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T18550(+)-Biotin-PEG6-hydrazide；化合物 T18550(+)-Biotin-PEG6-hydrazide
(+)-Biotin-PEG6-hydrazide is a polyethylene glycol (PEG) derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
价 格：￥电议型 号：T18550产 地：中国大陆
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T1855ZCL278；化合物ZCL 278ZCL 278；ZCL 278
ZCL278 is a selective Cdc42 GTPase inhibitor.
价 格：￥电议型 号：T1855产 地：中国大陆
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T18549(+)-Biotin-PEG2-hydrazide；化合物 T18549(+)-Biotin-PEG2-hydrazide
(+)-Biotin-PEG2-hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18549产 地：中国大陆
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T18548(+)-Biotin-PEG12-OH；化合物 T18548(+)-Biotin-PEG12-OH
(+)-Biotin-PEG12-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18548产 地：中国大陆
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T18547(+)-Biotin-PEG10-OH；化合物 T18547(+)-Biotin-PEG10-alcohol；(+)-Biotin-PEG10-alcohol
(+)-Biotin-PEG10-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18547产 地：中国大陆
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T18546(+)-Biotin-ONP(+)-生物素对硝基苯酯(+)-生物素对硝基苯酯|||(+)-Biotin 4-nitrophenyl ester
(+)-Biotin-ONP ((+)-Biotin 4-nitrophenyl ester) is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T18546产 地：中国大陆
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T18545Pip-alkyne-Ph-COOCH3；化合物 T18545Pip-alkyne-Ph-COOCH3
Pip-alkyne-Ph-COOCH3 is an alkyl-chain based PROTAC linker utilized for the synthesis of PROTAC ARD-266[1].
价 格：￥电议型 号：T18545产 地：中国大陆
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T18544Phthalimide-PEG4-PDM-OTBS；化合物 T18544Phthalimide-PEG4-PDM-OTBS
Phthalimide-PEG4-PDM-OTBS is a PROTAC linker comprised of polyethylene glycols (PEGs). This compound is utilized in the synthesis of a range of PROTACs, which consists of two distinct ligands connected by a linker. One ligand binds to an E3 ubiquitin ligase, while the other ligand binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1].
价 格：￥电议型 号：T18544产 地：中国大陆
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T18543Phthalimide-PEG4-MPDM-OH；化合物 T18543Phthalimide-PEG4-MPDM-OH
Phthalimide-PEG4-MPDM-OH, a PROTAC linker with a PEGs composition, has applications in the synthesis of various PROTACs. These PROTACs consist of a linker connecting two distinct ligands: one binds to an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively induce the degradation of target proteins [1].
价 格：￥电议型 号：T18543产 地：中国大陆
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T18542Phthalimide-PEG3-C2-OTs；化合物 T18542Phthalimide-PEG3-C2-OTs
Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker composed of PEGs. It is utilized in the synthesis of various PROTACs, which involve the connection of two distinct ligands through a linker. One ligand is specific for an E3 ubiquitin ligase, while the other ligand is designed for targeting the specific protein of interest. Through leveraging the intracellular ubiquitin-proteasome system, PROTACs are capable of selectively degrading target proteins [1].
价 格：￥电议型 号：T18542产 地：中国大陆
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T18541Phthalamide-PEG3-azide；化合物 T18541Phthalamide-PEG3-azide
Phthalamide-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18541产 地：中国大陆
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T18540Phe-Lys(Trt)-PAB；化合物Phe-Lys(Trt)-PABPhe-Lys(Trt)-PAB
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells.
价 格：￥电议型 号：T18540产 地：中国大陆
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T1854MS436；化合物MS436MS436
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
价 格：￥电议型 号：T1854产 地：中国大陆
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T18539Phe-Lys(Fmoc)-PAB；化合物 T18539Phe-Lys(Fmoc)-PAB
Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker employed in the conjugation of antibody-drug conjugates (ADCs)[1].
价 格：￥电议型 号：T18539产 地：中国大陆
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T18538MAC glucuronide phenol-linked SN-38；化合物 T18538MAC glucuronide phenol-linked SN-38
MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].
价 格：￥电议型 号：T18538产 地：中国大陆
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T18537Pentaethylene glycol di(p-toluenesulfonate)二对甲苯磺酸戊乙二醇Penta(ethylene glycol) bis(p-toluenesulfonate)|
Pentaethylene glycol di(p-toluenesulfonate) (Penta(ethylene glycol) bis(p-toluenesulfonate)) is a PEG-based PROTAC linker. Pentaethylene glycol di(p-toluenesulfonate) can be used in the synthesis of PROTACs.
价 格：￥电议型 号：T18537产 地：中国大陆
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T18536PEG7-O-Ms；化合物 T18536PEG7-O-Ms
PEG7-O-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格：￥电议型 号：T18536产 地：中国大陆
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T18535PEG4-SPDP；化合物 T18535PEG4-SPDP
PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
价 格：￥电议型 号：T18535产 地：中国大陆
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T18534PEG4-aminooxy-MMAF；化合物 T18534PEG4-aminooxy-MMAF
PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG4 linker[1].
价 格：￥电议型 号：T18534产 地：中国大陆
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T18533PEG3-C4-OBn；化合物 T18533PEG3-C4-OBn
PEG3-C4-OBn, a polyethylene glycol (PEG)-based PROTAC linker, is utilized in crafting the PROTAC SGK3 degrader-1, a potent SKG3 degrader leveraging PROTAC technology [1][2].
价 格：￥电议型 号：T18533产 地：中国大陆
