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T1073Dronedarone hydrochloride;盐酸决奈达隆Dronedarone HCl|||SR33589;Dronedarone HCl|||SR33589|||决奈达隆盐酸盐|||盐酸决奈
Dronedarone hydrochloride (SR33589) is an amiodarone analog which has an effective and promising treatment for Atrial fibrillation.
价 格:¥电议型 号:T1073产 地:中国大陆
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T10692LNumidargistat;化合物 T10692LINCB01158|||CB-1158;INCB01158|||CB-1158
CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692L产 地:中国大陆
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T10692CB-1158 dihydrochloride (2095732-06-0 free base);化合物 T10692INCB01158 dihydrochloride|||CB-1158 dihyd
CB-1158 dihydrochloride is an effective and orally active inhibitor of arginase (IC50s: 86 nM and 296 nM for recombinant human arginase 1 and 2).
价 格:¥电议型 号:T10692产 地:中国大陆
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T10658CA inhibitor 1;化合物 T10658GS-6207 analog;GS-6207 analog
CA inhibitor 1 (GS-6207 analog) is a potent inhibitor of the HIV capsid.
价 格:¥电议型 号:T10658产 地:中国大陆
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T10589LBPN-15606;化合物 T10589LBPN-15606
BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits favorable pharmacokinetic/pharmacodynamic (PK/PD) properties, such as bioavailability, half-life, and clearance. Importantly, BPN-15606 markedly decreases Aβ42 and Aβ40 levels in the central nervous system of both rats and mice[1].
价 格:¥电议型 号:T10589L产 地:中国大陆
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T10589BPN-15606 besylate (1914989-49-3 free base);化合物 T10589BPN-15606 besylate;BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格:¥电议型 号:T10589产 地:中国大陆
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T10588BPI-9016M;化合物 T10588BPI-9016M
BPI-9016M is an effective, orally active, and selective dual inhibitor of c-Met and AXL tyrosine kinases. It suppresses tumor cell growth, invasion, and migration of lung adenocarcinoma.
价 格:¥电议型 号:T10588产 地:中国大陆
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T10587BPH-652;化合物 T10587BPH-652
BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation).
价 格:¥电议型 号:T10587产 地:中国大陆
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T10586LBPH-1358;化合物BPH-1358NSC50460;NSC50460
BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].
价 格:¥电议型 号:T10586L产 地:中国大陆
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T10586BPH-1358 free base;化合物 T10586NSC50460 free base;NSC50460 free base
BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
价 格:¥电议型 号:T10586产 地:中国大陆
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T10585Bozitinib;化合物BozitinibCBT-101|||PLB-1001;CBT-101|||PLB-1001
Bozitinib (PLB-1001) (PLB-1001) is a highly selective inhibitor of the c-MET kinase with blood-brain barrier permeability. Bozitinib binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily.
价 格:¥电议型 号:T10585产 地:中国大陆
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T10584Bovinic acid;9Z,11E十八碳二烯酸(9Z,11E)-Octadecadienoic acid|||Rumenic acid;(9Z,11E)-Octadecadienoic acid|
Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly.
价 格:¥电议型 号:T10584产 地:中国大陆
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T10582Borrelidin;化合物 T10582Treponemycin;Treponemycin
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
价 格:¥电议型 号:T10582产 地:中国大陆
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T10581Boc-MLF TFA (67247-12-5 free base);化合物 T10581Boc-Met-Leu-Phe-OH (TFA)|||Boc-MLF TFA;Boc-Met-Leu-Phe-
Boc-MLF (TFA) is a specific antagonist of formyl peptide receptor (FPR) and also inhibits signaling through FPRL1 at higher concentrations.
价 格:¥电议型 号:T10581产 地:中国大陆
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T10580BOC-D-FMK;3-[[叔丁氧羰基]氨基]-5-氟-4-氧代戊酸甲酯BOC-D-FMK
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).
价 格:¥电议型 号:T10580产 地:中国大陆
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T1058Carboplatin;卡铂NSC 241240|||CBDCA|||JM-8;NSC 241240|||卡铂|||CBDCA|||JM-8
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.
价 格:¥电议型 号:T1058产 地:中国大陆
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T10558Blonanserin D5;化合物 T10558AD-5423 D5;AD-5423 D5
Blonanserin D5 is a deuterium-labeled Blonanserin. Blonanserin (AD-5423) is a dopamine D2/5-HT2 receptor antagonist with an atypical antipsychotic effect.
价 格:¥电议型 号:T10558产 地:中国大陆
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T10501YM158 free base;化合物 T10501YM-57158;YM-57158
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).
价 格:¥电议型 号:T10501产 地:中国大陆
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T10458Banoxantrone (D12);化合物 T10458Banoxantrone (D12)|||Banoxantrone D12|||Banoxantrone (D-12)|||Banoxantr
Banoxantrone D12 (AQ4N D12) is the deuterium-labeled Banoxantrone. Banoxantrone is a bioreductive agent that can be reduced to a stable, DNA-affinity compound AQ4, which is a topoisomerase II inhibitor.
价 格:¥电议型 号:T10458产 地:中国大陆
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T10385ASP-4058;化合物ASP-4058ASP-4058
ASP-4058 is a selective, safe, and orally active second-generation agonist of sphingosine phosphate receptors 1 and 5 (S1P1 and S1P5).ASP-4058 ameliorates experimental autoimmune encephalomyelitis in mice.
价 格:¥电议型 号:T10385产 地:中国大陆