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T15142Vebufloxacin;化合物 T15142OPC7241|||Flumenique|||DM8966;OPC7241|||Flumenique|||DM8966
Vebufloxacin (OPC-7251) shows potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. It has potent activity characteristically against Propionibacterium acnes.
价 格:¥电议型 号:T15142产 地:中国大陆
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T14967Cimlanod;化合物 T14967BMS-986231|||CXL-1427;BMS-986231|||CXL-1427
Cimlanod is a second-generation Nitroxyl (HNO) donor for heart failure with positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream.
价 格:¥电议型 号:T14967产 地:中国大陆
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T1462Captopril;卡托普利SQ 14225|||SQ-14534|||SA333;SQ 14225|||甲巯丙脯酸|||卡托普利|||SQ-14534|||SA333
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.
价 格:¥电议型 号:T1462产 地:中国大陆
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T14299AP20187;化合物AP20187B/B Homodimerizer;B/B Homodimerizer
AP20187 (B/B Homodimerizer) is a cell-permeable compound employed to dimerize FK506-binding protein (FKBP) fusion proteins, thereby initiating biological signaling cascades, gene expression, or disrupting protein-protein interactions.
价 格:¥电议型 号:T14299产 地:中国大陆
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T14298Rimiducid;AP1903Rimiducid
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-linking the FKBP domains. It dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis.
价 格:¥电议型 号:T14298产 地:中国大陆
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T14297AP1867;化合物 T14297AP1867
AP1867 is a synthetic FKBP12F36V-directed ligand.
价 格:¥电议型 号:T14297产 地:中国大陆
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T14296Antitumor agent-3;化合物 T14296Antitumor agent-3
Antitumor agent-3 is a potent compound. It comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
价 格:¥电议型 号:T14296产 地:中国大陆
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T14295Antipain;化合物 T14295Antipain
Antipain is a protease inhibitor isolated from Actinomycetes. Antipain inhibits N-methyl-N´-nitro-N-nitrosoguanidine (MNNG)-induced transformation and increases chromosomal aberrations[1][2].
价 格:¥电议型 号:T14295产 地:中国大陆
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T14293Annonacin;化合物 T14293Annonacin
Annonacin is an Acetogenin and promotes cytotoxicity via a pathway inhibiting the mitochondrial complex and it is the active agent found in Graviola leaf extract to act as an inhibitor of sodium/potassium (NKA) and sarcoplasmic reticulum (SERCA) ATPase pumps[1].
价 格:¥电议型 号:T14293产 地:中国大陆
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T14292Anitrazafen;阿尼扎芬LY 122512;阿尼扎芬|||LY 122512
Anitrazafen is a locally effective anti-inflammatory agent that has been shown to have COX-2 inhibitor activity.
价 格:¥电议型 号:T14292产 地:中国大陆
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T14291Anisindione;茴茚二酮Anisindione
Anisindione is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins.
价 格:¥电议型 号:T14291产 地:中国大陆
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T14290Anipamil;阿尼帕米Anipamil
Anipamil is a long-acting blocker of calcium channel,and for the treatment of cardiovascular disease.
价 格:¥电议型 号:T14290产 地:中国大陆
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T142917α-Hydroxyprogesterone;17α-羟孕酮Hydroxyprogesterone|||17-OHP|||17-Hydroxyprogesterone;Hydroxyprogeste
17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression.
价 格:¥电议型 号:T1429产 地:中国大陆
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T14289Anguizole;化合物 T14289Anguizole
Anguizole, a small molecule, effectively inhibits Hepatitis C Virus (HCV) replication by modifying the subcellular distribution of NS4B. It demonstrates its potency with an IC50 value, highlighting its specific target action against HCV.
价 格:¥电议型 号:T14289产 地:中国大陆
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T14287Ancarolol;化合物 T14287Ancarolol
Ancarolol is a blocking agent of beta-adrenergic.
价 格:¥电议型 号:T14287产 地:中国大陆
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T14286ANB-NOS;化合物 T14286ANB-NOS
ANB-NOS is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T14286产 地:中国大陆
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T14285AN11251;化合物 T14285AN11251
AN11251, a potent oral-active anti-Wolbachia agent, shows promise for treating onchocerciasis and lymphatic filariasis. Demonstrating EC50 values of 1.5 nM in LDW1 cell lines and 15 nM in C6/36 cell lines, it exhibits significant efficacy across different laboratory settings.
价 格:¥电议型 号:T14285产 地:中国大陆
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T14284β-Amyloid (25-35);BETA-淀粉样蛋白片断25-35β-Amyloid peptide(25-35)|||Aβ25-35|||Amyloid beta-peptide(25-35);
β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer´s amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.
价 格:¥电议型 号:T14284产 地:中国大陆
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T14283amyloid P-IN-1;化合物amyloid P-IN-1amyloid P IN 1|||amyloid P-IN-1|||amyloid PIN1;amyloid P IN 1|||amyl
amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer´s disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.
价 格:¥电议型 号:T14283产 地:中国大陆
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T14282Amuvatinib hydrochloride;化合物 T14282HPK 56 hydrochloride|||MP470 hydrochloride;HPK 56 hydrochloride||
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally administred multi-targeted tyrosine kinase inhibitor that exhibits strong efficacy against mutant forms of c-Kit, PDGFRα, Flt3, c-Met, and c-Ret, while also acting as a suppressor of DNA repair by inhibiting the RAD51 protein, which is crucial for repairing DNA damage[1][2][3]. This dual mechanism contributes to its antineoplastic activity[4].
价 格:¥电议型 号:T14282产 地:中国大陆