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T12777RTC-5
RTC-5 (TRC-382) is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling.
价 格:¥电议型 号:T12777产 地:中国大陆
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T67756ISRIB-A15
ISRIB-A15 is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
价 格:¥电议型 号:T67756产 地:中国大陆
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TP1775LLL-37, Human acetate(154947-66-7 free base)LL37, Human acetate(154947667 free base),LL 37, Human ace
LL-37, Human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity.
价 格:¥电议型 号:TP1775L产 地:中国大陆
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T30677LC15AlkOPP Tetrabutylamine salt(946615-44-7 Free base)
C15AlkOPP Tetrabutylamine salt is a “clickable” alkyne-modified analogs of the lipid substrates farnesyl diphosphate (FPP).
价 格:¥电议型 号:T30677L产 地:中国大陆
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T67745CB2R/FAAH?modulator-2CB2R/FAAH?modulator2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67745产 地:中国大陆
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T17197UCL 2077UCL-2077,Inhibitor,UCL 2077,UCL2077,inhibit
UCL 2077 is a subtype-selective blocker of the epilepsy-associated KCNQ channels and it also is a selective slow-afterhyperpolarization channel blocker,with IC50 of 500 nM in hippocampal neurons in culture, having minimal effects on Ca2+ channels, action potentials, input resistance, and the medium afterhyperpolarization.
价 格:¥电议型 号:T17197产 地:中国大陆
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T8866GW779439XApoptosis,pazolopyridazine,threonine,cancer,Inhibitor,inhibit,lactam,GW-779439X,derivatives
GW779439X is an inhibitor of CDK.
价 格:¥电议型 号:T8866产 地:中国大陆
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T8477IQ-3Inhibitor,IL-6,inhibit,TNF-α,IQ-3,JNK,IQ 3,IQ3,IL-1β,IL-1α
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.
价 格:¥电议型 号:T8477产 地:中国大陆
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T8772Sumaresinolic AcidSumaresinolic Acid
Sumaresinolic Acid is a chemical compound
价 格:¥电议型 号:T8772产 地:中国大陆
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T8779HBT1HBT 1,Ionotropic glutamate receptors,HBT-1,BDNF,LBD,inhibit,glutamate,AMPA,primary neurons,S518,
HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
价 格:¥电议型 号:T8779产 地:中国大陆
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TN6774Emodin 6-O-β-D-glucosideatherosclerosis,Emodin 6OβDglucoside,diabetic,Reynoutria,active,Inhibitor,ba
Emodin 6-O-β-D-glucoside can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.
价 格:¥电议型 号:TN6774产 地:中国大陆
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TP1925LtcY-NH2 TFA(327177-34-4 free base)tcY-NH-2 TFA(327177-34-4 free base),tcY NH2 TFA(327177 34 4 free b
tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
价 格:¥电议型 号:TP1925L产 地:中国大陆
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T9122XL177AMCF7,XL177A,Deubiquitinase,inhibit,Inhibitor,cancer,XL-177A,DUBs,p53,USP7
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
价 格:¥电议型 号:T9122产 地:中国大陆
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T67709HispolonHISPOLON(P)
Hispolon is a polyphenol. Hispolon can be isolated from Phellinus linteus. Hispolon exhibits anticancer, antidiabetic, antiviral, hepatoprotective, antioxidant, and anti-inflammatory activities.
价 格:¥电议型 号:T67709产 地:中国大陆
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T6320GDC-0879GDC 0879;GDC0879;AR-00341677
GDC-0879 is a novel, potent and selective B-Raf inhibitor with IC50 of 0.13 nM with activity against c-Raf as well.
价 格:¥电议型 号:T6320产 地:中国大陆
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T6277DoramapimodBIRB 796;达马莫德;度马莫德
Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
价 格:¥电议型 号:T6277产 地:中国大陆
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T6276KU-57788NU7441
NU7441 (KU-57788) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).
价 格:¥电议型 号:T6276产 地:中国大陆
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T6271TipifarnibZarnestra;IND 58359;R115777;替吡法尼
Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting
价 格:¥电议型 号:T6271产 地:中国大陆
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T6224Iniparib3-硝基-4-碘苯甲酰胺;BSI-201;IND-71677;NSC-746045
Iniparib (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).
价 格:¥电议型 号:T6224产 地:中国大陆
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T6203Saxagliptin沙克列汀;沙格列汀;BMS-477118;Onglyza
Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
价 格:¥电议型 号:T6203产 地:中国大陆