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已选条件
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T17663Boc-NH-PEG10-NHS ester;化合物 T17663Boc-NH-PEG10-NHS ester
Boc-NH-PEG10-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17663产 地:中国大陆
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T17662Boc-NH-PEG10-CH2CH2NH2;化合物 T17662Boc-NH-PEG10-CH2CH2NH2
Boc-NH-PEG10-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17662产 地:中国大陆
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T17661Boc-NH-PEG10-CH2CH2COOH;化合物 T17661Boc-NH-PEG10-CH2CH2COOH
Boc-NH-PEG10-CH2CH2COOH is a polyethylene glycol (PEG)-based PROTAC linker utilized for PROTAC synthesis[1].
价 格:¥电议型 号:T17661产 地:中国大陆
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T17660Boc-NH-PEG1-Ph-O-CH2COOH;化合物 T17660Boc-NH-PEG1-Ph-O-CH2COOH
Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC Linker which is used for the EED-targeted PROTAC[1].
价 格:¥电议型 号:T17660产 地:中国大陆
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T1766Empagliflozin恩格列净BI 10773|||恩格列净
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes.
价 格:¥电议型 号:T1766产 地:中国大陆
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T17659Boc-NH-PEG1-OHN-(叔丁氧羰基)乙醇胺N-(叔丁氧羰基)乙醇胺
Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17659产 地:中国大陆
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T17658Boc-NH-PEG-amine (MW 5000);化合物 T17658Boc-NH-PEG-amine (MW 5000)
Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker enabling the synthesis of PROTACs [1].
价 格:¥电议型 号:T17658产 地:中国大陆
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T17657Boc-NH-PEG-amine (MW 3400);化合物 T17657Boc-NH-PEG-amine (MW 3400)
Boc-NH-PEG-amine (MW 3400) serves as a PEG-based PROTAC linker and finds application in PROTAC synthesis[1].
价 格:¥电议型 号:T17657产 地:中国大陆
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T17656Boc-NH-PEG-amine (MW 2000);化合物 T17656Boc-NH-PEG-amine (MW 2000)
Boc-NH-PEG-amine (MW 2000) is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1].
价 格:¥电议型 号:T17656产 地:中国大陆
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T17655Boc-NH-O-C1-NHS ester[(叔丁氧羰基氨基氧]乙酸N-琥珀酰亚胺酯[(叔丁氧羰基氨基氧]乙酸N-琥珀酰亚胺酯
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17655产 地:中国大陆
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T17654Boc-NH-C6-BrN-BOC-6-溴代己胺N-BOC-6-溴代己胺
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC).
价 格:¥电议型 号:T17654产 地:中国大陆
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T17653Boc-NH-C4-acidBoc-5-氨基戊酸Boc-5-氨基戊酸
Boc-NH-C4-acid is a PROTAC linker belonging to the Alkyl/ether class, which can be used for the synthesis of PROTAC1 and can degrade EED, EZH2, and SUZ12 in PRC2.
价 格:¥电议型 号:T17653产 地:中国大陆
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T17652Boc-NH-C12-NH2(12-氨基十二烷基)氨基甲酸叔丁酯(12-氨基十二烷基)氨基甲酸叔丁酯
Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.
价 格:¥电议型 号:T17652产 地:中国大陆
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T17651Boc-N-PEG2-Ms;化合物 T17651Boc-N-PEG2-Ms
Boc-N-PEG2-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17651产 地:中国大陆
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T17650Boc-N-Amido-PEG5-Ms;化合物 T17650Boc-N-Amido-PEG5-Ms
Boc-N-Amido-PEG5-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T17650产 地:中国大陆
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T1765Erastin;化合物ErastinErastin
Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations. The product is unstable in solution and is recommended to be dispensed now.
价 格:¥电议型 号:T1765产 地:中国大陆
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T17649Boc-GABA-OH;N-BOC-GAMMA-氨基丁酸Boc-GABA-OH
Boc-GABA-OH serves as a PROTAC linker essential for synthesizing UNC6852, an EED-targeted PROTAC[1].
价 格:¥电议型 号:T17649产 地:中国大陆
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T17648Boc-C16-NHS ester;化合物 T17648Boc-C16-NHS ester
Boc-C16-NHS ester, an alkyl/ether-based PROTAC linker, enables the synthesis of PROTACs[1].
价 格:¥电议型 号:T17648产 地:中国大陆
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T17647Boc-C1-PEG3-C4-OH;化合物 T17647Boc-C1-PEG3-C4-OH
Boc-C1-PEG3-C4-OH is an Alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs, which are characterized by their structure comprising two distinct ligands tethered by a linker. One ligand of PROTACs binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs facilitate the targeted degradation of specific proteins[1].
价 格:¥电议型 号:T17647产 地:中国大陆
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T17646Boc-C1-PEG3-C4-OBn;化合物 T17646Boc-C1-PEG3-C4-OBn
Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PEG-based PROTAC linker employed in the synthesis of various PROTACs, including PROTAC SGK3 degrader-1. PROTACs are composed of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, while the other specifically interacts with the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs can selectively degrade target proteins[1].
价 格:¥电议型 号:T17646产 地:中国大陆