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T36086CAY10567CAY10567CAY-10567|||CAY10567
CAY10567 has a wide range of applications in life science related research.
价 格：￥电议型 号：T36086产 地：中国大陆
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T35989CAY10565；CAY10565CAY10565
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10565 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of 130 minutes in 0.1 M phosphate buffer, pH 5.0,
价 格：￥电议型 号：T35989产 地：中国大陆
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T35988CAY10564；CAY10564CAY10564
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10564 is a member of a new class of S-nitrosothiol species that act as NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5.0,
价 格：￥电议型 号：T35988产 地：中国大陆
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T35987CAY10563；CAY10563CAY10563；CAY10563
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO). CAY10563 is a member of a new class of S-nitrosothiol species that act as an NO donors under acidic conditions. It decomposes with a half-life of one minute in 0.1 M phosphate buffer, pH 5.
价 格：￥电议型 号：T35987产 地：中国大陆
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T35986CAY10512CAY10512CAY10512|||CAY-10512
The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activatio
价 格：￥电议型 号：T35986产 地：中国大陆
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T35813CAY10592CAY10592CAY-10592|||CAY 10592|||CAY10592
Peroxisome proliferator-activated receptors (PPARs) α, δ, γ are ligand-activated nuclear transcription factors involved in the regulation of energy homeostasis as well as insulin sensitivity and glucose metabolism. Pharmacologies of PPARδ receptor agonists, though relatively obscure, have recently been reported to elevate high-density lipoprotein (HDL) cholesterol and lower plasma triglyceride (TG) levels in obese insulin resistant rhesus monkeys. CAY10592 is a full PPARδ agonist (EC50 = 30 nM)
价 格：￥电议型 号：T35813产 地：中国大陆
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T35812CAY10591；CAY10591CAY10591；CAY10591
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1, such as resveratrol, extend lifespan in yeast and C. elegans in a manner that resembles caloric restriction. CAY10591 has been identified as an activator of the enzyme SIRT1. This com
价 格：￥电议型 号：T35812产 地：中国大陆
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T3520Setipiprant；塞替匹仑KYTH-105|||ACT-129968；KYTH-105|||塞替匹仑|||ACT-129968
Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and asthma. Binding of PGD2 to CRTH2, which are expressed on the surface of blood-borne cells, induces chemotaxis of Th2 cells, basophils, and eosinophils, and stimulates cytokine release from these cells.
价 格：￥电议型 号：T3520产 地：中国大陆
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T35105Way 100252；化合物 T35105Way-100252|||Way100252；Way-100252|||Way100252
Way 100252 inhibits evoked [3H]GABA release when tested against a number of release-inducing stimuli.
价 格：￥电议型 号：T35105产 地：中国大陆
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T3494LW6；化合物LW6HIF-1α inhibitor|||CAY10585|||LW8；HIF-1α inhibitor|||CAY10585|||LW8
LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.
价 格：￥电议型 号：T3494产 地：中国大陆
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T34378RO-61-0593；化合物 T34378RO 610593|||RO 61-0593；RO 610593|||RO 61-0593
RO-61-0593 is a bioactive chemical.
价 格：￥电议型 号：T34378产 地：中国大陆
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T34377RO-61-0591；化合物 T34377RO610591|||RO61-0591；RO610591|||RO61-0591
RO-61-0591 is a bioactive chemical.
价 格：￥电议型 号：T34377产 地：中国大陆
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T33575N-Acetylsarcolysinylleucine；化合物 T33575NSC261105|||NSC 261105|||NSC-261105；NSC261105|||NSC 261105|||N
N-Acetylsarcolysinylleucine is a bioactive chemical.
价 格：￥电议型 号：T33575产 地：中国大陆
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T33262Mdl 201053；化合物 T33262Mdl 201117；Mdl 201117
Mdl 201053 is a biochemical.
价 格：￥电议型 号：T33262产 地：中国大陆
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T32894LS 105790；化合物 T32894LS105790|||LS-105790；LS105790|||LS-105790
LS 105790 is a bioactive chemical.
价 格：￥电议型 号：T32894产 地：中国大陆
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T32105Cipepofol；化合物 T32105HSK3486|||HSK 3486|||HSK-3486；HSK3486|||HSK 3486|||HSK-3486
HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.
价 格：￥电议型 号：T32105产 地：中国大陆
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T3176APD597；化合物APD597JNJ-38431055；JNJ-38431055
APD597 (JNJ-38431055) is a GPR119 agonist, used in the treatment of type 2 diabetes.
价 格：￥电议型 号：T3176产 地：中国大陆
