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T39548Amustaline dihydrochloride;Amustaline dihydrochlorideS-303 dihydrochloride;S-303 dihydrochloride
Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key elements: an acridine anchor (a non-covalently bonding intercalator targeting nucleic acids), an effector (a bis-alkylator group that interacts with nucleophiles), and a linker (a flexible carbon chain with a labile ester bond, hydrolyzing at neutral pH to non-reactive products).
价 格:¥电议型 号:T39548产 地:中国大陆
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T38303Apramycin (Nebramycin II);Apramycin (Nebramycin II)Apramycin (Nebramycin II)
Apramycin(Nebramycin II) is an aminoglycoside antibiotic used in veterinary medicine.Target: Apramycin stands out among aminoglycosides for its mechanism of action which is based on blocking translocation and its ability to bind also to the eukaryotic decoding site despite differences in key residues required for apramycin recognition by the bacterial target. The drug binds in the deep groove of the RNA which forms a continuously stacked helix comprising non-canonical C.A and G.A base pairs and
价 格:¥电议型 号:T38303产 地:中国大陆
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T373035-OxoETE;5-OxoETE5-KETE|||5-OxoETE;5-KETE|||5-OxoETE
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.[1] It stimulates cytosolic calcium levels in neutrophils with an EC50 value of 2 nM.[2] 5-OxoETE selectively stimulates the migration and degranulation of eosinophils and activates the MAPK pathway in stimulated neutrophils via a specific G protein-coupled receptor.[3],[4],[5],[6]
价 格:¥电议型 号:T37303产 地:中国大陆
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T3633Crenigacestat;化合物CrenigacestatLY3039478;LY3039478
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested. Crenigacestat effectively inhibits mutant Notch receptor activity. In a xenograft tumor model, Crenigacestat inhibited expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment.
价 格:¥电议型 号:T3633产 地:中国大陆
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T36303Psammaplin A;Psammaplin APsammaplin A
Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobial effects against Gram-positive bacteria and inhibits both DNA synthesis and DNA gyrase activity, also demonstrating antitumor activity[1][2].
价 格:¥电议型 号:T36303产 地:中国大陆
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T3558EBE-A22;化合物EBE-A22PD153035 Analog 63;PD153035 Analog 63
EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.
价 格:¥电议型 号:T3558产 地:中国大陆
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T35303Zephyranthine;化合物 T35303Zephyranthine
Zephyranthine is a biochemical.
价 格:¥电议型 号:T35303产 地:中国大陆
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T34752Samelisant dihydrochloride;Sardomozide 盐酸盐SUVN-G3031|||SUVN-G 3031|||SUVN G3031|||SUVN-G3031 HCl;SUV
Samelisant dihydrochloride (SUVN-G3031) is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating disorders, and pain.
价 格:¥电议型 号:T34752产 地:中国大陆
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T34457RX 783030;化合物 T34457RX783030|||RX-783030;RX783030|||RX-783030
RX 783030 is an enkephalin analog that is stabilized.
价 格:¥电议型 号:T34457产 地:中国大陆
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T34231Quinterenol sulfate;化合物 T34231CP-10,303-8|||Quinprenaline sulfate|||CP 10,303-8;CP-10,303-8|||Quinpr
Quinoline sulfate has a bronchiectasis effect on patients with asthma.
价 格:¥电议型 号:T34231产 地:中国大陆
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T34170Proxazole citrate;化合物 T34170NSC-303872|||NSC 303872|||NSC303872;NSC-303872|||NSC 303872|||NSC303872
Proxazole citrate is a biochemical.
价 格:¥电议型 号:T34170产 地:中国大陆
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T33890PBB3;化合物 T33890PBB-3|||J3.303.052E|||PBB 3;PBB-3|||J3.303.052E|||PBB 3
PBB3 is a tau-specific PET tracer.
价 格:¥电议型 号:T33890产 地:中国大陆
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T3336Rg3039;化合物Rg3039PF-06687859;PF-06687859
Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RG3039 improves motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models.
价 格:¥电议型 号:T3336产 地:中国大陆
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T33341Methyl piperonylate;化合物 T33341AI3-30387|||AI330387|||AI3 30387;AI3-30387|||AI330387|||AI3 30387
Methyl piperonylate is a biochemical.
价 格:¥电议型 号:T33341产 地:中国大陆
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T33037Lyoniol-A;化合物 T33037Lyoniol-A
Lyoniol-A is a toxic component from poisonous tree in Japan(Lyonia ovalifolia var. elliptica).
价 格:¥电议型 号:T33037产 地:中国大陆
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T33036Lyoniol B;化合物 T33036LyoniolB|||Lyoniol-B|||Deacetyllyoniatoxin;LyoniolB|||Lyoniol-B|||Deacetyllyonia
Lyoniol B is a grayanane diterpenoids from the leaves of Craiobiodendron yunnanense.
价 格:¥电议型 号:T33036产 地:中国大陆
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T33035Lyofolic acid;化合物 T33035Lyofolic acid
Lyofolic acid is a bioactive chemical.
价 格:¥电议型 号:T33035产 地:中国大陆
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T33034Lyngbyatoxin B;化合物 T33034Lyngbyatoxin B
Lyngbyatoxin B is an irritant form Lyngbya majuscula.
价 格:¥电议型 号:T33034产 地:中国大陆
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T33033Lyngbyatoxin A;化合物 T33033Lyngbyatoxin A
Lyngbyatoxin A is an indole alkaloid from blue-green alga Lyngbya majuscula Gomont; responsible for dermatitis known as "swimmers´ itch" in Hawaii.
价 格:¥电议型 号:T33033产 地:中国大陆
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T33032Lynestrenol mixture with mestranol;化合物 T33032Lynestrenol mixture with mestranol
Lynestrenol mixture with mestranol is a bioactive chemical.
价 格:¥电议型 号:T33032产 地:中国大陆