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产品数：86101
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T7303LIXIVAPTANVPA 985,LIXIVAPTAN,VPA985,inhibit,Inhibitor,Vasopressin Receptor
Lixivaptan is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM)
价 格：￥电议型 号：T7303产 地：中国大陆
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T22303Dasatinib hydrochloride
Dasatinib hydrochloride (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride hydrochloride also induces Apoptosis and Autophagy.
价 格：￥电议型 号：T22303产 地：中国大陆
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T7013VorapaxarProtease Activated Receptor (PAR),Inhibitor,SCH-530348,Vorapaxar,SCH530348,Thrombin recepto
Vorapaxar (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).
价 格：￥电议型 号：T7013产 地：中国大陆
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T8173Delafloxacin meglumineWQ3034,inhibit,ABT492,ABT-492,Delafloxacin meglumine,Inhibitor,RX3341,RX-3341,
Delafloxacin meglumine is a broad-spectrum fluoroquinolone antibiotic
价 格：￥电议型 号：T8173产 地：中国大陆
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T7152Ravuconazoleinhibit,ER30346,BMS207147,Ravuconazole,BMS 207147,Fungal,ER 30346,Inhibitor
Ravuconazole is a potent triazole antifungal that potently inhibits a wide range of fungi.
价 格：￥电议型 号：T7152产 地：中国大陆
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T22835H2L5186303
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
价 格：￥电议型 号：T22835产 地：中国大陆
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T14303Alrizomadlin
Alrizomadlin is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner.
价 格：￥电议型 号：T14303产 地：中国大陆
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T13303Virginiamycin M1
Virginiamycin M1 is a macrocyclic lactone peptide antibiotic and is a member of the streptogramin A group of antibiotics.
价 格：￥电议型 号：T13303产 地：中国大陆
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T13037Sulindac sulfideSulindac sulfide
Sulindac sulfide is an inhibitor of noncompetitive γ-secretase(IC50 of 20.2 μM for γ42-secretase activity).
价 格：￥电议型 号：T13037产 地：中国大陆
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T7653JNJ 303JNJ-303,JNJ 303,inhibit,Potassium Channel,JNJ303,Inhibitor,KcsA
JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).
价 格：￥电议型 号：T7653产 地：中国大陆
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TP1199LUrotensin I acetate (83930-33-0 Free base)Urotensin I acetate (83930330 Free base),Urotensin I aceta
Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2].
价 格：￥电议型 号：TP1199L产 地：中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格：￥电议型 号：T9303产 地：中国大陆
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T6633RanolazineNa+ channels,CVT-303,Ca2+ channels,inhibit,Sodium Channel,Ranolazine,Inhibitor,Calcium Cha
Ranolazine is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the intracellular sodium level.
价 格：￥电议型 号：T6633产 地：中国大陆
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T6521GSK 2830371GSK-2830371,Inhibitor,GSK 2830371,Phosphatase,inhibit
GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.
价 格：￥电议型 号：T6521产 地：中国大陆
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T9723WAY-303290Ionotropic glutamate receptors,Inhibitor,iGluR,WAY303290,benzothiophene derivative,chronic
WAY-303290 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.
价 格：￥电议型 号：T9723产 地：中国大陆
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T30355Benzeneboronic acid
Benzeneboronic acid is a boronic acid that is used in Mizoroki-Heck and Suzuki-Miyaura coupling reactions.
价 格：￥电议型 号：T30355产 地：中国大陆
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T11087DOV-216,303 Free Baseinhibit,SLC6A4,Serotonin Transporter,DOV 216,303 Free Base,5-HTT,DAT,DOV-216,30
DOV-216,303 Free Base is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
价 格：￥电议型 号：T11087产 地：中国大陆
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T6840LFRAX486 HCL(1232030-35-1 free base)FRAX486 HCL(1232030351 free base),FRAX486 HCL(1232030 35 1 free b
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
价 格：￥电议型 号：T6840L产 地：中国大陆
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T6303LCCT128930 hydrochlorideCCT128930 hydrochloride(885499-61-6 Free base)
CCT128930 hydrochloride is a potent and selective inhibitor of AKT with IC50 of 6 nM. CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50:
价 格：￥电议型 号：T6303L产 地：中国大陆
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T6303CCT128930
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.
价 格：￥电议型 号：T6303产 地：中国大陆
