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T18514PAC;化合物 T18514PAC
PAC is a chemical conjugate consisting of an ADCs linker and PROTACs linked to an antibody. When PAC is conjugated to an antibody, it exhibits enhanced degradation of estrogen receptor-alpha (ERα) in comparison to PROTAC alone.
价 格:¥电议型 号:T18514产 地:中国大陆
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T18513OTs-C6-OBn;化合物OTs-C6-OBnOTs-C6-OBn
OTs-C6-OBn, an alkyl chain-based PROTAC linker, is utilized in the synthesis of PROTAC SGK3 degrader-1[1].
价 格:¥电议型 号:T18513产 地:中国大陆
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T18512OPSS-Val-Cit-PAB-PNP;化合物 T18512OPSS Val Cit PAB PNP|||OPSS-Val-Cit-PAB-PNP|||OPSSValCitPABPNP;OPSS V
OPSS-Val-Cit-PAB-PNP is a cleavable linker employed in ADC (antibody-drug conjugates) synthesis [1].
价 格:¥电议型 号:T18512产 地:中国大陆
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T18511OPSS-Val-Cit-PAB-OH;化合物 T18511OPSS-Val-Cit-PAB-OH
OPSS-Val-Cit-PAB-OH is an ADC linker utilized for the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T18511产 地:中国大陆
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T18510OPSS-PEG36-acid;化合物 T18510OPSS-PEG36-acid
OPSS-PEG36-acid is a 36-unit PEG linker amenable to cleavage, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18510产 地:中国大陆
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T1851ZM 336372;化合物ZM 336372Zinc00581684;Zinc00581684
ZM 336372 is a potent and selective c-Raf inhibitor.
价 格:¥电议型 号:T1851产 地:中国大陆
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T18509Oleoyl-Gly-Lys-N-(m-PEG11);化合物 T18509Oleoyl-Gly-Lys-N-(m-PEG11)
Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11 unit PEG linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
价 格:¥电议型 号:T18509产 地:中国大陆
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T18508Oleic-DBCO;化合物 T18508Oleic-DBCO
Oleic-DBCO is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
价 格:¥电议型 号:T18508产 地:中国大陆
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T18507NO2-SPP;化合物 T18507NO2-SPP
NO2-SPP is a cleavable linker that is used for making antibody-drug conjugate (ADC).
价 格:¥电议型 号:T18507产 地:中国大陆
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T18506NO2-SPP-sulfo-Me;化合物 T18506NO2-SPP-sulfo-Me
NO2-SPP-sulfo-Me is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADC)[1].
价 格:¥电议型 号:T18506产 地:中国大陆
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T18505NO2-SPDMV;化合物 T18505NO2-SPDMV
NO2-SPDMV is a cleavable linker vital in ADC synthesis. NO2-SPDMV joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T18505产 地:中国大陆
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T18504Nitro-PDS-Tubulysin M;化合物 T18504Nitro-PDS-Tubulysin M
Nitro-PDS-Tubulysin M, an ADC (Antibody-Drug Conjugate) drug-linker conjugate, exhibits potent antitumor activity. It employs Tubulysin M, a tubulin polymerization inhibitor, connected through the Nitro-PDS ADC linker.
价 格:¥电议型 号:T18504产 地:中国大陆
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T18503NHS-SS-biotin;化合物 T18503NHS-SS-biotin
NHS-SS-biotin is a cleavable linker vital in ADC synthesis. NHS-SS-biotin joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
价 格:¥电议型 号:T18503产 地:中国大陆
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T18502NHS-PEG4-(m-PEG12)3-ester;化合物 T18502NHS-PEG4-(m-PEG12)3-ester
NHS-PEG4-(m-PEG12)3-ester is a polyethylene glycol (PEG) based linker for PROTAC synthesis [1].
价 格:¥电议型 号:T18502产 地:中国大陆
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T18501NHPI-PEG4-C2-Pfp ester;化合物 T18501NHPI-PEG4-C2-Pfp ester
NHPI-PEG4-C2-Pfp ester is used as a linker for antibody-drug conjugates (ADC).
价 格:¥电议型 号:T18501产 地:中国大陆
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T18500NHPI-PEG4-C2-NHS ester;化合物 T18500NHPI-PEG4-C2-NHS ester
NHPI-PEG4-C2-NHS ester (WO2014185985A1) is a chemical compound employed as a linker in the formation of antibody-drug conjugates (ADC)[1].
价 格:¥电议型 号:T18500产 地:中国大陆
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T1850Balicatib;巴利卡替AAE581;AAE581|||巴利卡替
Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.
价 格:¥电议型 号:T1850产 地:中国大陆
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T18185m-PEG3-Sulfone-PEG3-acid;化合物 T18185m-PEG3-Sulfone-PEG3-acid
m-PEG3-Sulfone-PEG3-acid is a polyethylene glycol (PEG)-based protein degradation utilizing targeted chimera (PROTAC) linker [1].
价 格:¥电议型 号:T18185产 地:中国大陆
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T17249VZ185;化合物 T17249VZ185
VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).
价 格:¥电议型 号:T17249产 地:中国大陆
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T17185Tyrothricin;酪丝菌素Tyrothricin
Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin displays activity against bacteria, fungi, and some viruses.
价 格:¥电议型 号:T17185产 地:中国大陆