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T6460Cysteamine hydrochloridecystinosis,antioxidant,2-Aminoethanethiol,nephropathic,Autophagy,Apoptosis,I
Cysteamine is an agent for the treatment of nephropathic cystinosis and an antioxidant.
价 格：￥电议型 号：T6460产 地：中国大陆
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TP1600LIα52 acetate(137756-45-7 free base)Iα52 acetate(137756457 free base),Iα52 acetate(137756 45 7 free b
Iα52 acetate is a naturally processed peptide encompassed the residues 52-68 of the murine I-Eα chain and may contribute to selection of immature T cells.
价 格：￥电议型 号：TP1600L产 地：中国大陆
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T36036CAY10786Inhibitor,Huntington’s disease,inhibit,HdhQ140,CAY10786,CAY-10786
CAY10786 is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).
价 格：￥电议型 号：T36036产 地：中国大陆
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T60129MT189
MT189 is a potent tubulin polymerization inhibitor, with an IC50 of 3.41 μM. Antiproliferative agent-14 has excellent antiproliferative activity. Antiproliferative agent-14 possess the ability to arrest cells at G2/M phases of the cell cycle.
价 格：￥电议型 号：T60129产 地：中国大陆
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T7316LY2828360Inhibitor,LY2828360,inhibit,LY-2828360,LY 2828360,Cannabinoid Receptor
LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPγS binding assay (EC50s = 20.1 and >100,000 nM, respectively).
价 格：￥电议型 号：T7316产 地：中国大陆
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T60079GNE-064
GNE-064 is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 μM and inhibits SMARCA2 with an EC50 of 0.10 μM. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 μM for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of drug synthesis.
价 格：￥电议型 号：T60079产 地：中国大陆
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TP1348FC131 TFA (606968-52-9 free base)FC131 TFA (606968529 free base),FC131 TFA (606968 52 9 free base),F
FC131 TFA is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.
价 格：￥电议型 号：TP1348产 地：中国大陆
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T6608NMDAinhibit,iGluR,Inhibitor,NMDA,Ionotropic glutamate receptors,Endogenous Metabolite
N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors.
价 格：￥电议型 号：T6608产 地：中国大陆
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T601264-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-meth
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.
价 格：￥电议型 号：T60126产 地：中国大陆
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T9273SI 60SI 60
Sanaid SI 60 is an aromatic sulfonium salt and is initiator for thermosetting polymerization at low temperature.
价 格：￥电议型 号：T9273产 地：中国大陆
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T60217TAS1553TAS1553
TAS1553 is a potent, orally active protein–protein interaction (PPI) inhibitor with an IC 50 values of 0.0396 μM. TAS1553 inhibits DNA replication and reduces intracellular dATP pool. TAS1553 induces apoptosis and can be used for cancer research [1].
价 格：￥电议型 号：T60217产 地：中国大陆
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T60078NSC2805
NSC2805 is an inhibitor of WWP2, an E3 ubiquitin ligase with an IC50 of 0.38 μM. NSC2805 can be used in anticancer studies.
价 格：￥电议型 号：T60078产 地：中国大陆
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T60051VPC-18005VPC 18005,inhibit,ETS,VPC18005,ERG,VPC-18005,PNT1B,cancer,prostate,Inhibitor
VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.
价 格：￥电议型 号：T60051产 地：中国大陆
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T13360XRK3F2XRK3F2,XRK-3F2
XRK3F2 is an inhibitor of the p62-ZZ domain, blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo.
价 格：￥电议型 号：T13360产 地：中国大陆
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T60013GA-017GA017,GA 017
GA-017 is a potent and selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2), with IC 50 values of 4.10 and 3.92 nM, respectively. GA-017 is an activator of cell proliferation. GA-017 promotes YAP/TAZ activation and nuclear translocation. GA-017 promotes cell growth under 3D culture conditions. GA-017 enhances the ex vivo formation of mouse intestinal organoids [1].
价 格：￥电议型 号：T60013产 地：中国大陆
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T6928Pantoprazolerelease,exosome,orally,Doxorubicin,Autophagy,SKF 96022,Inhibitor,A431,BY-1023,H+/K+-ATPa
Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
价 格：￥电议型 号：T6928产 地：中国大陆
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TP1866Lβ-amyloid 1-11 acetate(190436-05-6 free base)βamyloid 111 acetate(190436056 free base),β amyloid 1 1
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.
价 格：￥电议型 号：TP1866L产 地：中国大陆
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T6730WAY-600inhibit,Inhibitor,mTOR,WAY 600,WAY-600,Mammalian target of Rapamycin
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
价 格：￥电议型 号：T6730产 地：中国大陆
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T9533BC-LI-0186Aminoacyl-tRNA Synthetase,RagD,rapamycin-resistant,BCLI0186,tRNA Synthetase, aaRS,H460,KRA
BC-LI-0186 is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protein D (RagD) with IC50 of 46.11 nM. BC-LI-0186 competitively binds the RagD interaction site of LRS with Kd of 42.1 nM and has no effect on LRS-vps34, LRS-eprs, RagB-RagD association, mTORC1 complex formation. BC-LI-0186 potently inhibits the activity of tumor-associated MTOR mutants and the growth of rapamycin-resistant cancer cells. BC-LI-0186 can be used for lung c
价 格：￥电议型 号：T9533产 地：中国大陆
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T60144TDI-011536TDI011536
TDI-011536 is a potent Lats kinase inhibitor. TDI-011536 interrupts Hippo-Yap signaling and initiates the proliferation of lesioned heartmuscle cells. TDI-011536 can be used in studies of organ conservation and regeneration.
价 格：￥电议型 号：T60144产 地：中国大陆
