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T17733ATRA-hydroxyimino；化合物 T17733CRABP-II ligand 1；CRABP-II ligand 1
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].
价 格：￥电议型 号：T17733产 地：中国大陆
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T17732CL2A；化合物 T17732CL2A|||CL-2A|||CL2A；CL2A|||CL-2A|||CL2A
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1].
价 格：￥电议型 号：T17732产 地：中国大陆
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T17731LCL2A-SN-38 DCA 1279680-68-0(free base)；化合物CL2A-SN-38 DCACL2A-SN-38 DCA 1279680-68-0(free base)
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable t
价 格：￥电议型 号：T17731L产 地：中国大陆
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T17731CL2A-SN-38；化合物CL2A-SN-38CL2A|||CL2A SN 38|||bystander effect|||SN-38|||antitumor|||CL2A-SN-38|||Inhi
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a nonclaevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulf
价 格：￥电议型 号：T17731产 地：中国大陆
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T17730CL2 Linker；化合物 T17730CL2 Linker
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2].
价 格：￥电议型 号：T17730产 地：中国大陆
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T1773Afatinib Dimaleate；双马来酸盐阿法替尼BIBW2992|||Afatinib|||BIBW 2992MA2|||Afatinib (BIBW2992) Dimaleate；马来酸阿法
Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.
价 格：￥电议型 号：T1773产 地：中国大陆
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T17729Cl-C6-PEG4-C3-COOH；化合物 T17729Cl-C6-PEG4-C3-COOH
Cl-C6-PEG4-C3-COOH, a PROTAC linker, is a suitable component for synthesizing chloroalkane-containing PROTACs (HaloPROTACs).
价 格：￥电议型 号：T17729产 地：中国大陆
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T17728PROTAC CDK9 degrader-2；化合物 T17728PROTAC CDK9 degrader-2
PROTAC CDK9 degrader-2 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
价 格：￥电议型 号：T17728产 地：中国大陆
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T17727CCK2R Ligand-Linker Conjugates 1；化合物 T17727CCK2R Ligand-Linker Conjugates 1
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
价 格：￥电议型 号：T17727产 地：中国大陆
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T17726Cbz-Phe-(Alloc)Lys-PAB-PNP；化合物 T17726CbzPhe(Alloc)LysPABPNP|||Cbz Phe (Alloc)Lys PAB PNP|||Cbz-Phe-(
Cbz-Phe-(Alloc)Lys-PAB-PNP serves as a cleavable linker in the design of antibody-drug conjugates (ADC).
价 格：￥电议型 号：T17726产 地：中国大陆
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T17725Cbz-NH-PEG8-CH2COOH；化合物 T17725Cbz-NH-PEG8-CH2COOH
Cbz-NH-PEG8-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17725产 地：中国大陆
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T17724Cbz-NH-PEG5-CH2COOH；化合物Cbz-NH-PEG5-CH2COOHCbz-NH-PEG5-CH2COOH
Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17724产 地：中国大陆
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T17723Cbz-NH-PEG36-C2-acid；化合物 T17723Cbz-NH-PEG36-C2-acid
Cbz-NH-PEG36-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17723产 地：中国大陆
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T17722Cbz-NH-PEG3-CH2COOH；苯甲氧羰酰基二聚乙二醇羧乙基Inhibitor|||PROTAC Linkers|||inhibit|||CbzNHPEG3CH2COOH|||Cbz-NH-P
Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17722产 地：中国大陆
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T17721Cbz-NH-PEG24-C2-acid；化合物 T17721Cbz-NH-PEG24-C2-acid
Cbz-NH-PEG24-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17721产 地：中国大陆
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T17720Cbz-NH-PEG2-CH2COOH8-苄氧羰基氨基-3,6-二氧杂辛酸8-苄氧羰基氨基-3,6-二氧杂辛酸
Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17720产 地：中国大陆
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T1772MDK83190；化合物Apoptosis Activator 2Apoptosis Activator 2；Apoptosis Activator 2
MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .
价 格：￥电议型 号：T1772产 地：中国大陆
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T17719Cbz-NH-PEG12-C2-acid；化合物Cbz-NH-PEG12-C2-acidCbz-NH-PEG12-C2-acid
Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17719产 地：中国大陆
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T17718Cbz-NH-PEG10-CH2COOH；化合物 T17718Cbz-NH-PEG10-CH2COOH
Cbz-NH-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T17718产 地：中国大陆
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T17717Cbz-NH-PEG1-CH2COOH苄氧羰基聚乙二醇乙酸苄氧羰基聚乙二醇乙酸
Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格：￥电议型 号：T17717产 地：中国大陆
