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T1158Phenoxybenzamine hydrochloride；盐酸酚苄明NCI-c01661|||NSC 37448|||Phenoxybenzamine HCl；苯氧苯札明|||NCI-c01661
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors whi
价 格：￥电议型 号：T1158产 地：中国大陆
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T11558Hexyl gallate没食子酸己酯没食子酸己酯|||Gallic acid hexyl ester|||Hexyl 3,4,5-trihydroxybenzoate
Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).
价 格：￥电议型 号：T11558产 地：中国大陆
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T11517GV-58；化合物GV-58GV-58
GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel). The inhibitory of GV-58 is 20-fold fewer for CDK kinases activity.
价 格：￥电议型 号：T11517产 地：中国大陆
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T11458GPR40/FFAR1 modulator 1；化合物GPR40/FFAR1 modulator 1GPR40/FFAR1 modulator 1
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.
价 格：￥电议型 号：T11458产 地：中国大陆
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T11438GNE-1858；化合物GNE-1858GNE-1858
GNE-1858 is an ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor (IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA).
价 格：￥电议型 号：T11438产 地：中国大陆
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T11358Lgamma-secretase modulator 1 hydrochloride；化合物 T11358Lgamma-secretase modulator 1 hydrochloride (1172
gamma-secretase inhibitior-1 is a gamma-secretase modulator that is useful to Alzheimer´s disease [1].
价 格：￥电议型 号：T11358L产 地：中国大陆
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T11358gamma-secretase modulator 1；化合物gamma-secretase modulator 1N-[3-methoxy-4-(4-methylimidazol-1-yl)phen
gamma-secretase modulator 1 is a modulator of γ secretase and can be used in studies about the treatment of Alzheimer´s disease.
价 格：￥电议型 号：T11358产 地：中国大陆
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T11338Furamidine；化合物 T11338DB75|||NSC 305831；DB75|||NSC 305831
Furamidine is also a selective and cell-permeable protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC50s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine (DB75) is abisbenzamidine derivative and an antiparasite agent. Furamidine is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine is effective both with single- and
价 格：￥电议型 号：T11338产 地：中国大陆
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T11250Ezetimibe-d4；化合物 T11250SCH 58235 D4；SCH 58235 D4
Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
价 格：￥电议型 号：T11250产 地：中国大陆
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T11229Erlotinib-d6；化合物 T11229OSI-774 D6|||NSC 718781 D6|||CP-358774 D6；OSI-774 D6|||NSC 718781 D6|||CP-358
Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
价 格：￥电议型 号：T11229产 地：中国大陆
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T11214EPI-589；化合物 T11214EPI-589
EPI-589, a quinone derivative and oxidoreductase enzyme inhibitor, is considered safe and well tolerated, showing promise for the treatment of amyotrophic lateral sclerosis (ALS).
价 格：￥电议型 号：T11214产 地：中国大陆
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T11205ent-Ezetimibe；ENT-依折麦布ent-SCH 58235；ent-SCH 58235|||ENT-依折麦布
Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?
价 格：￥电议型 号：T11205产 地：中国大陆
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T11158EGFR-IN-11；化合物EGFR-IN-11EGFR-IN-11
EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.
价 格：￥电议型 号：T11158产 地：中国大陆
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T11058DM3；化合物 T11058Maytansinoid DM3；Maytansinoid DM3
DM3 (Maytansinoid DM3) is a maytansine mimic containing disulfide or thiol groups and a tubulin inhibitor. It is the cytotoxic part of antibody-drug conjugates (ADCs) .
价 格：￥电议型 号：T11058产 地：中国大陆
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T10958Dapagliflozin-d5；化合物 T10958BMS-512148 D5；BMS-512148 D5
Dapagliflozin D5 (BMS-512148 D5) is deuterated Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.
价 格：￥电议型 号：T10958产 地：中国大陆
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T10858COH34 analog 1；COH34类似物1COH34 analog 1
COH34 analog 1 is a COH34 oxidation analogue that can be used to synthesize active compounds.
价 格：￥电议型 号：T10858产 地：中国大陆
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T10839Clozic；氯丁扎利Clobuzarit|||ICI 55897；氯丁扎利|||Clobuzarit|||ICI 55897
Clozic (ICI 55897) exhibits reversible anti-proliferative effects and can be used in studies about serving as a potential anti-arthritic agent.
价 格：￥电议型 号：T10839产 地：中国大陆
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T10759CEP-28122 mesylate salt (1022958-60-6 free base)；化合物CEP-28122 mesylate saltCEP-28122 mesylate salt；C
CEP-28122 mesylate salt (1022958-60-6 free base) is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in an enzyme-based TRF assay).
价 格：￥电议型 号：T10759产 地：中国大陆
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T10758LCentanafadine hydrochloride；化合物Centanafadine hydrochlorideEB-1020 hydrochloride；EB-1020 hydrochlorid
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
价 格：￥电议型 号：T10758L产 地：中国大陆
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T10758Centanafadine；化合物 T10758EB-1020；EB-1020
Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
价 格：￥电议型 号：T10758产 地：中国大陆
