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T4377PimodivirVX-787
Pimodivir, an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit.
价 格:¥电议型 号:T4377产 地:中国大陆
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T4200Sacubitril hemicalcium saltAHU-377 (hemicalcium salt);AHU377 calcium salt;LCZ696中间体
AHU-377 hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696. AHU377 is a prodrug of LBQ657, which is an inhibitor of the zinc metallopeptidase neprilysin. Neprilysin degrades a varie
价 格:¥电议型 号:T4200产 地:中国大陆
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T40477Dichlormid
Dichlormid is a herbicide safener. Dichlormid up-regulates expression of ZmGST27 and ZmMRP1 and increases ZmGT1 [1] [2] .
价 格:¥电议型 号:T40477产 地:中国大陆
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T40377NicotredoleTryptamide;尼可曲多;尼可曲朵
Nicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity [1] [2] [3] .
价 格:¥电议型 号:T40377产 地:中国大陆
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T40130Nur77 modulator 1Nur77 modulator 1
Nur77 modulator 1 is a good Nur77 binder (K D = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell apoptosis. Anti-hepatoma activity
价 格:¥电议型 号:T40130产 地:中国大陆
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T3S1775TectochrysinTechtochrysin;Techtochrysine;NSC 80687;柚木柯因
1. Tectochrysin has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrysin leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of
价 格:¥电议型 号:T3S1775产 地:中国大陆
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T3977Lifitegrast立他司特;利非司特;SAR 1118;SHP-606
Lifitegrast is a lymphocyte, function-associated antigen-1 antagonist.
价 格:¥电议型 号:T3977产 地:中国大陆
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T39477Calcium trinatrium diethylenetriaminepentaacetic acid hydrateCa-DTPA trisodium salt hydrate;Calcium
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic
价 格:¥电议型 号:T39477产 地:中国大陆
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T3877Esculentoside A
Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmune disease through modulation on T c
价 格:¥电议型 号:T3877产 地:中国大陆
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T37793A2B receptor antagonist 2A2B receptor antagonist 2
A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
价 格:¥电议型 号:T37793产 地:中国大陆
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T37792A2A receptor antagonist 1A2A receptor antagonist 1
A2A receptor antagonist 1 is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.
价 格:¥电议型 号:T37792产 地:中国大陆
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T3779Crocin II西红花苷II;藏红花;Tricrocin;Crocin B;Crocetin gentiobiosylglucosyl ester;Crocin 2
Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin can ameliorate CCl4-induced liver injury
价 格:¥电议型 号:T3779产 地:中国大陆
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T377842,6-Dimethylquinoline
2,6-Dimethylquinoline is a natural product extracted from the roots of Peucedantu praeruptorum. 2,6-Dimethylquinoline is an inhibitor of CYP1A2 and CYP2B6 with an IC50 of 3.3 and 480 ?M, respectively.
价 格:¥电议型 号:T37784产 地:中国大陆
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T3777Praeruptorin A白花前胡甲素;(+)-Praeruptorin A
Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
价 格:¥电议型 号:T3777产 地:中国大陆
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T3776RhapontigeninProtigenin;丹叶大黄素
Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol
价 格:¥电议型 号:T3776产 地:中国大陆
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T37753Aureusimine B
Aureusimine B, a Calpain inhibitor, is produced by Staphylococcus aureus biofilms and could be a potential biomarker for S. aureus biofilm-based infections.
价 格:¥电议型 号:T37753产 地:中国大陆
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T3774Gracillin山药;纤细薯蓣皂苷
Gracillin can induce cell cycle arrest, oxidative stress, and apoptosis in HL60 cells, and has the potential to be developed as an antitumor agent. Gracillin can be selected as lead compounds for the development of new drugs against I. multifiliis.
价 格:¥电议型 号:T3774产 地:中国大陆
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T37734AMPA receptor modulator-2
AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.
价 格:¥电议型 号:T37734产 地:中国大陆