917产 地：中国大陆
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T26413A 30312；化合物 T26413A-30312|||A30312；A-30312|||A30312
A 30312 is a fused indole, which overcomes multidrug resistance in P388/Adr cells in vitro. It potentiates the cytotoxicity of the antitumor drugs Adriamycin, vincristine and vinblastine in multidrug-resistant cells with no effect on drug-sensitive parent P388 cells.
价 格：￥电议型 号：T26413产 地：中国大陆
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T26323VPC-3033；化合物 T26323VPC-3033
VPC-3033 is an antagonist of the androgen receptor. It acts by inhibiting the LNCaP cell line as well as cell lines with the wild-type androgen receptor.
价 格：￥电议型 号：T26323产 地：中国大陆
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T26303TYT-1；化合物 T26303TYT 1|||NSC298213|||NSC-298213|||NSC 298213；TYT 1|||NSC298213|||NSC-298213|||NSC 298
TYT-1 is the most effective WNV NS3 inhibitor reported to date.
价 格：￥电议型 号：T26303产 地：中国大陆
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T25616Lanepitant 2HCl；拉奈匹坦盐酸盐LY303870 dihydrochloride|||LY 303870 dihydrochloride|||LY-303870 dihydrochlor
Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflammation and pain transmission, and can be used in the study of painful neuropathic disorders, such as migraines.
价 格：￥电议型 号：T25616产 地：中国大陆
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T25615Lanepitant；拉奈匹坦LY303870|||LY-303870|||LY 303870；LY303870|||LY-303870|||LY 303870
Lanepitant (LY303870) is a nonpeptide neurokinin-1 (NK-1) antagonist with analgesic activity that inhibits neurogenic dura mater inflammation and is used for the prevention of migraine.
价 格：￥电议型 号：T25615产 地：中国大陆
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T25303Deltamycin A1；化合物 T25303Deltamycin A1
Deltamycin A1 is a novel macrolide antibiotic.
价 格：￥电议型 号：T25303产 地：中国大陆
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T24758SAR127303；化合物 T24758SAR-127303|||SAR 127303；SAR-127303|||SAR 127303
SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.
价 格：￥电议型 号：T24758产 地：中国大陆
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T24466Milademetan free base；化合物 T24466DS3032B|||DS-3032|||DS3032|||DS 3032|||DS 3032B|||DS-3032B；DS3032B||
Milademetan (DS-3032b or DS-3032) is a potent and selective MDM2 inhibitor with potential antineoplastic activity. Milademetan (p.o.) binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53.
价 格：￥电议型 号：T24466产 地：中国大陆
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T24419LY 806303；化合物 T24419L 806303|||LY806303|||L-806303|||LY-806303|||L806303；L 806303|||LY806303|||L-806
LY 806303 is a highly selective thrombin inhibitor.
价 格：￥电议型 号：T24419产 地：中国大陆
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T2434LY 303511；化合物LY 303511LY 303511
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
价 格：￥电议型 号：T2434产 地：中国大陆
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T24303L 647318；化合物 T24303L-647318|||L 647,318|||L-647,318|||L647,318|||L647318；L-647318|||L 647,318|||L-64
L 647318 is an inhibitor of Hydroxymethylglutaryl-CoA reductase.
价 格：￥电议型 号：T24303产 地：中国大陆
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T23682AHR-16303B oxalate；化合物 T23682AHR 16303B oxalate；AHR 16303B oxalate
AHR-16303B oxalate is a novel antagonist of 5-HT2 receptors.
价 格：￥电议型 号：T23682产 地：中国大陆
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T2337BMS-303141；化合物BMS-303141BMS 303141；BMS 303141
BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).
价 格：￥电议型 号：T2337产 地：中国大陆
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T2332Elvitegravir；埃替格韦GS-9137|||EVG|||D06677|||JTK-303；埃替格韦|||GS-9137|||EVG|||D06677|||JTK-303
Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.
价 格：￥电议型 号：T2332产 地：中国大陆
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T23303S-Sulfo-L-cysteine sodium salt；L-半胱氨酸硫酸氢酯单钠盐S-Sulfo-L-cysteine sodium salt
S-Sulfo-L-cysteine sodium salt shows a weak affinity for mGluR1α and mGluR5a at high concentrations and has potential antioxidant activity.
价 格：￥电议型 号：T23303产 地：中国大陆
