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T12216NF-56-EJ40;化合物NF-56-EJ40NF-56-EJ40
NF-56-EJ40 is an effective and highly selective antagonist of human SUCNR1 with an IC50 of 25 nM and a Ki of 33 nM.
价 格:¥电议型 号:T12216产 地:中国大陆
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T1214588011-6561;化合物 8011-65618011-6561
1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-ol is an anticholinergic agent that has the potential for the research of bronchial asthma [1].
价 格:¥电议型 号:T121458产 地:中国大陆
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T12126MUT056399;化合物MUT056399Fab-001;Fab-001
MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli (IC50s of 12 nM and 58 nM, respectively).
价 格:¥电议型 号:T12126产 地:中国大陆
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T121011TLC1566-0618;化合物TLC1566-0618TLC1566-0618
TLC1566-0618 shows antitumor activity and targets stat.
价 格:¥电议型 号:T121011产 地:中国大陆
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T120656N004-0015;化合物 N004-0015N004-0015
Plasmodium falciparum, EC50: 7.21 nM
价 格:¥电议型 号:T120656产 地:中国大陆
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T12056MK-0941 free base;MK-0941 FREE BASEMK-0941 free base
MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.
价 格:¥电议型 号:T12056产 地:中国大陆
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T11979McN5691;化合物 McN5691MCN 5691|||RWJ26240;MCN 5691|||RWJ26240
McN5691 (RWJ26240) is a voltage-dependent calcium channel blocker with antihypertensive activity that can be used in the study of diseases caused by vascular smooth muscle abnormalities.
价 格:¥电议型 号:T11979产 地:中国大陆
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T11956MBC-11 triethylamine;化合物 T11956MBC-11 triethylamine
MBC-11 triethylamine has potential to treat tumor-induced bone disease (TIBD), is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC).
价 格:¥电议型 号:T11956产 地:中国大陆
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T11951Mavoglurant racemate;化合物 T11951AFQ-056 racemate;AFQ-056 racemate
Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.
价 格:¥电议型 号:T11951产 地:中国大陆
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T11856LIT-001 free base;化合物 T11856LIT-001 free base
LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM).
价 格:¥电议型 号:T11856产 地:中国大陆
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T11826LCH-7749944;化合物LCH-7749944GNF-PF-2356;GNF-PF-2356
LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.
价 格:¥电议型 号:T11826产 地:中国大陆
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T1178Temozolomide;替莫唑胺NSC 362856|||TZM|||CCRG 81045|||TMZ;NSC 362856|||替莫唑胺|||TZM|||CCRG 81045|||TMZ
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.
价 格:¥电议型 号:T1178产 地:中国大陆
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T11756Kgp-IN-1;化合物 T11756Kgp-IN-1
Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.
价 格:¥电议型 号:T11756产 地:中国大陆
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T11700J-2156;化合物 T11700J-2156
The ED50 of J-2156 in rats for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws was 3.7 and 8.0 mg/kg, respectively. J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC50s of 0.05 nM and 0.07 nM for human and rat SST4 receptors, respectively.
价 格:¥电议型 号:T11700产 地:中国大陆
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T11606ICA-105665;化合物 T11606PF-04895162;PF-04895162
ICA-105665 (PF-04895162) is a potent and orally active neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels opener. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects[1][2][3][4].
价 格:¥电议型 号:T11606产 地:中国大陆
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T11584Hydroxy desmethyl Bosentan;化合物 T11584Ro 64-1056;Ro 64-1056
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver.
价 格:¥电议型 号:T11584产 地:中国大陆
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T11569HKI-357;化合物HKI-357HKI-357
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM). HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
价 格:¥电议型 号:T11569产 地:中国大陆
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T11568HIV-1 integrase inhibitor 4;化合物 T11568HIV-1 integrase inhibitor 4
HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).
价 格:¥电议型 号:T11568产 地:中国大陆
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T11567HIV-1 integrase inhibitor 3;化合物 T11567HIV-1 integrase inhibitor 3
HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).
价 格:¥电议型 号:T11567产 地:中国大陆
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T11566HIV-1 integrase inhibitor;化合物 T11566HIV-1 integrase inhibitor
Hiv-1 integrase inhibitor is an effective anti-HIV drug.
价 格:¥电议型 号:T11566产 地:中国大陆