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  • T73039CYP1B1-IN-3；化合物 CYP1B1-IN-3CYP1B1-IN-3

    CYP1B1-IN-3 is a potent, selective inhibitor of CYP1B1, exhibiting IC50 values of 6.6 nM for CYP1B1, 347.3 nM for CYP1A1, and >10000 nM for CYP1A2. It also impedes cell migration and invasion, and inhibits the P-gp, AKT/ERK, FAK/SRC, and EMT pathways [1].

    价 格：￥电议型 号：T73039产 地：中国大陆

  • T73038HSP90-IN-19；化合物 HSP90-IN-19HSP90-IN-19

    HSP90-IN-19 is a potent inhibitor of heat shock protein 90 (Hsp90), exhibiting inhibitory activity with an IC50 of 0.27 μM. It is utilized in the research of viral infections, neurodegenerative diseases, and inflammation [1].

    价 格：￥电议型 号：T73038产 地：中国大陆

  • T73037HSP90-IN-18；化合物 HSP90-IN-18HSP90-IN-18

    HSP90-IN-18 is a potent inhibitor of heat shock protein 90 (Hsp90), demonstrating significant inhibitory activity with an IC50 value of 0.39 μM. It is applicable in the research of viral infections, neurodegenerative diseases, and inflammation.

    价 格：￥电议型 号：T73037产 地：中国大陆

  • T73036hCA IX-IN-2；化合物 hCA IX-IN-2hCA IX-IN-2

    hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative activity.

    价 格：￥电议型 号：T73036产 地：中国大陆

  • T73035STAT3-IN-15；化合物 STAT3-IN-15STAT3-IN-15

    STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-β1-induced migration and deformation of epithelial cells and prevents epithelial-mesenchymal transition (EMT), offering a multifaceted approach against IPF.

    价 格：￥电议型 号：T73035产 地：中国大陆

  • T73034NLRP3-IN-12；化合物 NLRP3-IN-12NLRP3-IN-12

    NLRP3-IN-12 is a specific inhibitor of the NLRP3 inflammasome, effectively reducing IL-1β release by targeting the NLRP3 protein, and demonstrating an IC50 of 0.45 μM. This compound is utilized in the research of inflammatory bowel disease.

    价 格：￥电议型 号：T73034产 地：中国大陆

  • T73033TRK II-IN-1；化合物 TRK II-IN-1TRK II-IN-1

    TRK II-IN-1 is a potent type II inhibitor of tropomyosin receptor kinases (TRK), demonstrating inhibitory half-maximal inhibitory concentrations (IC50s) of 3.3, 6.4, 4.3, and 9.4 nM against TRKA, TRKB, TRKC, and the mutant TRKA G667C, respectively. Additionally, this compound exhibits IC50 values of 1.3 nM against FLT3, 9.9 nM against RET, and 71.1 nM against VEGFR2. TRK II-IN-1 primarily serves as a research tool for studying TRK-driven cancers [1].

    价 格：￥电议型 号：T73033产 地：中国大陆

  • T73032MtInhA-IN-1；化合物 MtInhA-IN-1MtInhA-IN-1

    MtInhA-IN-1 is a potent, selective, and orally active inhibitor targeting the Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA), demonstrating an IC50 of 0.23 μM. It exhibits strong efficacy against the M. tuberculosis H37Rv strain, with a MIC value of 0.4 μM.

    价 格：￥电议型 号：T73032产 地：中国大陆

  • T73031HDAC6-IN-14；化合物 HDAC6-IN-14HDAC6-IN-14

    HDAC6-IN-14, an inhibitor of HDAC6 (HDAC), exhibits high selectivity with an IC50 value of 42 nM, demonstrating over 100-fold selectivity compared to HDAC1, HDAC2, HDAC3, and HDAC4.

    价 格：￥电议型 号：T73031产 地：中国大陆

  • T73030hCAIX-IN-14；化合物 hCAIX-IN-14hCAIX-IN-14

    hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM [1] .

    价 格：￥电议型 号：T73030产 地：中国大陆

  • T7303LIXIVAPTAN；利伐普坦VPA-985|||WAY-VPA 985；VPA-985|||利伐普坦|||WAY-VPA 985

    Lixivaptan (VPA-985) is an orally active and selective vasopressin receptor V2 antagonist(Ki = 2.3 nM)

    价 格：￥电议型 号：T7303产 地：中国大陆

  • T72303Antibacterial agent 124；化合物 Antibacterial agent 124Antibacterial agent 124

    Antibacterial agent 124 is a potent inhibitor of bacterial prolyl-tRNA synthetase (ProRS), specifically targeting Staphylococcus aureus ProRS (Sa ProRS) with an inhibitory concentration (IC50) of 0.18 μM.

    价 格：￥电议型 号：T72303产 地：中国大陆

  • T71876F1386-0303；化合物 F1386-0303F1386-0303

    F1386-0303 is a novel potent and selective MAP4K4 inhibitor.

    价 格：￥电议型 号：T71876产 地：中国大陆

  • T7152Ravuconazole；雷夫康唑BMS-207147|||ER-30346；立福康唑|||雷夫康唑|||BMS-207147|||ER-30346

    Ravuconazole (ER-30346) is a potent triazole antifungal that potently inhibits a wide range of fungi.

    价 格：￥电议型 号：T7152产 地：中国大陆

  • T71303Flufenamic Acid-d4；化合物 Flufenamic Acid-d4Flufenamic Acid-d4

    Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 ?M for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear

    价 格：￥电议型 号：T71303产 地：中国大陆

  • T70615TAS-303；化合物 TAS-303TAS-303

    TAS-303 is a selective norepinephrine reuptake inhibitor which displays significant norepinephrine transporter (NET) inhibitory activity toward serotonin or dopamine transporters. Radioligand-binding studies showed that TAS-303 selectively and potently inhibited [3H]norepinephrine binding to the human NET.

    价 格：￥电议型 号：T70615产 地：中国大陆

  • T70471Cgs 26303；化合物 Cgs 26303Cgs 26303

    Cgs 26303 is a potent non-peptidic inhibitor of neutral endopeptidase capable of protecting atrial natriuretic peptide from enzymatic degradation.

    价 格：￥电议型 号：T70471产 地：中国大陆

  • T70393PF-303；化合物 PF-303PF-303

    PF-303 is a covalent-reversible BTK inhibitor. Inhibitors of Bruton´s tyrosine kinase (BTK) possess much promise for the treatment of oncologic and autoimmune indications.

    价 格：￥电议型 号：T70393产 地：中国大陆

  • T70303N-Boc-15-aminopentadecanoic acid；化合物 N-Boc-15-aminopentadecanoic acidN-Boc-15-aminopentadecanoic aci

    N-Boc-15-aminopentadecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

    价 格：￥电议型 号：T70303产 地：中国大陆

  • T7013Vorapaxar；沃拉帕沙SCH 530348|||MK-5348；SCH 530348|||MK-5348|||沃拉帕沙

    Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).

    价 格：￥电议型 号：T7013产 地：中国大陆

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