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T8549HEPESInhibitor,buffering,lysosome,zwitterionic,culture,HEPES,chemical,biogenesis,inhibit,cell
HEPES is a zwitterionic sulfonic acid buffering agent, commonly used to uphold a neutral pH of basal medium within cell cultures.HEPES is a potent inducer of lysosome biogenesis.
价 格:¥电议型 号:T8549产 地:中国大陆
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T15826Lometrexol
Lometrexol, an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and Apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.
价 格:¥电议型 号:T15826产 地:中国大陆
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T79707-Ethoxycoumarininhibit,CYPs,7 Ethoxycoumarin,Cytochrome P450,Inhibitor,7Ethoxycoumarin,7-Ethoxycoum
7-Ethoxycoumarin, a typical human P450 substrate, is catalyzed by both wild-type and mutant forms of CYP102A1.
价 格:¥电议型 号:T7970产 地:中国大陆
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TN71872,4-dibroMobenzene-1,3,5-triol
2,4-dibroMobenzene-1,3,5-triol is a marine derived natural products found in Rhabdonia verticillata.
价 格:¥电议型 号:TN7187产 地:中国大陆
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T6948Pluripotininhibit,Extracellular signal regulated kinases,Ribosomal S6 Kinase (RSK),SC-1,SC 1,Inhibit
Pluripotin (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP.
价 格:¥电议型 号:T6948产 地:中国大陆
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T7821DG172 dihydrochlorideDG-172,DG172,DG172 dihydrochloride,PPAR,inhibit,DG 172,Inhibitor,Peroxisome pro
DG172 (dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).
价 格:¥电议型 号:T7821产 地:中国大陆
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TQ0232UNC0646H3K9me2,KMT1D,chromatin,EHMT1,Histone Methyltransferase,UNC-0646,SAR,inhibit,G9a,GLP,PKMT,UNC
UNC 0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50s: 6 nM/15 nM for G9a/GLP). UNC0646 potently blocks G9a/GLP methyltransferase activity in cells (IC50: 10 nM in MCF7 cells); exhibits low cellular toxicity (EC50: 4.7 μM in MCF7 cells).
价 格:¥电议型 号:TQ0232产 地:中国大陆
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TN2011OmbuosideGynostemma pentaphyllum,antimicrobial,Parkinson?s disease,Bacterial,inhibit,Ombuoside,bacte
Ombuoside has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.
价 格:¥电议型 号:TN2011产 地:中国大陆
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TD0105Sulfobromophthalein disodium saltinhibit,Sulfobromophthalein disodium salt,MDR2,Sulfobromophthalein
Sulfobromophthalein disodium salt is an organic anion dye, it is used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites.
价 格:¥电议型 号:TD0105产 地:中国大陆
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T7804Garenoxacin mesylate hydrateGarenoxacin mesylate hydrate,DNA/RNA Synthesis,Topoisomerase,S. pneumoni
Garenoxacin mesylate hydrate with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.
价 格:¥电议型 号:T7804产 地:中国大陆
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T93234-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide4Amino6(trifluoromethyl)benzene1,3disulfonamide,
4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide is a carbonic anhydrase inhibitor, used as a potential anti-tumor and antiglaucoma drug.
价 格:¥电议型 号:T9323产 地:中国大陆
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TN4660NiranthinNiranthin,inhibit,anti-leishmanial agent,leishmaniasis,Topoisomerase,Parasite,drug-resistan
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
价 格:¥电议型 号:TN4660产 地:中国大陆
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T8005Cardiogenol C hydrochlorideInhibitor,β-catenin,plasticity,Cardiomyogenic,MHC,Wnt,inhibit,pyrimidine,
Cardiogenol C hydrochloride can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
价 格:¥电议型 号:T8005产 地:中国大陆
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TN71836-Bromo-1H-indole-3-acetic acid methyl ester
6-Bromo-1H-indole-3-acetic acid methyl ester is a marine derived natural products found in Pseudosuberites hyalinus.
价 格:¥电议型 号:TN7183产 地:中国大陆
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TN72093-bromopyrrole-2,5-dione
3-Bromo-1H-pyrrole-2,5-dione is a marine derived natural products found in marine sponge Axinella brevistyla.
价 格:¥电议型 号:TN7209产 地:中国大陆
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T8658NEO2734PER-403,SPOP,NEO-2734,CBP,NEO 2734,MYC,HAT,NEO2734,Epigenetic Reader Domain,TC-797,Histone Ac
NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).
价 格:¥电议型 号:T8658产 地:中国大陆
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T6485EmbelinEmbelin,Nuclear factor-κB,carcinoma,Nuclear factor-kappaB,NSC91874,growth,inhibit,IAP,cancer,
Embelin, isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
价 格:¥电议型 号:T6485产 地:中国大陆
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TN1068TricinTricin,CMV,Inhibitor,inhibit,Cytomegalovirus
Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells via the upregulation of focal-adhesion-finase (FAK)-targeting microRNA-7.
价 格:¥电议型 号:TN1068产 地:中国大陆
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T6786BI-9564BI-9564,Inhibitor,Epigenetic Reader Domain,inhibit
BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
价 格:¥电议型 号:T6786产 地:中国大陆