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  • T60523Agomelatine hydrochloride

    Agomelatine hydrochloride (S-20098 hydrochloride) is a specific MT1 and MT2 receptor agonist with Ki of 0.1 nM for CHO-hMT1, 0.06 nM for HEK-hMT1, 0.12 nM for CHO-hMT2, and 0.27 nM for HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective antagonist of a 5-HT2C receptor with pKis of 6.4 and 6.2 for native (porcine) and cloned, human 5-HT2C receptors, respectively [2].

    价 格：￥电议型 号：T60523产 地：中国大陆

  • T67864TH1760

    TH1760 is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM). TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia effect of thiopurine.

    价 格：￥电议型 号：T67864产 地：中国大陆

  • T64392WAY-601035WAY601035???

    WAY-601035 is a specific inhibitor of PI3Kγ.

    价 格：￥电议型 号：T64392产 地：中国大陆

  • T23602ABC99

    ABC99 is a selective irreversible inhibitor of the wnt-deacylating enzyme. ABC99 inhibited NOTUM (IC50: 13 nM). It also showed excellent selectivity across the serine hydrolase family.

    价 格：￥电议型 号：T23602产 地：中国大陆

  • TQ0210Savolitinibinhibit,Savolitinib,AZD 6094,Inhibitor,c-Met/HGFR,AZD6094,HMPL504,HMPL 504

    Savolitinib (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met).

    价 格：￥电议型 号：TQ0210产 地：中国大陆

  • T60073WAY-658650WAY 658650,WAY658650

    WAY-658650 has antibacterial activity against Mycobacterium tuberculosis.

    价 格：￥电议型 号：T60073产 地：中国大陆

  • T7360GSK2018682LPL Receptor,Inhibitor,inhibit,Lysophospholipid Receptor,GSK-2018682,GSK 2018682,GSK201868

    GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).

    价 格：￥电议型 号：T7360产 地：中国大陆

  • TN3604CarveolInhibitor,Endogenous Metabolite,Carveol,inhibit

    (-)-Carveol, mixture of isomers is a monocyclic monoterpenic alcohol, present in essential oils of plant species such as Cymbopogon giganteus, Illicium pachyphyllum and in spices such as Carum carvi (cumin).

    价 格：￥电议型 号：TN3604产 地：中国大陆

  • T38715MSDC-0602K

    MSDC-0602K (Azemiglitazone potassium), a PPARγ -sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC 50 of 18.25 μM. MSDC-0602K modulates the mitochondrial pyruvate carrier (MPC). MSDC-0602K can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide.

    价 格：￥电议型 号：T38715产 地：中国大陆

  • T7525DidoxInhibitor,DNA/RNA Synthesis,inhibit,Didox,NSC 324360,NSC324360

    Didox is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia.

    价 格：￥电议型 号：T7525产 地：中国大陆

  • T60231N-[2-nitro-4-(trifluoromethyl)phenyl]piperazineN[2NITRO4(TRIFLUOROMETHYL)PHENYL]PIPERAZINE

    N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine is a bioactive substances.

    价 格：￥电议型 号：T60231产 地：中国大陆

  • T60048WAY-640509WAY 640509,WAY640509

    WAY-640509 is a glucocerebrosidase inhibitor.

    价 格：￥电议型 号：T60048产 地：中国大陆

  • T60055Chromeceptin

    Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.

    价 格：￥电议型 号：T60055产 地：中国大陆

  • T9560MAO-B-IN-2MAO B IN 2,MAOBIN2

    MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property.

    价 格：￥电议型 号：T9560产 地：中国大陆

  • T60086TTBK1-IN-2

    TTBK1-IN-2 is an inhibitor of Tau-Tubulin kinase (TTBK1) with IC50s of 0.24 and 4.22 ?M. TTBK1-IN-2 reduces TDP-43 phosphorylation both in cell cultures and the spinal cord of transgenic TDP-43 mice.

    价 格：￥电议型 号：T60086产 地：中国大陆

  • T8960MONNACl-Channels,inhibit,MONNA,Inhibitor,Chloride Channel

    MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.

    价 格：￥电议型 号：T8960产 地：中国大陆

  • T26035rac-NBI-74330

    rac-NBI-74330 is an effective and selective CXCR3 antagonist.

    价 格：￥电议型 号：T26035产 地：中国大陆

  • T60105Enpp-1-IN-14

    ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.

    价 格：￥电议型 号：T60105产 地：中国大陆

  • T9180LUF6096

    LUF6096 is a potent allosteric enhancer of the adenosine A3 receptor. LUF6096 is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.

    价 格：￥电议型 号：T9180产 地：中国大陆

  • T60225Imidodicarbonimidic diamide, N-[4-(10,15,20-triphenyl-21H,23H-porphin-5-yl)phenyl]-, hydrochloride (

    Imidodicarbonimidic diamide, N-?[4-?(10,?15,?20-?triphenyl-?21H,?23H-?porphin-?5-?yl)?phenyl]?-?, hydrochloride (1:1) is a phototoxic agent with anti-proliferative activity.

    价 格：￥电议型 号：T60225产 地：中国大陆

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